PHILA-NETT: Neurological Emergencies Treatment Trials (NETT) Network Clinical Sit

描述(由申请人提供)：坦普尔大学医院(TUH)非常适合作为神经紧急治疗试验(NETT)临床站点中心。作为枢纽，TUH及其三家附属医院，坦普尔儿童医疗中心、东北、圣公会医院和哈内曼大学医院(HH)将组成PHILA-NETT，这是一个有效地进行与神经紧急情况相关的临床研究的联盟。Phila-NETT网站位于费城北部的一个低收入地区，服务于拥有大量非裔美国人和拉丁裔患者的多样化人口。杜克大学是该州最繁忙的创伤中心之一。此外，部分由于其接受来自外部设施的成人和儿科患者的开放政策，以及部分由于费城周围的关键县无法获得神经外科护理，TUH为大量神经科和神经外科紧急情况的患者提供治疗。詹蒂勒博士长期致力于神经急救研究，并积极参与全球缺氧、创伤性脑损伤和中风的翻译和临床研究。在TUH和HH，神经科、神经外科、儿科、创伤、成人和儿科神经危重护理专家提供初级服务，并提供高质量、始终如一的护理。PHILA-NETT计划的核心是一个基于网络的信息学系统。每个参与网站都使用唯一的用户标识来输入患者信息。该系统立即通知研究人员潜在的研究患者和专门的临床研究护士(CRN)，他们非常熟悉不同的研究方案，可以在任何Phila-NETT站点全天候筛查和登记患者。我们的CRN掌握双语，拥有急救护士资格，并接受过神经评估量表方面的广泛培训。正在使用的信息系统将引导数据输入，并将用于向救护车人员、社区医生和重症护理护士提供关于当前最佳实践的反馈。开发一种研究神经紧急情况的协调方法是北费城人的一项财富。由我们的中心和辐射型医院站点服务的社区将获得更高水平的高质量患者护理，并有机会参与尖端神经学研究。此外，Phila-NETT的社区教育部分将侧重于初级和次级疾病预防，以期减少急性神经紧急情况的发生率。

DESCRIPTION (provided by applicant): Temple University Hospital (TUH) is ideally suited to be a Neurological Emergency Treatment Trials (NETT) Clinical Site Hub. As the Hub, TUH with its three satellite hospitals, Temple Children's Medical Center, Northeastern, and Episcopal Hospitals and Hahnemann University Hospital (HUH) will form Phila-NETT, a consortium to effectively perform clinical studies related to neurological emergencies. Located in a low- income area of North Philadelphia, Phila-NETT sites serve a diverse population with a significant number of African American and Latino patients. TUH is one of the busiest Trauma centers in the state. Also, in part due to its open door policy of accepting both adult and pediatric patients from outside facilities and in part to the inaccessibility of Neurosurgical care in key counties surrounding Philadelphia, TUH provides treatment for a tremendous number of patients with neurological and neurosurgical emergencies. Dr. Gentile has had a career-long commitment to neurological emergencies research and has been active in both translational and clinical research in global hypoxia, traumatic brain injury and stroke. At TUH and HUH, specialists in Neurology, Neurosurgery, Pediatrics, Trauma, and adult and pediatric Neuro-critical care have primary services and provide high quality, consistent care. Central to the Phila-NETT program is a web based informatics system. Each participating site uses unique user identification to enter patients' information. The system immediately notifies researchers of potential study patients and dedicated clinical research nurses (CRN), well adept to different study protocols, are available 24/7 to screen and enroll patients at any PHILA-NETT site. Our CRNs bilingual, certified as emergency nurses, and extensively trained in neurologic assessment scales. The informatics system being used will trend data entry and will be used to provide feedback to ambulance personnel, community physicians, and critical care nurses on current best practices. Developing a coordinated approach to the study of neurological emergencies is an asset to the people of North Philadelphia. The communities served by our hub and spoke hospital sites will have access to higher levels of quality patient care and the opportunity to participate in cutting edge neurological research. In addition Phila-NETT's community education component will focus on primary and secondary disease prevention with the hope of decreasing the incidence of acute neurological emergencies.