Visual Science Training Grant

视觉科学培训补助金

• 批准号: 8463203
• 负责人: Z JIMMY ZHOU
• 金额: $ 14.83万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2017-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8463203
• 关键词: Grant; Training; vision science

Program Director/Principal Investigator (Last, First, Middle): Zhou, Z. Jimmy Abstract This application proposes to provide integrative training in visual science research at Yale University School of Medicine, with a special emphasis on visual neuroscience. The goal of this program is to foster interdisciplinary approaches to visual neuroscience that will interface with molecular genetics and clinical medicine with respect to development, organization, function and dysfunction of the eye and the central visual system. Twelve faculty preceptors from five basic and clinical departments participate in this multidisciplinary program. These faculty members lead vibrant vision research programs in a vision research community at Yale that has undergone an exciting phase of revitalization and expansion, and that has attracted an increasing number of outstanding graduate students and postdoctoral fellows. The proposed training program offers both depth and breadth. The depth derives from its substantive focus on the neurobiology of the eye and the visual system. The breadth of the program derives from the diversity of approaches, spanning molecular, developmental, systems, cognitive and theoretical neuroscience, as well as from the range of experimental models used in these studies, spanning zebrafish, rodents, and primates. Faculty interests range from retinal development and degeneration, retinal physiology and circuits to visual cortical function and visual behavior. Methodologies include cloning; cell culture; immunocytochemistry; in situ hybridization; gene transfection and transgenic technology, electron and two photon microscopy; patch-clamp and multielectrode recording; electroretinograph, calcium and other forms of optical imaging; biochemistry and molecular analyses; psycho- pharmacology; rodent, monkey and human behavior; in vivo extracellular recording in behaving animals; and fMRI and PET imaging in human subjects. Two predoctoral and two postdoctoral positions are requested. Trainees will be selected from a variety of backgrounds in biological sciences on the basis of their potential for excellence and leadership in research by an Executive Committee. Mentors are Ph.D.s and M.D.s. with NEI and other NIH institute grants or NEI related research foci. Training includes coursework, intensive research apprentice-ship, structured seminar programs, laboratory and departmental presentations of research progress, and instructions on responsible research conduct. PHS 398/2590 (Rev. 06/09) Page Continuation Format Page

项目主任/首席调查员(最后、第一、中间)：周，Z.吉米 摘要 这项申请建议在耶鲁大学提供视觉科学研究的综合培训 医学院，特别强调视觉神经科学。这项计划的目标是促进 将与分子遗传学和临床相结合的视觉神经科学的跨学科方法 与眼和中央视觉的发育、组织、功能和功能障碍有关的医学 系统。来自5个基础和临床科室的12名教员参加了这一多学科的活动。 程序。这些教员在视觉研究社区领导着充满活力的视觉研究项目，网址为 耶鲁大学经历了令人兴奋的振兴和扩张阶段，这吸引了 优秀研究生和博士后人数不断增加。拟议的培训计划 既有深度又有广度。深度源于它对眼睛神经生物学的实质性关注和 视觉系统。该计划的广度来自于方法的多样性，跨越分子， 发展、系统、认知和理论神经科学，以及从实验范围 这些研究中使用的模型包括斑马鱼、啮齿动物和灵长类动物。教职员工的兴趣范围从视网膜 发育和退化、视网膜生理和回路对视觉皮质功能和视觉行为的影响。 方法包括克隆；细胞培养；免疫细胞化学；原位杂交；基因转染和 转基因技术；电子和双光子显微镜；膜片钳和多电极记录； 视网膜电图仪，钙和其他形式的光学成像；生物化学和分子分析；心理分析 药理学；啮齿动物、猴子和人类行为；动物行为的活体细胞外记录；以及 人体功能磁共振成像和正电子发射计算机断层扫描。 申请两个博士后和两个博士后职位。受训者将从各种不同的 生物科学的背景，基于他们在研究方面的卓越潜力和领先地位 一个执行委员会。导师是博士和医学博士。与NEI和其他NIH研究所拨款或NEI相关 研究重点。培训包括课程作业，密集的研究学徒，有组织的研讨会计划， 实验室和部门对研究进展的介绍，以及关于负责任研究的指示 品行。 PHS 398/2590(06/09版)页面续格式页面