Center for Advanced Imaging Innovation and Research (CAI2R)

描述：高级成像创新与研究中心(CAI2R)结合了三个领域的新型和高影响力成像技术开发，以及一个独特的跨部门和学术-产业合作的新模式，旨在快速有效地将该技术转化为临床实践。即将开发的技术围绕快速、连续和全面的数据采集以及灵活的图像重建这一新范式展开，这将影响和连接包括磁共振成像(MRI)和正电子发射断层扫描(PET)在内的多种成像方式。技术研究与开发(TR&D)项目1旨在对成像时间进行新的利用，采用前沿的快速图像采集和高级图像重建方法，用包含关于多个互补对比度和不同动态的丰富信息的简单、全面的体积采集来取代传统的复杂、有针对性和低效的成像协议。研发#2设想了射频(RF)领域的新的和改进的用途，为射频设计、MRI的安全和控制提供了新的工具，并将研发#1开发的快速连续采集方法的覆盖范围扩展到高性能高场应用。研发#3致力于同步的新用途，通过协同同时采集和联合重建提高MR和PET的基本能力。我们的中心有一个独特而明确的翻译重点，这反映在研发项目的日常运作以及合作项目(CPS)和服务项目(SPS)的主题上，这些项目侧重于对公共健康影响较大的三个一般领域：癌症、肌肉骨骼疾病和神经系统疾病。 为了与这一翻译重点保持一致，CAI2R还受到一种新的协作模式的推动，在这种模式中，基础科学家、临床医生和行业开发人员定期坐在一起 扫描仪和阅览室，用于互动技术开发和评估。这种跨学科协作模式也为我们的培训活动提供了信息，其中许多活动都是针对成功的翻译研究团队的组建和运作而进行的。同时，在临床利益相关者和行业合作伙伴的早期参与下，我们的目标是使CAI2R技术广泛用于临床和研究。我们在CAI2R中最广泛的目标是改变MR和PET的数据采集、图像重建和日常扫描的模式，以促进生物医学知识的发展，并造福于患者和护理他们的医生。

DESCRIPTION: The Center for Advanced Imaging Innovation and Research (CAI2R) combines three areas of novel and high-impact imaging technology development with a unique new model for interdepartmental and academic-industrial collaboration aimed at translating that technology rapidly and effectively into clinical practice. The technologies to be developed center around a new paradigm of rapid, continuous, and comprehensive data acquisition, together with flexible image reconstruction, which will affect and connect multiple imaging modalities, including magnetic resonance imaging (MRI) and Positron Emission Tomography (PET). Technology Research and Development (TR&D) project #1 aims at a new use of time in imaging, deploying leading-edge methods of rapid image acquisition and advanced image reconstruction to replace traditional complex, targeted, and inefficient imaging protocols with simple, comprehensive, volumetric acquisitions that contain rich information about multiple complementary contrasts and diverse dynamics. TR&D #2 envisions new and improved uses for radiofrequency (RF) fields, providing new tools for RF design, safety and control in MRI, and expanding the reach of the rapid continuous acquisition approach developed in TR&D #1 to high-performance high-field applications. TR&D #3 is addressed at new uses of simultaneity, advancing the fundamental capabilities of MR and PET through synergistic simultaneous acquisition and joint reconstruction. Our Center has a unique and explicit translational focus, which is reflected in the day-to-day operation of TR&D projects as well as in the topics of Collaborative Projects (CPs) and Service Projects (SPs), which are focused on three general areas of high public health impact: cancer, musculoskeletal disease, and neurologic disease. In keeping with this translational emphasis, CAI2R is also be driven by a novel collaboration model in which basic scientists, clinicians, and industry developers sit down together regularly at the scanners and in reading rooms for interactive technology development and assessment. This interdisciplinary collaboration model also informs our Training activities, many of which are addressed at the formation and operation of successful translational research teams. Meanwhile, with early involvement of clinical stakeholders and industry partners, we aim to make CAI2R technologies widely available for clinical and research use. Our broadest goal in CAI2R is to change the paradigms of data acquisition, image reconstruction, and day-to-day scanning for MR and PET, for the advancement of biomedical knowledge and for the benefit of patients and the physicians who care for them.