Training Attentional Awareness and Control in ADHD

训练注意力缺陷多动症的注意力意识和控制

• 批准号: 8597235
• 负责人: GREGORY V SIMPSON
• 金额: $ 39.97万
• 依托单位: THINK NOW, INC.
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-02 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8597235
• 关键词: Address; Adult; Attention; Attention deficit hyperactivity disorder; Awareness; Back; Behavior; Behavioral; Brain; Businesses; Clinical; Code; Cognitive; Collaborations; Control Groups; Data; Databases; Development; Devices; Disease; Educational process of instructing; Entrepreneurship; Exercise; Failure; Feeds; Feeling; Foundations; Funding; Glosso-Sterandryl; Goals; Grant; Guidelines; Individual; Information Systems; Internet; Learning; Legal patent; Life; Link; Medical Device; Methods; Mind; Modeling; Muscle; Online Systems; Outcome; Outcome Measure; Ownership; Performance; Phase; Randomized; Randomized Controlled Trials; Reading; Research; Schools; Science; Signal Transduction; Software Design; Symptoms; System; Techniques; Training; Translating; United States National Institutes of Health; base; brain research; cost; design; distraction; economic impact; efficacy testing; improved; inattention; innovation; lecturer; member; mind control; neurophysiology; programs; public health relevance; resilience; skills; success; tool; web site

DESCRIPTION (provided by applicant): Attention-Deficit/Hyperactivity Disorder (ADHD) is a highly prevalent disorder, incurring billions of dollars of costs annually, for which there is a rel need for additional non-pharmacologic treatments. Deficits in maintaining attentional control manifest as inconsistent intra-individual performance on sustained attention tasks with periods of normal performance and other periods of poor performance thought to reflect "inattention", and is considered by several groups to be an important component of ADHD. Research by our team members on the behavioral and neurophysiological bases of sustaining attentional control reveal infra-slow fluctuations in performance and in brain signals related to sustained attention to targets, suppression of distractors and mind wandering. We have created an innovative (patent pending) product that directly targets these three components of sustained attentional control in ADHD. The Sustained Attentional Control (SAC) training utilizes the ubiquity of mobile-apps to train adults with ADHD in all contexts of real life. Our approach combines building attentional control skills with awareness of attentional control and includes active transfer of the experiential sense of three attentional control components to real life activities (sustained focus, suppression of distractions and mind wandering). This Phase-I project is aimed at demonstrating the efficacy of the SAC product for training sustained attentional control in adults with ADHD. In Aim-1 we build on the existing code framework of our current apps and the back-end data system, to complete the programming and artwork for the remaining set of training apps and optimize them for adults with ADHD. In Aim-2 we test the efficacy of SAC training - 100 subjects will be randomly assigned to either a Treatment Condition (SAC training), or Control Condition with equivalent app usage and contact, but without factors hypothesized to provide training benefits. We will determine the amount of improvement between Pre- and Post- Training in each condition and compare these improvements between Treatment and Control conditions using behavioral and neurophysiological outcome measures.

描述（由申请人提供）：注意力缺陷/多动症（ADHD）是一种高度普遍的疾病，每年会产生数十亿美元的成本，因此需要进行其他非药物治疗。保持注意力控制的缺陷表现为持续的注意任务上的个体内部表现不一致，正常表现和其他绩效不佳时期被认为反映了“注意力不集中”，并且被几个小组视为ADHD的重要组成部分。我们的团队成员就维持注意力控制的行为和神经生理基础的研究揭示了与持续关注目标，抑制分心者和思维徘徊有关的性能和大脑信号中的基础流动波动。我们创建了一种创新的（专利）产品，该产品直接针对ADHD中持续注意力控制的这三个组成部分。持续的注意力控制（SAC）培训利用移动应用程序的普遍存在在现实生活的各种情况下培训了具有多动症的成年人。我们的方法结合了构建注意力控制技能和注意力控制的意识，包括将三种注意力控制组件的经验感积极转移到现实生活中（持续的重点，抑制分心和思维徘徊）。该阶段I项目旨在证明SAC产品在患有多动症的成年人中训练持续注意力控制的功效。在AIM-1中，我们以当前应用程序和后端数据系统的现有代码框架为基础，以完成其余一组培训应用程序的编程和艺术品，并为患有ADHD的成年人优化它们。在AIM -2中，我们测试SAC培训的功效-100名受试者将随机分配给治疗条件（SAC培训），或具有同等应用程序使用和接触的控制条件，但没有假设提供培训益处的因素。我们将通过行为和神经生理结局指标确定在每种情况下训练前和训练之间的改善量，并比较治疗和控制条件之间的这些改善。