Role of Pollen Oxidase Induced ROS on Allergic Asthma

花粉氧化酶诱导的 ROS 对过敏性哮喘的作用

• 批准号: 8134695
• 负责人: SANJIV SUR
• 金额: $ 21.38万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8134695
• 关键词: 4 hydroxynonenal; A549; Acetaldehyde; Acetylcysteine; Allergens; Allergic; Allergic inflammation; Allergic rhinitis; Ambrosia; Amplifiers; Animals; Antibody Formation; Antigen Presentation; Antigen-Presenting Cells; Antigens; Arabs; Ascorbic Acid; Asthma; B-Lymphocytes; Biochemical; Biological; Biological Models; Bovine Serum Albumin; Breathing; Bronchoalveolar Lavage; Calcium; Cell Culture Techniques; Cell Line; Cells; Chloride Channels; Complex; Cytokine Gene; Data; Dendritic Cells; Dependovirus; Dominant-Negative Mutation; Dose; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Event; Extrinsic asthma; Figs - dietary; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flowers; Generations; Genes; Genetic Materials; Glutathione; Glutathione Disulfide; Human; IL8 gene; IgE; Immune response; Immunoassay; Immunoglobulins; Immunoprecipitation; Inbred BALB C Mice; Inflammation; Inflammatory; Interleukins; Laboratories; Life; Lipid Peroxidation; Lipid Peroxides; Lipids; Liquid substance; Literature; Lung; MAP Kinase Gene; MAPK14 gene; Macrophage Inflammatory Proteins; Major Histocompatibility Complex; Malondialdehyde; Mediating; Memory; Messenger RNA; Mitochondria; Mitogen-Activated Protein Kinases; Modeling; Molecular; Monocyte Chemoattractant Proteins; Mucins; Mucous body substance; Mus; NADP; NADPH Oxidase; Nitroblue Tetrazolium; Ovalbumin; Oxidases; Oxidative Stress; Pathway interactions; Patients; Persons; Phase; Phenotype; Pollen; Production; Property; Protein Isoforms; Proteins; Reaction; Reactive Oxygen Species; Recruitment Activity; Regulation; Research Personnel; Role; SCID Mice; Severe Combined Immunodeficiency; Signal Pathway; Signal Transduction; Specificity; Stress; Superoxides; System; T-Lymphocyte; Testing; Th2 Cells; Tyrosine Phosphorylation; Western Blotting; adaptive immunity; adduct; airway epithelium; airway hyperresponsiveness; airway inflammation; allergic airway inflammation; antigen processing; base; chemokine; cytokine; design; diphenyleneiodonium; enzyme activity; eosinophil; glutathione peroxidase; human subject; mRNA Expression; mitogen-activated protein kinase p38; mouse model; neutralizing antibody; neutrophil; novel; novel therapeutics; overexpression; programs; research study; response; tissue culture; trafficking