WEB PORTAL FOR NONHUMAN PRIMATE RESEARCH MODELS

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，不一定是研究者的机构。 描述（由申请人提供）：拟议的项目将建立一个综合性的门户网站，进入有关在生物医学和转化研究中使用非人灵长类动物（NHR）的信息。通过这个“PrimatePortal”链接的信息类型将包括公共资助的资源，这些资源提供对NHP本身的访问，以及在研究背景下对动物进行专门表征的方法和设施。PrimatePortal还将提供描述人类健康和疾病的特定NHP模型的链接，NHP材料的组织和DNA库以及以前研究的书目数据。在项目的第一年，重点将是组织和联系与艾滋病毒/艾滋病研究有关的信息，如无特定病原体的国家卫生方案的可用性、病毒学和免疫学检测资源、专门试剂和其他检测服务，以及这项研究的资助机会。在第二年和第三年，PrimatePortal的范围将扩大到其他研究领域，如其他传染病，生殖和发育（包括干细胞和再生医学），衰老，代谢疾病，神经科学和行为研究。国家灵长类动物研究中心（NPRC）联盟中的工作组目前的活动将被纳入PrimatePortal。拟议的工作建立在信息技术和提供信息服务，以及数据共享和采用最佳实践的倡议，由威斯康星州国家灵长类动物研究中心与其他NPRC和NCRR支持的NHP资源合作，以及通过与临床和转化科学研究所的联系新计划。 公共卫生相关性（由申请人提供）：拟议的项目将通过提高有关非人灵长类动物（NHP）研究使用的信息的可用性，促进基础生物医学和转化研究的过程。通过使用PrimatePortal，研究人员将能够获得关于受益于NHP模型的研究的适当性、可用性和性能的关键信息。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): The proposed project will establish a comprehensive web portal into Information pertaining to the use on nonhuman primates (NHR) in biomedical and translational research. The types of information to be linked through this "PrimatePortal" will include publicly funded resources providing access to the NHP themselves, as well as methods and facilities for specialized characterization of the animals in a research context. PrimatePortal will also provide links describing particular NHP models for human health and disease, tissue and DNA banks for NHP material and bibliographic data on previous research. In the first year of the project the emphasis will be on organizing and linking information pertaining to HIV/AIDS research, such as availability of specific pathogen-free NHP, resources for virological and immunologic testing, specialized reagents and other testing services, and funding opportunities for this research. In the second and third years the scope of PrimatePortal will be expanded to other areas of research, such as other infectious diseases, reproduction and development (including stem cells and regenerative medicine), aging, metabolic diseases, and neurosciences and behavioral research. The current activities of the Working Groups in the consortium of National Primate Research Centers (NPRCs) will be incorporated into PrimatePortal. The proposed work builds on initiatives in information technology and provision of information services, as well as data sharing and adoption of best practices, promoted by the Wisconsin National Primate Research Center in collaboration with other NPRCs and NCRR-supported NHP resources, as well as new programs through linkage with Clinical and Translational Science Institutes. PUBLIC HEALTH RELEVANCE (provided by applicant): The proposed project will facilitate the process of basic biomedical and translational research by enhancing the availability of information regarding the investigational use of nonhuman primates (NHP). Through the use of PrimatePortal, researchers will be able to acquire critical information regarding the appropriateness, availability and performance of studies benefiting from the use of NHP models.