IGF::OT::IGF MANAGEMENT OF THE PRIMATE AGING DATABASE (PAD)

IGF::OT::IGF 灵长类衰老数据库 (PAD) 管理

• 批准号: 8738221
• 负责人: Joseph W. Kemnitz
• 金额: $ 10.58万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8738221
• 关键词: Aging; Aging-Related Process; Animals; Biological; Biological Markers; Blood Chemical Analysis; Body Composition; Communities; Data; Databases; Elderly; Individual; Institution; Longevity; Macaca mulatta; Measurement; Pathology; Primates; Research; Research Personnel; age related; nonhuman primate; normal aging; species difference; trait

This is a searchable database developed to allow analysis of age-related traits in non-human primates (NHP). Currently, the database contains data from 20 species at 11 different institutions, comprising over 3000 individual animals and 500,000 data points. About 80% of the data is from rhesus monkeys. Current data fields are primarily lifespan, body composition parameters, and blood chemistry parameters, although addition of other parameters is possible. The PAD is useful for analyses of species differences in normal aging processes, studies on biomarkers of normal aging and age-related pathologies, and determination of baseline levels in geriatric NHP colonies.

这是一个可搜索的数据库，用于分析非人灵长类动物（NHP）的年龄相关特征。目前，该数据库包含来自11个不同机构的20个物种的数据，包括3000多只动物和50万个数据点。大约80%的数据来自恒河猴。目前的数据字段主要是寿命、身体成分参数和血液化学参数，尽管可能会添加其他参数。PAD可用于分析正常衰老过程中的物种差异，研究正常衰老和年龄相关病理的生物标志物，以及确定老年NHP菌落的基线水平。