High-Performance High-Field Parallel MRI

描述(由申请人提供)： 在这个持续的项目中，我们团队的目标是开发和部署用于高性能高场磁共振成像的新型远程环绕多元素发射器和探测器阵列结构。虽然传统的观点认为应该采用贴合的身体轮廓线圈，但我们计划建造的新结构将消除贴合多元素阵列的许多实际和基本缺点，同时保留所有自由度，并通过包括在高磁场强度下具有独特益处的新型射频场元素来增强成像性能。在构建了3特斯拉和7特斯拉手术的几个原型后，我们将展示这种新的“非接触式”图像采集技术的潜在好处，无论是单独使用还是与目标局部线圈结合使用，都可以可视化胰腺癌和髋骨关节炎等疾病过程，这些过程已被证明是传统MRI方法的挑战。这项持续的工作是在R01项目成功的第一个资助期之后进行的，该项目向快速核磁共振领域引入了广泛的技术和方法创新。

DESCRIPTION (provided by applicant): In this continuing project, our team aims to develop and deploy novel remote encircling many-element transmitter and detector array structures for high-performance high-field magnetic resonance imaging. Whereas conventional wisdom argues for close-fitting body-contoured coils, the new structures we plan to build will eliminate the many practical and fundamental disadvantages of close-fitting many-element arrays, while preserving all degrees of freedom, and enhancing imaging performance through the inclusion of novel RF field elements of unique benefit at high magnetic field strength. After constructing several prototypes for 3 Tesla and 7 Tesla operation, we will demonstrate potential benefits of this new "contact-free" image acquisition technology, whether alone or in combination with targeted local coils, for visualization of disease processes such as pancreatic cancer and hip osteoarthritis, which have proven to be a challenge for traditional MRI approaches. This continuing work follows the successful first funding period of an R01 project which introduced a wide range of technological and methodological innovations to the field of rapid MRI.