STEM CELL & REGENERATIVE MEDICINE CENTER NONHUMAN PRIMATES CORE

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 目的：在进行人体试验之前，测试基于干细胞的疗法的功效并评估可能的副作用。 这项服务于 2007 年 7 月随着新的威斯康辛大学麦迪逊分校干细胞和再生医学中心的成立而开始。开发细胞替代疗法的项目可能需要研究人员在体外研究灵长类动物细胞或将干细胞植入非人类灵长类动物中，以在进行人体试验之前测试疗效并评估可能的副作用。在此背景下，威斯康星国家灵长类动物研究中心的非人类灵长类动物服务核心提供专业知识、实验室设施和动物。具体服务包括为项目提供适当的猴子和灵长类动物组织、专业化畜牧业、协助猴子的手术和临床评估等程序、适当的最终程序和分析用组织的准备，以及提供专门仪器。 许多出版物依赖 WNPRC 核心干细胞服务。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To test efficacy and assess possible side effects of stem cell based therapies before proceeding to human trials. This service began in July 2007, with the launch of the new UW-Madison Stem Cell & Regenerative Medicine Center. Projects to develop cell replacement therapies may require that researchers study primate cells in vitro or implant stem cells into nonhuman primates to test efficacy and assess possible side effects before proceeding to human trials. In this context, expertise, laboratory facilities and animals are made available through the Nonhuman Primate Services core at the Wisconsin National Primate Research Center. Specific services include the provision of appropriate monkeys and primate tissue for projects, specialized animal husbandry, assistance with procedures such as surgeries and clinical assessments of monkeys, appropriate terminal procedures and preparation of tissues for analysis, and provision of specialized instruments. Numerous publications rely on WNPRC core stem cell services.