WEB PORTAL FOR NONHUMAN PRIMATE RESEARCH MODELS

非人类灵长类动物研究模型门户网站

• 批准号: 8359545
• 负责人: Joseph W. Kemnitz
• 金额: $ 45.49万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8359545
• 关键词: AIDS/HIV problem; Adoption; Aging; Animals; Area; Behavioral Research; Biomedical Research; Clinical Sciences; Collaborations; Communicable Diseases; DNA Library; Data; Development; Disease; Funding; Funding Opportunities; Health; Human; Immunologic Tests; Information Services; Information Technology; Institutes; Internet; Link; Metabolic Diseases; Methods; Modeling; National Center for Research Resources; Neurosciences; Performance; Primates; Process; Reagent; Regenerative Medicine; Reproduction; Research; Research Personnel; Resources; Services; Specific Pathogen Frees; Stem cells; Testing; Tissue Banking; Tissue Banks; Translational Research; Wisconsin; Work; data sharing; germ free condition; nonhuman primate; programs; public health relevance; working group

DESCRIPTION (provided by applicant): The proposed project will establish a comprehensive web portal into Information pertaining to the use on nonhuman primates (NHR) in biomedical and translational research. The types of information to be linked through this "PrimatePortal" will include publicly funded resources providing access to the NHP themselves, as well as methods and facilities for specialized characterization of the animals in a research context. PrimatePortal will also provide links describing particular NHP models for human health and disease, tissue and DNA banks for NHP material and bibliographic data on previous research. In the first year of the project the emphasis will be on organizing and linking information pertaining to HIV/AIDS research, such as availability of specific pathogen-free NHP, resources for virological and immunologic testing, specialized reagents and other testing services, and funding opportunities for this research. In the second and third years the scope of PrimatePortal will be expanded to other areas of research, such as other infectious diseases, reproduction and development (including stem cells and regenerative medicine), aging, metabolic diseases, and neurosciences and behavioral research. The current activities of the Working Groups in the consortium of National Primate Research Centers (NPRCs) will be incorporated into PrimatePortal. The proposed work builds on initiatives in information technology and provision of information services, as well as data sharing and adoption of best practices, promoted by the Wisconsin National Primate Research Center in collaboration with other NPRCs and NCRR-supported NHP resources, as well as new programs through linkage with Clinical and Translational Science Institutes. PUBLIC HEALTH RELEVANCE (provided by applicant): The proposed project will facilitate the process of basic biomedical and translational research by enhancing the availability of information regarding the investigational use of nonhuman primates (NHP). Through the use of PrimatePortal, researchers will be able to acquire critical information regarding the appropriateness, availability and performance of studies benefiting from the use of NHP models.

描述（由申请人提供）：拟议项目将建立一个综合门户网站，提供有关在生物医学和转化研究中使用非人类灵长类动物（NHR）的信息。通过这个“灵长类门户网站”链接的信息类型将包括提供访问 NHP 本身的公共资助资源，以及在研究背景下对动物进行专门表征的方法和设施。 PrimatePortal 还将提供描述人类健康和疾病的特定 NHP 模型、NHP 材料的组织和 DNA 库以及先前研究的书目数据的链接。该项目第一年的重点将是组织和链接与艾滋病毒/艾滋病研究有关的信息，例如无特定病原体的 NHP 的可用性、病毒学和免疫学检测资源、专门试剂和其他检测服务以及本研究的资助机会。在第二年和第三年，PrimatePortal的范围将扩展到其他研究领域，例如其他传染病、生殖和发育（包括干细胞和再生医学）、衰老、代谢疾病以及神经科学和行为研究。国家灵长类研究中心 (NPRC) 联盟工作组当前的活动将纳入 PrimatePortal。拟议的工作建立在威斯康星州国家灵长类研究中心与其他 NPRC 和 NCRR 支持的 NHP 资源合作推动的信息技术和信息服务提供以及数据共享和采用最佳实践的举措以及通过与临床和转化科学研究所联系的新计划的基础上。 公共卫生相关性（由申请人提供）：拟议项目将通过提高有关非人类灵长类动物（NHP）研究用途的信息的可用性，促进基础生物医学和转化研究的进程。通过使用 PrimatePortal，研究人员将能够获得有关受益于 NHP 模型的研究的适当性、可用性和绩效的关键信息。