Positive Emotional Processing: Exploring Novel Treatment Targets in Social Phobia
Positive Emotional Processing: Exploring Novel Treatment Targets in Social Phobia
批准号:
8580673
负责人:
Charles Taylor
金额:
$22.73万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-01-01 至 2016-05-31
关键词:
AddressAffectAffectiveAnxietyAnxiety DisordersAttenuatedBehaviorBehavioralBrainBrain regionCognitionCognitiveControl GroupsCorpus striatum structureCuesDiagnosisDiagnosticEmotionalEmotionsEvaluationFrightFunctional Magnetic Resonance ImagingGeneralized Anxiety DisorderGoalsImpairmentIndividualInterventionLaboratoriesModelingModificationMorbidity - disease rateMotivationNeurosciencesParticipantPatientsPersonal SatisfactionPhasePositioning AttributeProceduresProcessPublic HealthQuality of lifeRecoveryRelative (related person)ReportingResearchRewardsRiskServicesSocial FunctioningSocial InteractionSocial PhobiaSocial isolationStimulusStructureSymptomsSystemTestingTrainingWorkaffective neuroscienceapproach behavioravoidance behaviorbasecaudate nucleuscognitive neurosciencecomputerizedcostdesignemotional experienceexperienceimprovedindexinglearning extinctionmeetingsmortalityneuroimagingnovelprimary outcomepsychologicpsychosocialputamenrelating to nervous systemresponsereward processingsocialsocial cognitiontreatment response
中文摘要
社交焦虑障碍(SAD)是一种非常普遍且使人衰弱的疾病,其特征是显著的
英文摘要
Social anxiety disorder (SAD) is a highly prevalent and debilitating condition, marked by significant
impairments in social relationship functioning and a diminished quality of life. Current treatment approaches
for SAD emphasize heightened negative emotions (anxiety and fear), cognitions (preoccupation with
negative evaluation), and avoidance behaviors as the central treatment targets. However, these treatments
are removed from research suggesting that SAD is also characterized by a dysregulation of basic regulatory
systems that govern responses to positive stimuli and situations with reward potential. Although currently
available treatments for SAD are efficacious, many individuals fail to achieve full recovery and continue to
experience impairments in positive social functioning following treatment. These deficiencies are notable
given that positive social and emotional experiences are fundamental for psychological and physical wellbeing.
To address this critical gap, the proposed project will combine a cognitive neuroscience-informed
experimental procedure (cognitive bias modification, CBM)^with functioning neuroimaging to investigate how
modifying implicit approach tendencies for positive social cues effects behavioral, affective, and brain
mechanisms that are important for positive social relationships and well-being. Work accomplished by the
applicant during the K99 phase demonstrated that (1) an approach/avoidance CBM procedure reliably
modifies implicit approach tendencies and influences indices of positive social functioning in the latxiratory,
and (2) CBM procedures modulate functioning in brain regions that are important for emotion processing.
Building on these studies, the specific aims of this proposal are:. (1) To examine the effects of a brief multisession
approach-positive CBM procedure on change in positive affect and social approach behaviors in
individuals meeting diagnostic criteria for generalized SAD; (2) To examine the neural correlates of social
reward processing in GSAD relative to healthy controls; and (3) To examine functional changes in reward
neurodrcuitry following the approach-positive CBM procedure: The goal of this project is to identify novel
treatment targets and approaches that can augment existing interventions in GSAD patients.
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会议论文
Novel Behavioral Intervention to Target Social Reward Sensitivity and Attachment
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批准号:10240445
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项目类别:
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资助金额:$72.33万
-
财政年份:2017
-
负责人:Charles Taylor
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依托单位:
Novel Behavioral Intervention to Target Social Reward Sensitivity and Attachment
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批准号:10596778
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项目类别:
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资助金额:$7.51万
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财政年份:2017
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负责人:Charles Taylor
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依托单位:
Novel Behavioral Intervention to Target Social Reward Sensitivity and Attachment
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批准号:9373740
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项目类别:
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资助金额:$74.82万
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财政年份:2017
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负责人:Charles Taylor
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依托单位:
Novel Behavioral Intervention to Target Social Reward Sensitivity and Attachment
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批准号:10460269
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项目类别:
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资助金额:$69.68万
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财政年份:2017
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负责人:Charles Taylor
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依托单位:
Positive Emotional Processing: Exploring Novel Treatment Targets in Social Phobia
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批准号:8208994
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项目类别:
-
资助金额:$8.95万
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财政年份:2011
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负责人:Charles Taylor
-
依托单位:
Positive Emotional Processing: Exploring Novel Treatment Targets in Social Phobia
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批准号:8885895
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项目类别:
-
资助金额:$21.13万
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财政年份:2011
-
负责人:Charles Taylor
-
依托单位:
Positive Emotional Processing: Exploring Novel Treatment Targets in Social Phobia
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批准号:8046838
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项目类别:
-
资助金额:$9.0万
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财政年份:2011
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负责人:Charles Taylor
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依托单位:
海外基金