Vision In Preschoolers - Hyperopia in Children (VIP-HIP)

学龄前儿童视力 - 儿童远视 (VIP-HIP)

• 批准号: 8486436
• 负责人: ELISE B CINER
• 金额: $ 69.71万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8486436
• 关键词: Amblyopia; Asthenopia; Attention; Behavior; Child; Clinical Practice Guideline; Development; Epidemiologic Studies; Evaluation; Glass; Goals; Guidelines; Headache; Hyperopia; Investigation; Link; Nursery Schools; Ophthalmic examination and evaluation; Outcome Measure; Parents; Performance; Policies; Preschool Child; Randomized Clinical Trials; Reading; Refractive Errors; Schools; Strabismus; Testing; Vision; Vision Screening; Visual Acuity; early childhood; improved; literacy; primary outcome; response

Our prior NEI multicenter Vision In Preschoolers (VIP) studies identified the most effective tests for preschool vision screening, and federal initiatives are currently underway to increase the number of preschool children receiving vision screening and eye examinations. Clinical practice guidelines for children detected with amblyopia or strabismus are clear, but no evidencebased management guidelines are available for managing the many more children detected who have moderate to large hyperopic refractive errors without amblyopia or strabismus. The requirement for accommodation in the uncorrected hyperope may result in eyestrain, headache, intermittent blur and difficulty attending at near, leading to subsequent reading and school performance problems. Several studies have linked hyperopia and reading ability, but largescale investigations have not been conducted in preschool children. Thus, the benefit of detecting children with moderate to large hyperopic refractive errors via vision screening and examining them for prescription of glasses is controversial. The proposed Vision In Preschoolers - Hyperopia In Preschoolers (VIP - HIP) cross- sectional multi-center epidemiological study will answer the following question: Do uncorrected hyperopic (e3D to <6D) 4 or 5yearold children without strabismus or amblyopia perform worse on a battery of educational tests than do comparable emmetropic children? The primary outcome measure will be performance on an assessment of literacy, the Test of Preschool Early Literacy (TOPEL). Results on literacy will be supplemented with results on assessments of attention (LeiterR sustained attention subtest), visualmotor integration (BeeryBuktenica Developmental Test of VisualMotor Integration, 5th Edition [BEERY" VMI]), and behavior and development as provided by parental assessment (Connors Early Childhood [Connors EC] and the Parents' Evaluation of Development Status [PEDS]). The relation between moderate hyperopia and early educational performance will be further investigated by 1) evaluating the association of hyperopia and visual function (visual acuity at distance and near, ocular alignment, stereoacuity), and 2) evaluating accommodative response as a mechanism responsible for any relations found between hyperopia and academic performance. The proposed VIPHIP study will have substantial impact on the understanding of any effects of uncorrected hyperopia on early educational performance and visual function. The results of the study will determine the need for and relevance of a fullscale randomized clinical trial (RCT) to determine whether refractive correction in preschool improves any deficit in performance on early educational tests. The results will also have implications for vision screening policy and prescribing guidelines for glasses.

我们先前在学龄前儿童（VIP）研究中的NEI多中心视野确定了 学龄前视觉筛查和联邦计划的最有效测试是 目前正在进行增加视力的学龄前儿童的数量 筛查和眼睛检查。儿童临床实践指南 用弱视或斜视检测到很明显，但没有证据 管理指南可用于管理更多的孩子 检测到谁在没有中等至大的远视折射率的情况下没有 弱视或斜视。对住宿的要求 未经校正的超管可能会导致眼睛疲劳，头痛，间歇性模糊和 很难参加，导致随后的阅读和学校 性能问题。几项研究已将远视和阅读联系起来 能力，但尚未在学龄前进行大规模调查 孩子们。因此，检测到中度至大型远视儿童的好处 通过视觉筛选并检查它们是否有处方的折射错误 眼镜是有争议的。 学龄前儿童的拟议视觉 - 学龄前儿童（VIP -HIP）横断 部分多中心流行病学研究将回答以下问题：做 未校正的触角（E3D至<6d）4或5岁儿童，没有斜视或 弱视在一系列教育测试中的表现要比可比 雌性儿童？主要结果指标将是在 评估扫盲，学龄前的早期扫盲测试（Topel）。结果 扫盲将补充注意力评估的结果（Leiterr 持续关注子测验），VisualMotor集成（Beerybuktenica发展 VisualMotor集成测试，第五版[Beery“ VMI]），以及行为和行为和 父母评估提供的开发（康纳斯幼儿时期[康纳斯 EC]和父母对发展状况的评估[PED]）。 中等局部和早期教育表现之间的关系将是 通过1）评估远视和视觉功能的关联进一步研究 （在距离和附近的视敏度，眼对准，立体定位）和2）评估 适应性响应，作为负责发现的任何关系的机制 超副局和学业表现。 拟议的胃研究将对对任何的理解产生重大影响 未经矫正的绩效对早期教育表现和视觉功能的影响。 研究结果将确定全尺度的需求和相关性 随机临床试验（RCT），以确定学龄前的屈光度校正 改善早期教育测试表现的任何赤字。结果也将 对视力筛选政策和开处方指南具有影响。