PHILA-NETT: Neurological Emergencies Treatment Trials (NETT) Network Clinical Sit

描述（由申请人提供）：天普大学医院（TUH）非常适合作为神经紧急治疗试验（NETT）临床站点中心。作为中心，TUH及其三家卫星医院，天普儿童医疗中心，东北医院，圣公会医院和哈内曼大学医院（HUH）将组成Phila-NETT，一个有效开展与神经紧急情况相关的临床研究的联盟。位于费城北部的低收入地区，费城-内特医院为不同人群提供服务，其中包括大量的非洲裔美国人和拉丁裔患者。TUH是该州最繁忙的创伤中心之一。此外，部分由于其接受外部设施的成人和儿科患者的开放政策，部分由于费城周围主要县的神经外科护理难以获得，TUH为大量神经和神经外科急诊患者提供治疗。Gentile博士一直致力于神经急救研究，并积极参与全球缺氧、创伤性脑损伤和中风的转化和临床研究。在TUH和HUH，神经病学、神经外科、儿科、创伤以及成人和儿童神经危重症护理的专家提供初级服务，并提供高质量、持续的护理。Phila-NETT项目的核心是一个基于网络的信息系统。每个参与站点使用唯一的用户标识来输入患者信息。该系统立即通知研究人员潜在的研究患者和专门的临床研究护士（CRN），熟练掌握不同的研究方案，可24/7在任何PHILA-NETT站点筛选和登记患者。我们的crn会说两种语言，获得急救护士的认证，并接受过神经系统评估量表的广泛培训。正在使用的信息系统将趋向数据输入，并将用于向救护人员、社区医生和重症监护护士提供当前最佳做法的反馈。制定协调一致的方法来研究神经紧急情况是北费城人民的财富。我们的中心和放射状医院站点所服务的社区将有机会获得更高水平的高质量患者护理，并有机会参与最前沿的神经学研究。此外，Phila-NETT的社区教育部分将侧重于初级和二级疾病预防，希望减少急性神经紧急情况的发生率。

DESCRIPTION (provided by applicant): Temple University Hospital (TUH) is ideally suited to be a Neurological Emergency Treatment Trials (NETT) Clinical Site Hub. As the Hub, TUH with its three satellite hospitals, Temple Children's Medical Center, Northeastern, and Episcopal Hospitals and Hahnemann University Hospital (HUH) will form Phila-NETT, a consortium to effectively perform clinical studies related to neurological emergencies. Located in a low- income area of North Philadelphia, Phila-NETT sites serve a diverse population with a significant number of African American and Latino patients. TUH is one of the busiest Trauma centers in the state. Also, in part due to its open door policy of accepting both adult and pediatric patients from outside facilities and in part to the inaccessibility of Neurosurgical care in key counties surrounding Philadelphia, TUH provides treatment for a tremendous number of patients with neurological and neurosurgical emergencies. Dr. Gentile has had a career-long commitment to neurological emergencies research and has been active in both translational and clinical research in global hypoxia, traumatic brain injury and stroke. At TUH and HUH, specialists in Neurology, Neurosurgery, Pediatrics, Trauma, and adult and pediatric Neuro-critical care have primary services and provide high quality, consistent care. Central to the Phila-NETT program is a web based informatics system. Each participating site uses unique user identification to enter patients' information. The system immediately notifies researchers of potential study patients and dedicated clinical research nurses (CRN), well adept to different study protocols, are available 24/7 to screen and enroll patients at any PHILA-NETT site. Our CRNs bilingual, certified as emergency nurses, and extensively trained in neurologic assessment scales. The informatics system being used will trend data entry and will be used to provide feedback to ambulance personnel, community physicians, and critical care nurses on current best practices. Developing a coordinated approach to the study of neurological emergencies is an asset to the people of North Philadelphia. The communities served by our hub and spoke hospital sites will have access to higher levels of quality patient care and the opportunity to participate in cutting edge neurological research. In addition Phila-NETT's community education component will focus on primary and secondary disease prevention with the hope of decreasing the incidence of acute neurological emergencies.