Understanding Antiretroviral Therapy Uptake Behaviors in Tanzania and Thailand

了解坦桑尼亚和泰国的抗逆转录病毒治疗接受行为

• 批准号: 8423329
• 负责人: Pammie Renee Crawford
• 金额: $ 3.87万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-02-08 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8423329
• 关键词: AIDS prevention; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Advanced Development; Affect; Africa; Africa South of the Sahara; Anti-Retroviral Agents; Attention; Awareness; Behavior; Behavior Therapy; Belief; Clinic; Communities; Counseling; Country; Data; Educational Intervention; Epidemic; Ethnography; Future; Goals; HIV; HIV prevention trial; HIV risk; Health; Health Communication; Health behavior; Health education; Health system; Human immunodeficiency virus test; Income; Intervention; Interview; Knowledge; Lead; Life; Longitudinal Studies; Mission; National Institute of Mental Health; Perception; Pharmacotherapy; Phase; Population; Public Health; Randomized; Randomized Controlled Trials; Research; Research Support; Risk Behaviors; Tanzania; Testing; Thailand; Time; Tribes; World Health Organization; antiretroviral therapy; base; cohort; fight against; improved; interest; knowledge base; prevent; research study; transmission process; uptake

DESCRIPTION (provided by applicant): The proposed study is nested within Project Accept, a NIMH-sponsored Phase III Randomized Controlled Trial in Sub-Saharan Africa and Thailand. PA is an HIV prevention trial in which communities in Africa and Thailand were randomized to receive: a community-based HIV voluntary counseling and testing intervention plus standard clinic-based VCT (SVCT), or SVCT alone. The purpose of the proposed health research is to better understand beliefs, perceptions, awareness and knowledge of ART affecting: uptake of ART, uptake of HIV testing, and influence on HIV risk behaviors in Thai and Tanzanian study communities. Utilizing Project Accept data for this research study, the following long-term study objectives will be achieved: 1) determine knowledge and information gaps obstructing ART uptake, 2) understand influence of ART availability on HIV risk behaviors, and 3) expand the knowledge base of behaviors surrounding ART uptake in Thai and Tanzanian study communities. Specific study aims are to: 1) Understand ART perceptions, beliefs and awareness in Intervention vs. Comparison Communities in Thailand and Tanzania, 2) Assess the impact of the Project Accept Intervention on ART knowledge and awareness of ART availability in Thai and Tanzanian health systems, 3) Determine how ART influences HIV risk behaviors in Thailand and Tanzania. Project Accept qualitative data from ethnographic studies in Tanzania and Thailand are rich in information surrounding ART perceptions, knowledge and beliefs. In-depth interviews conducted with intervention and comparison community cohorts at the following Project Accept intervention times (baseline, 6-months, 15- months, and 30-months) will be analyzed to answer the research questions and achieve the study aims. The proposed study is highly relevant to a NIMH mission objective: strengthening the public health impact of NIMH-support research, in particular research that develops and disseminates behavioral interventions that prevent HIV/AIDS transmission. By understanding the perceptions, knowledge, awareness and beliefs of ART in Tanzania and Thailand, behavioral interventions that prevent HIV/AIDS transmission (one of the objectives of NIMH's Division of AIDS and Health and Behavior Research) can be further developed and disseminated in the respective regions.

描述（由申请人提供）：拟议的研究嵌套在项目接受中，在撒哈拉以南非洲和泰国进行了NIMH赞助的III期随机对照试验。 PA是一项艾滋病毒预防试验，在非洲和泰国的社区被随机接受：基于社区的艾滋病毒自愿咨询和测试干预以及基于标准的诊所的VCT（SVCT）或SVCT。拟议的健康研究的目的是更好地了解影响艺术的信念，看法，意识和知识：对艺术的吸收，对艾滋病毒测试的吸收以及对泰国和坦桑尼亚研究社区中艾滋病毒风险行为的影响。利用项目接受这项研究的研究数据，将实现以下长期研究目标：1）确定阻碍艺术吸收的知识和信息差距，2）了解艺术可用性对艾滋病毒风险行为的影响，3）扩大泰国和坦桑尼亚研究社区围绕艺术吸收的行为知识的知识基础。具体研究的目的是：1）了解干预措施与泰国和坦桑尼亚的比较社区的艺术感知，信念和意识，2）评估项目的影响接受干预对泰国和坦桑尼亚卫生系统中艺术知识的意识以及对泰国卫生系统中艺术可用性的认识，3）确定艺术影响泰国和泰国坦桑山的艾滋病毒风险行为。项目接受坦桑尼亚和泰国人种学研究的定性数据丰富围绕艺术观念，知识和信念的信息。将在以下项目接受干预时间（基线，6个月，15个月和30个月）进行干预和比较社区人群进行的深入访谈，以回答研究问题并实现研究目标。拟议的研究与NIMH任务目标高度相关：加强NIMH-Sup-P-P-Support研究的公共卫生影响，特别是开发和传播行为干预措施以防止HIV/AIDS传播的研究。通过了解坦桑尼亚和泰国艺术对艺术的看法，知识，意识和信念，可以进一步发展并在各自的地区进行进一步发展和传播，这些行为干预措施可以进一步发展，并可以进一步发展和传播。