Aggravating Factors of Asthma in a Rural Environment

农村环境中哮喘的加重因素

• 批准号: 8293169
• 负责人: CATHERINE J KARR
• 金额: $ 29.89万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-24 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8293169
• 关键词: Address; Adult; Affect; Agricultural Workers; Agriculture; Agrochemicals; Animal Feed; Animals; Asthma; Breathing; Cellular Phone; Child; Clinic; Clinical; Collaborations; Communication; Communities; Community Health; Community Health Education; Computer software; Data; Data Collection; Development; Dictyoptera; Dust; Education; Educational Curriculum; Enrollment; Environment; Environmental Risk Factor; Evaluation; Exhalation; Exposure to; Family; Growth; Guidelines; Health; Health Priorities; Hispanics; Home environment; Hour; Humulus; Impact evaluation; Individual; Instruction; Irritants; Livestock; Location; Maps; Measurement; Measures; Molds; Monitor; Morbidity - disease rate; National Heart, Lung, and Blood Institute; Nature; Nitric Oxide; Observational Study; Outcome; Paper; Participant; Patient Self-Report; Patients; Peak Expiratory Flow; Pesticides; Pharmaceutical Preparations; Phase; Pollen; Procedures; Process; Production; Property; Protocols documentation; Provider; Radio; Recording of previous events; Reporting; Role; Rural; Sampling; Severities; Source; Spirometry; Students; Surveys; Symptoms; Telephone; Testing; Time; Tobacco smoke; Training; Translating; Translational Research; United States; Universities; Urban Population; Washington; Work; abstracting; aged; air sampling; airborne allergen; base; chemical allergen; cohort; community organizations; experience; farm worker; innovation; meter; methacholine; outreach; outreach program; peak flow measurement; pollutant; prevent; programs; response; skin prick test; tool; toxicant; trafficking; wasting

Project Abstract Asthma and factors that aggravate asthma in the rural setting are key health priorities identified in an ongoing community-academic partnership, Proyecto Bienestar (PB). This longstanding partnership is a collaboration between the Northwest Community Education Center (NCEC)/KDNA Radio, the Yakima Valley Farm Workers Clinic (YVFWC), Heritage University and the University of Washington (UW). Preventing exacerbations is the most important challenge in asthma treatment and national guidelines recognize the role of indoor environmental factors and traffic-related pollutants. This project addresses an important data gap regarding the role of ambient environmental factors that affect a rural Hispanic population, where asthma morbidity is disproportionately high. In the first phase of the project we will geo- temporally locate episodes of asthma aggravation among a cohort of clinically confirmed asthmatics and utilize geographic information software to map the distribution of agricultural processes that may be responsible for triggering these episodes. The most common suspected ambient triggers will be prioritized. Guided by the timing of the suspected agricultural processes and the reported episodes, sampling with an innovative multi channel sampler will be done with a grid of community-based monitors which will sample air for the suspected aggravators. The asthmatic cohort will continue to be followed into year three. Analysis will focus on concentrations of the suspected triggers which will be compared to reports of new asthma exacerbations by subjects. An educational outreach program based on confirmed and/or strongly suspected aggravators will be developed for delivery through Radio KDNA, the YVFWC and the University of Washington. A clinician training curricula based on management of rural asthmatics will be developed and delivered to the YVFWC clinical providers and their Asthma Outreach Program community health workers. Evaluation will include process evaluation of PB, outcome evaluation of enhanced data collection and asthma management and product quantification including papers, presentations and student participants and impact evaluation of changes community response.

项目摘要 在农村地区，哮喘和哮喘加重的因素是确定的关键卫生优先事项 在一个持续的社区-学术伙伴关系，项目Bienestar（PB）。这场长期的 合作伙伴关系是西北社区教育中心与 （NCEC）/KDNA电台、亚基马山谷农场工人诊所、传统大学 和华盛顿大学（UW）。预防病情加重是最重要的 哮喘治疗的挑战和国家指南认识到室内 环境因素和交通污染物。该项目涉及一个重要数据 关于影响农村西班牙裔人口的周围环境因素的作用的差距， 哮喘发病率高得不成比例。在项目的第一阶段，我们将... 在临床确诊的队列中暂时定位哮喘恶化的发作 并利用地理信息软件绘制农业分布图， 可能引发这些事件的过程。最常见的嫌疑人 将优先考虑环境触发器。根据可疑农业过程的时间安排， 和报告的情节，采样与创新的多通道采样器将完成与 一个以社区为基础的监测网，将对可疑的吸毒者进行空气采样。的 哮喘组群将继续随访至第三年。分析将集中在 可疑触发物的浓度，将与新发哮喘的报告进行比较 受试者的急性加重。一个教育推广计划，根据确认和/或 强烈怀疑的加重剂将通过Radio KDNA、YVFWC进行开发 和华盛顿大学。基于农村基层管理的临床医师培训课程设置 哮喘患者将被开发并交付给YVFWC临床提供者和他们的哮喘 外展方案社区卫生工作者。评价将包括PB的工艺评价， 加强数据收集和哮喘管理及产品的结果评价 量化，包括论文、演示文稿和学生参与者，以及 改变社区反应。