Improving patient outcomes in leukaemia by targeting cancer stem cells
Improving patient outcomes in leukaemia by targeting cancer stem cells
批准号:
nhmrc : 1064569
负责人:
A/Pr Steven Lane
金额:
$19.65万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2018-12-31
中文摘要
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英文摘要
Blood cancers such as acute myeloid leukaemia (AML) are among the most deadly types of cancer and new treatments are desperately needed to improve patient’s survival in these diseases. AML cancer-causing stem cells survive by turning on immortalization programs and we hope to specifically kill these AML stem cells by blocking these crucial pathways. This includes things that control the way the cells divide and the way they respond to genetic damage as well as other novel pathways.
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会议论文
The evolution of acute myeloid leukaemia by in situ transformation of haematopoietic stem cells
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批准号:nhmrc : GNT1098470
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项目类别:Project Grants
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资助金额:$64.7万
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财政年份:2016
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负责人:A/Pr Steven Lane
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依托单位:
The evolution of acute myeloid leukaemia by in situ transformation of haematopoietic stem cells
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批准号:nhmrc : 1098470
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项目类别:Project Grants
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资助金额:$44.35万
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财政年份:2016
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负责人:A/Pr Steven Lane
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依托单位:
Targeting leukaemia stem cells through inhibition of telomerase
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批准号:nhmrc : 1098516
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项目类别:Project Grants
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资助金额:$44.68万
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财政年份:2016
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负责人:A/Pr Steven Lane
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依托单位:
Targeting leukaemia stem cells through inhibition of telomerase
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批准号:nhmrc : GNT1098516
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项目类别:Project Grants
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资助金额:$65.2万
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财政年份:2016
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负责人:A/Pr Steven Lane
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依托单位:
Deciphering the overlapping roles of SSB1 and SSB2 in the regulation of haematopoiesis and intestinal homeostasis
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批准号:nhmrc : GNT1085367
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项目类别:Project Grants
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资助金额:$95.87万
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财政年份:2015
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负责人:A/Pr Steven Lane
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依托单位:
Deciphering the overlapping roles of SSB1 and SSB2 in the regulation of haematopoiesis and intestinal homeostasis
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批准号:nhmrc : 1085367
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项目类别:Project Grants
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资助金额:$66.46万
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财政年份:2015
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负责人:A/Pr Steven Lane
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依托单位:
Targeting disease-initiating cells in myeloproliferative neoplasms
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批准号:nhmrc : 1026594
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项目类别:Project Grants
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资助金额:$31.82万
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财政年份:2012
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负责人:A/Pr Steven Lane
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依托单位:
Molecular pathways mediating quiescence and resistance in leukaemia stem cells in acute myeloid leukaemia.
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批准号:nhmrc : 511275
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项目类别:NHMRC Postgraduate Scholarships
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资助金额:$6.69万
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财政年份:2008
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负责人:A/Pr Steven Lane
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依托单位:
海外基金