Integrative Environmental Health Sciences Facility Core

综合环境健康科学设施核心

• 批准号: 10165397
• 负责人: CATHERINE J KARR
• 金额: $ 16.9万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10165397
• 关键词: Address; Area; Basic Science; Biomedical Research; Child; Clinical; Clinical Research; Clinical Sciences; Collaborations; Collection; Communities; Consultations; Core Facility; Disasters; Discipline; Disease; Early Diagnosis; Environment; Environmental Health; Environmental Risk Factor; Epigenetic Process; Ethics; Evolution; Fostering; Fred Hutchinson Cancer Research Center; Funding; Funding Opportunities; Genetic; Genomics; Goals; Health; Health Policy; Health Sciences; Human; Individual; Interdisciplinary Study; Leadership; Methods; National Institute of Environmental Health Sciences; Occupational Health; Patients; Physiological; Population Study; Predisposition; Prevention; Public Health; Public Health Schools; Research; Research Design; Research Institute; Research Personnel; Resources; Sampling; Science; Scientist; Services; Structure; Technology; Testing; Time; Translational Research; Universities; Washington; base; catalyst; cohesion; community center; community engaged research; community engagement; data to knowledge; exposed human population; gene environment interaction; health practice; health science research; implementation science; improved; innovation; instrumentation; member; novel; organizational structure; population based; population health; programs; repository; research study; response; translational study; virtual

INTEGRATIVE ENVIRONMENTAL HEALTH SCIENCES FACILITY CORE ABSTRACT The Integrative Environmental Health Sciences Facility Core (IEHS-FC) acts as the navigator for EDGE Center interdisciplinary research. Here, investigators and trainees connect to Center services and a comprehensive consultation resource emphasizing clinical, translational, and population-based studies. The IEHS-FC facilitates Center member research along the translational continuum. Whether the investigator is involved in basic or experimental sciences, clinical studies or observational population-based studies, the IEHS-FC offers high quality advisement, methods, and resources to enhance EHS research, inform public health policy and practice, and impact individual and population health. The IEHS-FC fosters interdisciplinary team science research throughout the University of Washington by integrating basic sciences research with population-based and clinical EHS research to improve early detection and prevention of environmentally related disorders. The Core also helps to identify collaborative opportunities within the greater NIEHS Core Centers program by promoting and connecting researchers to respond to the EHS Core Centers collaborative research funding opportunities. The IEHS-FC is re-structured with two focus areas in addition to the navigator function. The clinical, translational, and population-based studies focus area remains. Investigators will continue to benefit from services covering study design and execution, clinical and physiological testing, collection and storage of human samples, access to controlled-human exposure facilities, and identifying patient groups and sample repositories. In this renewal, new resources are added to support translational research to address emerging needs in Disaster Research Response (DR2), an emerging focus of the Center. This second focus area supports investigators in the conduct of rigorous, timely, ethical, and safe environmental health disaster research response. The IEHS-FC is the gateway for EDGE Center investigators, fostering interdisciplinary and novel EHS research. Its emphasis on clinical and translational sciences, individual susceptibility factors, and gene-environment interactions are in keeping with the goals of NIEHS to maximize the utilization of human population-based studies in EHS research. By offering expert consultation, research services and appropriate referrals to EDGE Center investigators, the IEHS-FC enhances the interconnectedness of the EDGE Center Facility Cores, the Community Engagement Core (CEC), and other EDGE Center components. By leveraging the outstanding resources of the EDGE Center, the Department of Environmental & Occupational Health Sciences, the School of Public Health and the broader UW biomedical research community, the IEHS-FC provides an important and valued hub for NIEHS funded investigators at the UW, the Fred Hutchinson Cancer Research Center, Seattle Children’s Research Institute, the Center’s community partners, and the local, regional, and national EHS research community.

综合环境健康科学核心 摘要 综合环境健康科学设施核心（IEHS-FC）作为EDGE的导航仪 跨学科研究中心。在这里，调查人员和学员连接到中心服务和一个 全面的咨询资源，强调临床，转化和人口为基础的研究。的 IEHS-FC促进了中心成员沿着翻译连续体的研究。无论研究者是 参与基础或实验科学、临床研究或基于人群的观察性研究， IEHS-FC提供高质量的信息，方法和资源，以加强EHS研究，告知公众 卫生政策和做法，并影响个人和人口健康。IEHS-FC促进 跨学科团队科学研究整个华盛顿大学通过整合基本 科学研究与基于人群和临床的EHS研究，以提高早期发现和预防 与环境有关的疾病。该核心还有助于确定 更大的NIEHS核心中心计划，通过促进和连接研究人员，以响应EHS核心 中心合作研究资助的机会。 IEHS-FC的结构进行了调整，除了导航功能外，还有两个重点领域。临床上， 翻译和基于人口的研究重点领域仍然存在。研究人员将继续受益于 服务范围包括研究设计和执行、临床和生理测试、 人类样本、进入受控人类接触设施以及确定患者群体和样本 储存库。在这次更新中，增加了新的资源来支持转化研究，以解决新兴的 灾害研究响应（DR 2）的需求，该中心的一个新的重点。第二个重点领域 支持调查人员进行严格，及时，道德和安全的环境卫生灾难 研究回应。IEHS-FC是EDGE中心研究人员的门户，培养跨学科和 新的EHS研究。它强调临床和转化科学，个体易感因素， 基因-环境相互作用符合NIEHS的目标，即最大限度地利用人类 在EHS研究中以人口为基础的研究。通过提供专家咨询、研究服务和适当的 IEHS-FC通过向EDGE中心研究人员的推荐，增强了EDGE的相互联系 中心设施核心、社区参与核心（CEC）和其他EDGE中心组件。 通过利用EDGE中心的优秀资源，环境与环境部 职业健康科学，公共卫生学院和更广泛的UW生物医学研究 社区，IEHS-FC提供了一个重要的和有价值的枢纽NIEHS资助的研究人员在华盛顿大学， 弗雷德哈钦森癌症研究中心，西雅图儿童研究所，该中心的 社区合作伙伴，以及当地，区域和国家EHS研究社区。