Notre Dame Study of Health & Well-being

圣母大学健康研究

• 批准号: 8531084
• 负责人: Cindy S Bergeman
• 金额: $ 55.04万
• 依托单位: UNIVERSITY OF NOTRE DAME
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-15 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8531084
• 关键词: Accounting; Adult; Affect; Age; Biological; Biology; Caregiver Burden; Chronic; Coupling; Data; Data Set; Development; Disease; Elderly; Emotional; Emotions; Equilibrium; Event; Exposure to; Goals; Growth; Health; Hydrocortisone; Individual; Individual Differences; Investigation; Lead; Life; Life Cycle Stages; Life Stress; Link; Longevity; Measurement; Mental Health; Modeling; Morbidity - disease rate; Neighborhoods; Neurosecretory Systems; Outcome; Pathway interactions; Patient Self-Report; Personal Satisfaction; Personality; Persons; Physiological; Play; Process; Quality of life; Questionnaires; Recovery; Resistance; Resources; Risk; Role; Sampling; Social support; Stress; Surveys; Systems Analysis; Techniques; Testing; Time; Variant; cohort; emotional experience; experience; flexibility; innovation; interest; longitudinal design; middle age; parent project; physical conditioning; psychosocial; resilience; response; scaffold; stress resilience; young adult

DESCRIPTION (provided by applicant): This proposal is for a competitive renewal of the Notre Dame Study of Health and Well-being (NDHWB; R01 AG023571) to support an investigation of the myriad pathways through which life stress contributes to the physical and mental health across the adult lifespan, and of the resilience mechanisms that may protect those individuals from the ill-effects of exposure to adversity. The existing data set is unparalleled in the richness of stress measurement, collected over multiple time points spanning 5 years and including 5 annual questionnaire assessments and three 56-day data bursts (Years 1, 3, & 5; two in the midlife cohort). These data allow us to examine multiple forms of adversity, their common and distinctive linkages, with subsequent indicators of health and well-being. With the present proposal, we broaden the study by collecting additional longitudinal data (expanding the study to 10 years), adding 2 additional data bursts to the later life cohort (Years 7 & 9) and 3 bursts in the mid-life cohort (Years 6, 8, & 10). We extend the study by adding a young adult cohort (ages 18 - 40), assessing them with 5 annual questionnaires and 3 data bursts (years 1, 3, & 5) to better understand how these factors are developed and maintained in adulthood. Finally, we propose to add two 10-day bursts of cortisol assessments (collected 3 X day) on a subset of subjects (50 per cohort) to capture physiological responses to stress. The overarching goal of the expanded project is twofold: to comprehensively and precisely detail the types and qualities of life stress that may initiate the cascade of perceptual, emotional, and biological responses that can lead to disorder and disease, and to examine resilience resources that protect against them.

描述（由申请人提供）：该建议是为了对巴黎圣母夫人的健康和福祉研究（NDHWB； R01 AG023571）进行竞争性更新，以支持对无数途径的调查，这些途径通过这种途径，通过该途径，生命压力会导致成人生活和恢复能力的人的身心健康能够保护那些人的身体健康，并可以保护那些不适的人。现有的数据集无与伦比的压力测量值无与伦比，在多个时间点收集了5年的时间点，其中包括5项年度问卷评估和三个56天的数据爆发（1，3年级，＆5；在中年同龄人群中有两个）。这些数据使我们能够检查多种形式的逆境，即它们的共同和独特的联系，并随后的健康和福祉指标。通过本提案，我们通过收集额外的纵向数据（将研究扩大到10年）来扩大研究，并在后期寿命（7＆9年级）中增加了2次数据爆发，并在中期人生队列中增加了3次爆发（6年，8年级和10年）。我们通过添加一个年轻的成人队列（18-40岁）来扩展研究，并通过5份年度问卷和3次数据爆发（1、3和5年）对其进行评估，以更好地了解这些因素在成年期间如何发展和维持。最后，我们建议在受试者的一部分（每个队列50）上增加两次10天的皮质醇评估（收集3 x天），以捕获对压力的生理反应。扩展项目的总体目标是双重的：全面，精确地详细介绍了生命压力的类型和素质，这些压力的类型和素质可能引发了可能导致混乱和疾病的感知，情感和生物学反应的级联，并检查保护侵害它们的弹性资源。