STEM CELL & REGENERATIVE MEDICINE CENTER NONHUMAN PRIMATES CORE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的：在进行人体试验之前，测试基于干细胞的治疗方法的有效性并评估其可能的副作用。 这项服务始于2007年7月，当时华盛顿大学麦迪逊分校成立了新的干细胞和再生医学中心。开发细胞替代疗法的项目可能需要研究人员在体外研究灵长类细胞，或者将干细胞植入非人类灵长类动物体内，以测试疗效并评估可能的副作用，然后再进行人体试验。在此背景下，通过威斯康星州国家灵长类研究中心的非人灵长类服务核心提供专业知识、实验室设施和动物。具体服务包括为项目提供适当的猴子和灵长类组织，专门的畜牧业，协助猴子的手术和临床评估等程序，适当的终末程序和组织分析准备，以及提供专门的仪器。 许多出版物依赖于WNPRC的核心干细胞服务。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To test efficacy and assess possible side effects of stem cell based therapies before proceeding to human trials. This service began in July 2007, with the launch of the new UW-Madison Stem Cell & Regenerative Medicine Center. Projects to develop cell replacement therapies may require that researchers study primate cells in vitro or implant stem cells into nonhuman primates to test efficacy and assess possible side effects before proceeding to human trials. In this context, expertise, laboratory facilities and animals are made available through the Nonhuman Primate Services core at the Wisconsin National Primate Research Center. Specific services include the provision of appropriate monkeys and primate tissue for projects, specialized animal husbandry, assistance with procedures such as surgeries and clinical assessments of monkeys, appropriate terminal procedures and preparation of tissues for analysis, and provision of specialized instruments. Numerous publications rely on WNPRC core stem cell services.