PHILA-NETT: Neurological Emergencies Treatment Trials (NETT) Network Clinical Hub

PHILA-NETT：神经急症治疗试验 (NETT) 网络临床中心

• 批准号: 8536960
• 负责人: NINA T GENTILE
• 金额: $ 29.41万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-03 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8536960
• 关键词: Academic Medical Centers; Accident and Emergency department; Acute; Address; Adherence; Adult; African American; Agreement; Ancillary Study; Anoxic Encephalopathy; Area; Blood Glucose; Brain Injuries; Caring; Childhood; Clinical; Clinical Research; Clinical Trials; Communication; Communities; Community Health Education; Community Hospitals; Controlled Study; Critical Care; Data; Development; Discipline; Drops; Emergency Medicine; Emergency treatment; Enrollment; Ensure; Feedback; Funding; Funding Opportunities; Grant; Health system; Hospitals; Human Resources; Incidence; Informatics; Injury; Insulin; Latino; Lead; Leadership; Low income; Mission; Monitor; Morbidity - disease rate; National Institute of Neurological Disorders and Stroke; Neurologic; Neurological emergencies; Neurology; Nurses; Online Systems; Outcome; Participant; Patient Care; Patient Recruitments; Patients; Pennsylvania; Philadelphia; Physicians; Process; Protocols documentation; Provider; Public Health; Radiology Specialty; Records; Rehabilitation therapy; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Rural Community; Scientist; Seizures; Services; Site; Stroke; Structure; Survivors; System; Testing; Therapeutic; Trauma; Traumatic Brain Injury; Treatment Effectiveness; United States National Institutes of Health; Universities; Work; acute stroke; base; blood glucose regulation; career; community setting; data management; disability; disorder prevention; flexibility; fundamental research; improved; insight; meetings; mortality; natural hypothermia; neurosurgery; research study; response; standard of care; statistical center; suburb; symposium; treatment trial; trend

DESCRIPTION (provided by applicant): Temple University (TU) serves as the Clinical Hub for the Philadelphia-area Neurological Emergency Treatment Trials (PHILA-NETT) network, a consortium of community and academic medical centers formed to effectively conduct clinical studies related to neurological emergencies. Over the past four years, the primary sites have included TU Health System hospitals and Hahnemann Hospital located in low- income areas of North Philadelphia with high proportions of African American and Latino patients. Temple Clinical Hub created a highly successful organization wherein staff works closely with site investigators and coordinators from multiple disciplines to efficiently execute NETT studies across all sites. Mechanisms that have enhanced the efficiency and quality of research across sites include, for example, the use of a common web-based informatics system developed to safely and quickly identify potential study patients; frequent and regular communication among investigators and coordinators; and diligent site management focused on good clinical research practices and compliance. Over the next five years, the consortium will expand within Philadelphia and across Pennsylvania to improve our reach and to meet the needs of the NETT as a whole. The PHILA-NETT structure is strong and sustainable and yet flexible enough to allow for expansion as needed to carry out the current and anticipated NETT studies. PHILA-NETT investigators have had career-long commitment to research in acute stroke, traumatic brain injury, therapeutic hypothermia and anoxic encephalopathy, all potential areas for NETT studies. These clinician-scientists in adult and pediatric Emergency Medicine, Neurology, Neurosurgery, Trauma, and Neuro-critical care are leaders in their communities and set the standards of care for patients with acute neurological illness and injury. Working with the NETT, the group will execute and design studies to address fundamental research questions. And most important to the mission of Temple University and to the communities in the Commonwealth, we will disseminate information and study results that will serve to guide and advance the treatment of patients with neurological emergencies.

描述（由申请人提供）：坦普尔大学（TU）是费城地区神经系统紧急治疗试验（PHILA-NETT）网络的临床中心，该网络是一个由社区和学术医疗中心组成的联盟，旨在有效地进行与神经系统紧急情况相关的临床研究。在过去的四年里，主要地点包括位于费城北部低收入地区的恩卫生系统医院和哈内曼医院，非洲裔和拉丁裔患者比例很高。 Temple Clinical Hub创建了一个非常成功的组织，其中工作人员与来自多个学科的研究中心研究员和协调员密切合作，以有效地在所有研究中心执行NETT研究。提高各研究中心研究效率和质量的机制包括，例如，使用为安全和快速识别潜在研究患者而开发的通用网络信息系统;研究者和协调员之间频繁和定期的沟通;以及专注于良好临床研究实践和合规性的勤奋研究中心管理。在接下来的五年里，该联盟将在费城和整个宾夕法尼亚州扩展，以提高我们的覆盖范围，并满足整个NETT的需求。PHILA-NETT结构强大且可持续，但足够灵活，可以根据需要进行扩展，以进行当前和预期的NETT研究。 PHILA-NETT的研究人员在职业生涯中一直致力于急性中风、创伤性脑损伤、治疗性低温和缺氧性脑病的研究，这些都是NETT研究的潜在领域。这些成人和儿科急诊医学，神经病学，神经外科，创伤和神经重症监护的临床科学家是他们社区的领导者，并为急性神经系统疾病和损伤患者制定护理标准。与NETT合作，该小组将执行和设计研究，以解决基础研究问题。对坦普尔大学和英联邦社区的使命来说，最重要的是，我们将传播信息和研究结果，这些信息和研究结果将有助于指导和促进对神经系统急症患者的治疗。