Integrative Environmental Health Sciences Facility Core

综合环境健康科学设施核心 摘要 综合环境健康科学设施核心(IEHS-FC)充当EDGE的导航器 跨学科研究中心。在这里，调查人员和受训人员连接到中心服务和 全面的咨询资源，强调临床、翻译和基于人群的研究。这个 IEHS-FC促进了中心成员在翻译连续体上的研究。无论调查员是 参与基础科学或实验科学、临床研究或观察性人口研究， IEHS-FC提供高质量的建议、方法和资源，以加强EHS研究，告知公众 卫生政策和实践，并影响个人和人口健康。IEHS-FC福斯特 通过整合BASIC在整个华盛顿大学进行跨学科的团队科学研究 以人群为基础的科学研究和临床EHS研究，以改进早期发现和预防 与环境有关的疾病。该核心还有助于在 通过促进和联系研究人员响应EHS核心来实现更大的NIEHS核心中心计划 集中协作研究资助机会。 除了导航器功能外，IEHS-FC还重新构建了两个重点领域。临床上， 翻译和以人口为基础的研究仍然是重点领域。调查人员将继续受益于 服务包括研究设计和实施、临床和生理测试、收集和存储 人体样本，进入受控的人体暴露设施，以及识别患者组和样本 储存库。在这次更新中，添加了新的资源来支持翻译研究，以应对新兴的 灾害研究应对需求(DR2)，这是该中心正在兴起的一个重点。这第二个重点领域 支持调查人员进行严格、及时、合乎道德和安全的环境健康灾难 研究回应。IEHS-FC是EDGE中心调查人员的门户，促进跨学科和 新的EHS研究。它强调临床和翻译科学，个体易感因素，以及 基因与环境的相互作用符合NIEHS最大化利用人类的目标 EHS研究中的基于人口的研究。通过提供专家咨询、研究服务和适当的 推荐给EDGE中心调查人员，IEHS-FC增强了EDGE的互联性 中心设施核心、社区参与核心(CEC)和其他边缘中心组件。 通过利用EDGE中心的杰出资源，环境和环境部 职业健康科学、公共卫生学院和更广泛的华盛顿大学生物医学研究 社区，IEHS-FC为华盛顿大学NIEHS资助的调查人员提供了一个重要和有价值的枢纽， 弗雷德·哈钦森癌症研究中心、西雅图儿童研究所、该中心 社区合作伙伴，以及地方、地区和国家EHS研究社区。

INTEGRATIVE ENVIRONMENTAL HEALTH SCIENCES FACILITY CORE ABSTRACT The Integrative Environmental Health Sciences Facility Core (IEHS-FC) acts as the navigator for EDGE Center interdisciplinary research. Here, investigators and trainees connect to Center services and a comprehensive consultation resource emphasizing clinical, translational, and population-based studies. The IEHS-FC facilitates Center member research along the translational continuum. Whether the investigator is involved in basic or experimental sciences, clinical studies or observational population-based studies, the IEHS-FC offers high quality advisement, methods, and resources to enhance EHS research, inform public health policy and practice, and impact individual and population health. The IEHS-FC fosters interdisciplinary team science research throughout the University of Washington by integrating basic sciences research with population-based and clinical EHS research to improve early detection and prevention of environmentally related disorders. The Core also helps to identify collaborative opportunities within the greater NIEHS Core Centers program by promoting and connecting researchers to respond to the EHS Core Centers collaborative research funding opportunities. The IEHS-FC is re-structured with two focus areas in addition to the navigator function. The clinical, translational, and population-based studies focus area remains. Investigators will continue to benefit from services covering study design and execution, clinical and physiological testing, collection and storage of human samples, access to controlled-human exposure facilities, and identifying patient groups and sample repositories. In this renewal, new resources are added to support translational research to address emerging needs in Disaster Research Response (DR2), an emerging focus of the Center. This second focus area supports investigators in the conduct of rigorous, timely, ethical, and safe environmental health disaster research response. The IEHS-FC is the gateway for EDGE Center investigators, fostering interdisciplinary and novel EHS research. Its emphasis on clinical and translational sciences, individual susceptibility factors, and gene-environment interactions are in keeping with the goals of NIEHS to maximize the utilization of human population-based studies in EHS research. By offering expert consultation, research services and appropriate referrals to EDGE Center investigators, the IEHS-FC enhances the interconnectedness of the EDGE Center Facility Cores, the Community Engagement Core (CEC), and other EDGE Center components. By leveraging the outstanding resources of the EDGE Center, the Department of Environmental & Occupational Health Sciences, the School of Public Health and the broader UW biomedical research community, the IEHS-FC provides an important and valued hub for NIEHS funded investigators at the UW, the Fred Hutchinson Cancer Research Center, Seattle Children’s Research Institute, the Center’s community partners, and the local, regional, and national EHS research community.