WEB PORTAL FOR NONHUMAN PRIMATE RESEARCH MODELS

非人类灵长类动物研究模型门户网站

• 批准号: 8359545
• 负责人: Joseph W. Kemnitz
• 金额: $ 45.49万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8359545
• 关键词: AIDS/HIV problem; Adoption; Aging; Animals; Area; Behavioral Research; Biomedical Research; Clinical Sciences; Collaborations; Communicable Diseases; DNA Library; Data; Development; Disease; Funding; Funding Opportunities; Health; Human; Immunologic Tests; Information Services; Information Technology; Institutes; Internet; Link; Metabolic Diseases; Methods; Modeling; National Center for Research Resources; Neurosciences; Performance; Primates; Process; Reagent; Regenerative Medicine; Reproduction; Research; Research Personnel; Resources; Services; Specific Pathogen Frees; Stem cells; Testing; Tissue Banking; Tissue Banks; Translational Research; Wisconsin; Work; data sharing; germ free condition; nonhuman primate; programs; public health relevance; working group

DESCRIPTION (provided by applicant): The proposed project will establish a comprehensive web portal into Information pertaining to the use on nonhuman primates (NHR) in biomedical and translational research. The types of information to be linked through this "PrimatePortal" will include publicly funded resources providing access to the NHP themselves, as well as methods and facilities for specialized characterization of the animals in a research context. PrimatePortal will also provide links describing particular NHP models for human health and disease, tissue and DNA banks for NHP material and bibliographic data on previous research. In the first year of the project the emphasis will be on organizing and linking information pertaining to HIV/AIDS research, such as availability of specific pathogen-free NHP, resources for virological and immunologic testing, specialized reagents and other testing services, and funding opportunities for this research. In the second and third years the scope of PrimatePortal will be expanded to other areas of research, such as other infectious diseases, reproduction and development (including stem cells and regenerative medicine), aging, metabolic diseases, and neurosciences and behavioral research. The current activities of the Working Groups in the consortium of National Primate Research Centers (NPRCs) will be incorporated into PrimatePortal. The proposed work builds on initiatives in information technology and provision of information services, as well as data sharing and adoption of best practices, promoted by the Wisconsin National Primate Research Center in collaboration with other NPRCs and NCRR-supported NHP resources, as well as new programs through linkage with Clinical and Translational Science Institutes. PUBLIC HEALTH RELEVANCE (provided by applicant): The proposed project will facilitate the process of basic biomedical and translational research by enhancing the availability of information regarding the investigational use of nonhuman primates (NHP). Through the use of PrimatePortal, researchers will be able to acquire critical information regarding the appropriateness, availability and performance of studies benefiting from the use of NHP models.

描述（由申请人提供）：拟议的项目将在生物医学和转化研究中建立与非人类灵长类动物（NHR）有关的信息。通过这种“灵长类运动”链接的信息类型将包括提供对NHP本身访问权限的公共资助资源，以及在研究环境中对动物进行专业表征的方法和设施。 PremimatePortal还将提供链接，描述针对人类健康和疾病，组织和DNA库的特定NHP模型，用于NHP材料以及先前研究的书目数据。在该项目的第一年，重点将是组织和联系与HIV/AIDS研究有关的信息，例如可用性的无病原体NHP，病毒学和免疫学测试资源，专门的试剂和其他测试服务以及这项研究的资金机会。在第二年和第三年中，灵长类运动的范围将扩展到其他研究领域，例如其他传染病，繁殖和发育（包括干细胞和再生医学），衰老，代谢疾病以及神经科学和行为研究。在国家灵长类动物研究中心（NPRC）联盟中，工作组的当前活动将纳入灵长类阶段。拟议的工作建立在信息技术和信息服务方面的举措以及数据共享和采用最佳实践的基础上，由威斯康星州国家灵长类动物研究中心与其他NPRCS和NCRR支持的NHP资源合作推广，并通过与临床和转换科学学院进行链接。 公共卫生相关性（由申请人提供）：拟议的项目将通过增强有关非人类灵长类动物（NHP）的研究信息的可用性来促进基本生物医学和转化研究的过程。通过使用PrimatePortal，研究人员将能够获取有关从使用NHP模型中受益的研究的适当性，可用性和绩效的关键信息。