The Ohio State University Regional Coordinating Stroke Center

描述(申请人提供)：进行中风临床试验的传统模式的特点是基础设施和工作的冗余和重复，效率低和 招募往往不完整，很难综合各试验的数据。俄亥俄州立大学(OSU)的综合中风和神经血管中心(OSU)和全国儿童医院(NCH)正在提交此申请，以考虑作为区域协调中风中心(RCC)参与，以实现以下具体目标：1.开发可靠、具有成本效益的基础设施，可以快速有效地实施儿科和成人 涵盖脑血管疾病全范围的中风临床试验；2.快速识别、积极招募、有效招募并有效维护和保留必要的 这些研究包括：3.协调TE网络中多个发言人的参与，确保试验中所有参与者的安全和权利；通过高效地安排和完成所有研究程序以及临床中心的访问，将参与者的负担降至最低；4.与网络成员合作开发引人注目的临床研究应用程序，并测试创新的远程医疗方法，以增强试验的知情同意过程和患者随访；5.将NINDS卒中网络的倡议和计划作为培训初级教职员工的重要组成部分，以及参与适当设计和进行卒中临床试验的研究协调员。6.与网络中的其他RCC中心协调，以整合数据，并使用Stroke Common Data Element(CDE)，以促进跨研究结果的比较，并促进荟萃分析研究。

DESCRIPTION (provided by applicant): The traditional model of conducting stroke clinical trials is characterized by redundancy and duplication of infrastructure and effort, inefficient and often incomplete recruitment, and difficulty in combining data across trials. The Comprehensive Stroke and Neurovascular Center at the Ohio State University (OSU) and Nationwide Children Hospital (NCH) are submitting this application for consideration to participate as a Regional Coordinating Stroke Center (RCC) to achieve the following specific aims; 1. Develop a solid, cost-effective infrastructure that can quickly and efficiently implements both pediatric and adult stroke clinical trials encompassing the full breadth of cerebrovascular disease; 2. Identify quickly, recruit aggressively, enroll efficiently and maintain and retain effectively the necessary study participants for each clinical study; 3. Coordinate the participation of multiple spokes in te network and ensure the safety and rights of all participants in the trials; and minimize participant burden through efficient scheduling and completion of all study procedures and clinical center visits; 4. Collaborate with network members in developing compelling clinical research applications and testing innovative telemedicine approaches to enhance informed trial consent process and patients follow-up; 5. Use the NINDS stroke network initiatives and programs as a major component in training junior faculty, and research coordinators in the appropriate design and conduct of stroke clinical trials. 6. Coordinate with other RCC hubs in the network to integrate data and use Stroke Common Data Element (CDE) to facilitate comparison of results across studies and facilitate meta-analysis research.