The Ohio State University Neurological Emergencies Treatment Trials (OSU NETT) N*

俄亥俄州立大学神经紧急情况治疗试验 (OSU NTT) N*

• 批准号: 8527866
• 负责人: Michel T Torbey
• 金额: $ 29.57万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8527866
• 关键词: Academic Medical Centers; Accident and Emergency department; Acute; Adult; Brain; Catchment Area; Childhood; Clinical; Clinical Research; Clinical Trials; Clinical Trials Network; Collaborations; Commit; Communities; Community Healthcare; Community Hospitals; Consent; Contracts; County; Data; Early Intervention; Emergency Medicine; Emergency Situation; Emergency treatment; Enrollment; Ensure; Faculty; Foundations; Future; Goals; Health Personnel; Healthcare; Hospitals; Hour; Informed Consent; Institution; Institutional Review Boards; Leadership; Morbidity - disease rate; National Institute of Neurological Disorders and Stroke; Neurologic; Neurological emergencies; Neurologist; Neurosciences; Neurosurgeon; Ohio; Outcome; Participant; Patients; Pediatric Hospitals; Physicians; Principal Investigator; Process; Protocols documentation; Recruitment Activity; Request for Applications; Research; Research Infrastructure; Research Personnel; Research Support; Rights; Safety; Site; Solid; Stroke; Structure; Surgeon; Telemedicine; Testing; Therapeutic; Time; Training; Training Activity; Trauma; Universities; Visit; abstracting; clinical practice; clinical research site; cost effective; design; dissemination research; experience; follow-up; human subject protection; improved; innovation; interest; member; mortality; multidisciplinary; pediatrician; programs; public health relevance; relating to nervous system; response; trauma centers; treatment trial

DESCRIPTION (provided by applicant): This proposal is in response to Request for Applications PAR-11-342 Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs for year 2011. This abstract summarizes the capability of the Ohio State University NETT network (OSUNETT) to: 1) develop a solid, cost-effective infrastructure that can quickly and efficiently implements both pediatric and adult acute neurological clinical trials; 2) To identify quickly, recruit aggressively, enroll efficiently and maintain and retain effectively the necessary study participants for each clinical study; 3) To coordinate the participation of multipl spokes in the network and ensure the safety and rights of all participants in the trials; 4) To collaborate with network members in developing and testing innovative telemedicine approaches to enhance informed trial consent process and patients follow-up; 5) To use the NETT initiatives and programs as a major component in training junior faculty, and research coordinators in the appropriate design and conduct of acute neurological clinical trials; and 5) To cooperate with other NETT Hubs in facilitating the transfer of research results to clinical practic in community hospital settings and among emergency medicine physicians. OSUNETT represents a multidisciplinary group of emergency physicians, neurointensivisits, pediatricians, neurologists, neurosurgeons, and trauma surgeons. This proposal builds on an existing research infrastructure that has supported acute neurological clinical trials both in the Emergency Department and in out-of-hospital setting using exemption from informed consent. OSUNETT has a well-established strong Hub-Spoke telestroke infrastructure with 14 spokes collaborating towards OSUNETT goals. The catchment area of OSUNETT extends over several counties with access to more than 3 million Ohio residents and more than 900,000 annual ED visits. OSUNETT is supported by 5 Level I Trauma Centers and 6 Primary Stroke Centers. OSUNETT has the experience, track record, and the support of a solid infrastructure to serve as strong participant in this important network.

描述（由申请人提供）：本提案是对2011年PAR-11-342神经急救治疗试验（NETT）网络临床站点中心申请的回应。本摘要总结了俄亥俄州立大学神经网络（OSUNETT）的能力：1)开发一个坚实的，具有成本效益的基础设施，可以快速有效地实施儿科和成人急性神经学临床试验；2)快速识别，积极招聘，高效注册，有效维护和留住员工