Clinical Research Education for Drug Abuse Professionals

描述（由申请人提供）：提交此新申请是为了在贝勒医学院启动药物滥用专业人员临床研究教育（CREDAP）培训计划，该计划基于先前在加州大学洛杉矶分校成功举办的CREDAP。总体目标是提供一个协调、可持续的专门教育和培训基础设施，培养能够开展和传播有关药物依赖及其治疗的临床研究的独立医疗保健专业人员。这一广泛修订的应用程序的特点是可用的导师和研究机会的扩展，包括临床前人类药理学和药物测试（牛顿博士，德拉加尔萨），脑成像和认知神经科学（Moeller博士，莱恩和斯坦伯格），神经遗传学（尼尔森博士），成瘾的神经化学相关性（利特尔博士）和临床试验研究（科斯坦博士）。此外，该方案包括更广泛的机制，确保教师和学员的问责制，目标是不断培养能够成功竞争资金的学员。该计划的具体目标是：1。使学员全面了解药物滥用研究和临床实践，需要在导师的指导下进行为期两年的博士后水平的跨学科临床研究教育和培训。2.教育受训人员有充分的能力，使用适当的调查药物滥用的实验技术，强调先进的技术，程序的可靠性和有效性。3.为了鼓励学员调查药物滥用中定义的临床研究问题，重点是临床试验研究，开始他们的临床研究课程，将持续超过2年的计划。4.通过教他们准备报告值得在同行评审，高质量的生物医学期刊上发表的研究结果的手稿，编写并向NIH提交资助申请，并通过参加会议，研讨会和研讨会成为国家研究社区的一部分，他们可以在那里展示研究，获得新知识，并建立新的合作。5.通过从代表性不足的人群，包括种族/族裔群体和妇女中确定和征求有前途的候选人的申请，增加培训方案的多样性。6.通过正式的评估工作，进一步发展和完善该计划，为可以改进的领域提供投入。

DESCRIPTION (provided by applicant): This new application is submitted to initiate a Clinical Research Education for Drug Abuse Professionals (CREDAP) training program at Baylor College of Medicine, based on the successful CREDAP that was previously sited at UCLA. The overarching goal is to provide a coordinated, sustainable infrastructure of dedicated education and training that will produce independent healthcare professionals capable of conducting and disseminating clinical research pertaining to drug dependence and its treatment. This extensively revised application features an expansion of available mentors and research opportunities to include Pre-Clinical Human Pharmacology and Medications Testing (Drs. Newton, De La Garza), Brain Imaging and Cognitive Neuroscience (Drs. Moeller, Lane, and Steinberg), Neurogenetics (Dr. Nielson), Neurochemical Correlates of Addiction (Dr. Little) and Clinical Trials Research (Dr. Kosten). In addition, the program includes more extensive mechanisms of ensuring accountability of both faculty and trainees with the goal of consistently producing trainees that are able to successfully compete for funding. The specific aims of the program are: 1. to provide trainees with a comprehensive understanding of drug abuse research and clinical practice, entailing interdisciplinary clinical research education and training lasting two years at post-doctoral level under the guidance of preceptors. 2. To educate trainees to have full competence in using experimental techniques appropriate for the investigation of drug abuse, emphasizing advanced technologies, procedural reliability, and validity. 3. To encourage trainees to investigate a defined clinical research issue in drug abuse, with a focus on clinical trials research, starting them on a course of clinical research that will continue beyond the 2-year program. 4. To prepare trainees to become productive clinical researchers by teaching them to prepare manuscripts reporting research results that merit publication in peer-reviewed, high-quality biomedical journals, to write and submit grant applications to the NIH, and to become part of national research communities by attending meetings, seminars, and symposia where they may present research, gain new knowledge, and forge new collaborations. 5. To increase diversity in the training program through identifying and soliciting applications from promising candidates from underrepresented populations, including racial/ethnic groups and women. 6. To further develop and refine the program through formal evaluation efforts that provide input on areas that can be improved.