PHILA-NETT: Neurological Emergencies Treatment Trials (NETT) Network Clinical Hub

PHILA-NETT：神经急症治疗试验 (NETT) 网络临床中心

• 批准号: 8701419
• 负责人: NINA T GENTILE
• 金额: $ 26.91万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-03 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8701419
• 关键词: Academic Medical Centers; Accident and Emergency department; Acute; Address; Adherence; Adult; African American; Agreement; Ancillary Study; Anoxic Encephalopathy; Area; Blood Glucose; Brain Injuries; Caring; Childhood; Clinical; Clinical Research; Clinical Trials; Communication; Communities; Community Health Education; Community Hospitals; Controlled Study; Critical Care; Data; Development; Discipline; Drops; Emergency Medicine; Emergency treatment; Enrollment; Ensure; Feedback; Funding; Funding Opportunities; Grant; Health system; Hospitals; Human Resources; Incidence; Informatics; Injury; Insulin; Latino; Lead; Leadership; Low income; Mission; Monitor; Morbidity - disease rate; National Institute of Neurological Disorders and Stroke; Neurologic; Neurological emergencies; Neurology; Nurses; Online Systems; Outcome; Participant; Patient Care; Patient Recruitments; Patients; Pennsylvania; Philadelphia; Physicians; Process; Protocols documentation; Provider; Public Health; Radiology Specialty; Records; Rehabilitation therapy; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Rural Community; Scientist; Seizures; Services; Site; Stroke; Structure; Survivors; System; Testing; Therapeutic; Trauma; Traumatic Brain Injury; Treatment Effectiveness; United States National Institutes of Health; Universities; Work; acute stroke; base; blood glucose regulation; career; community setting; data management; disability; disorder prevention; flexibility; fundamental research; improved; insight; meetings; mortality; natural hypothermia; neurosurgery; research study; response; standard of care; statistical center; suburb; symposium; treatment trial; trend

DESCRIPTION (provided by applicant): Temple University (TU) serves as the Clinical Hub for the Philadelphia-area Neurological Emergency Treatment Trials (PHILA-NETT) network, a consortium of community and academic medical centers formed to effectively conduct clinical studies related to neurological emergencies. Over the past four years, the primary sites have included TU Health System hospitals and Hahnemann Hospital located in low- income areas of North Philadelphia with high proportions of African American and Latino patients. Temple Clinical Hub created a highly successful organization wherein staff works closely with site investigators and coordinators from multiple disciplines to efficiently execute NETT studies across all sites. Mechanisms that have enhanced the efficiency and quality of research across sites include, for example, the use of a common web-based informatics system developed to safely and quickly identify potential study patients; frequent and regular communication among investigators and coordinators; and diligent site management focused on good clinical research practices and compliance. Over the next five years, the consortium will expand within Philadelphia and across Pennsylvania to improve our reach and to meet the needs of the NETT as a whole. The PHILA-NETT structure is strong and sustainable and yet flexible enough to allow for expansion as needed to carry out the current and anticipated NETT studies. PHILA-NETT investigators have had career-long commitment to research in acute stroke, traumatic brain injury, therapeutic hypothermia and anoxic encephalopathy, all potential areas for NETT studies. These clinician-scientists in adult and pediatric Emergency Medicine, Neurology, Neurosurgery, Trauma, and Neuro-critical care are leaders in their communities and set the standards of care for patients with acute neurological illness and injury. Working with the NETT, the group will execute and design studies to address fundamental research questions. And most important to the mission of Temple University and to the communities in the Commonwealth, we will disseminate information and study results that will serve to guide and advance the treatment of patients with neurological emergencies.

描述（由申请人提供）：Temple University（TU）是费城地区神经系统紧急治疗试验（Phila-Nett）网络的临床枢纽，这是一个社区和学术医疗中心财团，旨在有效地进行与神经急剧有关的临床研究。在过去的四年中，主要地点包括位于北费城低收入地区的TU卫生系统医院和Hahnemann医院，非裔美国人和拉丁裔患者比例很高。 Temple临床中心创建了一个非常成功的组织，其中员工与来自多个学科的现场调查员和协调员紧密合作，以有效地在所有站点进行净研究。增强了跨站点研究效率和质量的机制包括，例如，使用了一种基于Web的常见信息学系统，以安全，快速识别潜在的研究患者；调查人员和协调员之间的频繁和定期沟通；勤奋的现场管理着重于良好的临床研究实践和合规性。在接下来的五年中，该财团将在费城和宾夕法尼亚州范围内扩展，以改善我们的影响力并满足整个篮网的需求。 Phila-Nett结构强大，可持续性，但足够灵活，可以根据需要进行扩展，以进行当前和预期的NetT研究。 Phila-Nett的调查人员对急性中风，脑损伤，治疗性低温和缺氧性脑病的研究都有长期的承诺，这是NETT研究的所有潜在领域。这些临床医生在成人和小儿急诊医学，神经病学，神经外科，创伤和神经关键护理方面是其社区的领导者，并为急性神经系统疾病和受伤的患者设定了护理标准。该小组与Nett合作，将执行和设计研究以解决基本的研究问题。对于坦普尔大学和英联邦社区的任务最重要，我们将传播信息和研究结果，以指导和推进神经系统紧急情况患者的治疗。