Center for Advanced Imaging Innovation and Research (CAI2R)

描述：先进成像创新和研究中心（CAI2R）结合了三个领域的新颖和高影响力的成像技术的发展与独特的跨部门和学术-工业合作的新模式，旨在将该技术快速有效地转化为临床实践。这些技术将围绕快速、连续和全面的数据采集以及灵活的图像重建的新范式进行开发，这将影响和连接多种成像方式，包括磁共振成像（MRI）和正电子发射断层扫描（PET）。技术研发（TR&D）项目#1旨在成像中的新时间利用，部署快速图像采集和先进图像重建的前沿方法，以简单，全面，体积采集取代传统的复杂，有针对性和低效的成像协议，其中包含有关多个互补对比和不同动态的丰富信息。TR&D #2设想了射频（RF）领域的新的和改进的用途，为MRI中的RF设计，安全和控制提供了新的工具，并将TR&D #1中开发的快速连续采集方法的范围扩展到高性能高场应用。TR&D #3解决了同时性的新用途，通过协同同时采集和联合重建来提高MR和PET的基本能力。我们的中心有一个独特而明确的翻译重点，这反映在研发项目的日常运作以及合作项目（CPs）和服务项目（SPs）的主题上，这些项目集中在三个对公共卫生有高影响的一般领域：癌症、肌肉骨骼疾病和神经系统疾病。

DESCRIPTION: The Center for Advanced Imaging Innovation and Research (CAI2R) combines three areas of novel and high-impact imaging technology development with a unique new model for interdepartmental and academic-industrial collaboration aimed at translating that technology rapidly and effectively into clinical practice. The technologies to be developed center around a new paradigm of rapid, continuous, and comprehensive data acquisition, together with flexible image reconstruction, which will affect and connect multiple imaging modalities, including magnetic resonance imaging (MRI) and Positron Emission Tomography (PET). Technology Research and Development (TR&D) project #1 aims at a new use of time in imaging, deploying leading-edge methods of rapid image acquisition and advanced image reconstruction to replace traditional complex, targeted, and inefficient imaging protocols with simple, comprehensive, volumetric acquisitions that contain rich information about multiple complementary contrasts and diverse dynamics. TR&D #2 envisions new and improved uses for radiofrequency (RF) fields, providing new tools for RF design, safety and control in MRI, and expanding the reach of the rapid continuous acquisition approach developed in TR&D #1 to high-performance high-field applications. TR&D #3 is addressed at new uses of simultaneity, advancing the fundamental capabilities of MR and PET through synergistic simultaneous acquisition and joint reconstruction. Our Center has a unique and explicit translational focus, which is reflected in the day-to-day operation of TR&D projects as well as in the topics of Collaborative Projects (CPs) and Service Projects (SPs), which are focused on three general areas of high public health impact: cancer, musculoskeletal disease, and neurologic disease. In keeping with this translational emphasis, CAI2R is also be driven by a novel collaboration model in which basic scientists, clinicians, and industry developers sit down together regularly at the scanners and in reading rooms for interactive technology development and assessment. This interdisciplinary collaboration model also informs our Training activities, many of which are addressed at the formation and operation of successful translational research teams. Meanwhile, with early involvement of clinical stakeholders and industry partners, we aim to make CAI2R technologies widely available for clinical and research use. Our broadest goal in CAI2R is to change the paradigms of data acquisition, image reconstruction, and day-to-day scanning for MR and PET, for the advancement of biomedical knowledge and for the benefit of patients and the physicians who care for them.