CRN4: Cancer Research Resources & Collaboration in Integrated Health Care Systems

CRN4：癌症研究资源

• 批准号: 8550798
• 负责人: LAWRENCE H KUSHI
• 金额: $ 303.24万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-25 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8550798
• 关键词: Administrator; Area; Cancer Center; Cancer Research Network; Caring; Clinical; Clinical Data; Collaborations; Communication; Comprehensive Health Care; Data; Databases; Decision Making; Development; Electronic Health Record; Epidemiologist; Epidemiology; Evolution; Funding; Government Agencies; Health; Health Insurance Portability and Accountability Act; Health Maintenance Organizations; Health Planning; Health Services; Health Services Research; Healthcare; Healthcare Systems; Individual; Informatics; Information Systems; Infrastructure Activities; Institution; Integrated Delivery Systems; Integrated Delivery of Health Care; Integrated Health Care Systems; Investigator-Initiated Research; Knowledge; Learning; Malignant Neoplasms; Mentors; Molecular; National Cancer Institute; Nature; Pilot Projects; Population; Population Sciences; Positioning Attribute; Prevention; Public Domains; Public Health; Research; Research Infrastructure; Research Personnel; Research Support; Resource Development; Resources; Scientist; Source; Structure; System; Training Programs; Translating; Translational Research; Treatment outcome; Trust; Work; anticancer research; cancer care; cancer prevention; career development; cost; data modeling; distributed data; health care quality; health care service organization; improved; medical schools; member; operation; outreach; programs; research study; screening; tool; virtual

DESCRIPTION (provided by applicant): This application is for a competitive renewal and transformation of the HMO Cancer Research Network (CRN) into a research resource. The CRN, which has been continuously funded since 1999, provides infrastructure support to conduct cancer research in the setting of not-for-profit integrated health care delivery systems. The setting has advantages for conducting population sciences research that collectively result in a unique, unparalleled resource for conducting epidemiologic and health services research in cancer. These advantages include externally-funded research groups with investigators with expertise in conducting public-domain cancer research in these settings; defined populations with a combined membership of over 10 million individuals for whom health care is provided; clinical and administrative data systems that capture most aspects of care; development and implementation of common data models in the Virtual Data Warehouse (VDW) to facilitate collaborative and multi-institutional research; and access to clinicians and administrators to facilitate translation of research findings to practice. We plan to enhance the CRN in several areas, including: Establishing an Informatics Core focused on continual improvement of the VDW through implementation of distributed query tools to facilitate preparatory-to-research and collaborative research studies, and improvement of existing and implementation of new VDW domains of relevance to cancer research; identification and promotion of research in strategic areas for which the CRN is uniquely positioned (i.e., Prevention & Screening; Treatment & Outcomes; Biospecimens & Molecular Applications; Communications & Decision-Making; Health Care Quality & Cost; and Dissemination & Implementation); institutionalizing a CRN Scholars mentored career development program for junior investigators; continuation of a Developmental and Pilot Studies Program to support pilot studies and to enhance infrastructure; and implementation of an Outreach and External Collaborations Core to facilitate research collaborations. This continued infrastructure support will enable and facilitate researchers' continued access to large integrated delivery systems and motivate continued evolution as the nation's premier learning healthcare systems.

描述（由申请人提供）：本申请旨在将 HMO 癌症研究网络 (CRN) 竞争性更新并转变为研究资源。 CRN 自 1999 年以来一直得到持续资助，为在非营利性综合医疗保健服务系统中开展癌症研究提供基础设施支持。该环境具有开展人口科学研究的优势，这些优势共同为开展癌症流行病学和卫生服务研究提供了独特、无与伦比的资源。这些优势包括外部资助的研究小组，其研究人员具有在这些环境中进行公共领域癌症研究的专业知识；为其提供医疗保健的总人数超过 1000 万的特定人群；捕获护理大部分方面的临床和管理数据系统；在虚拟数据仓库（VDW）中开发和实施通用数据模型，以促进协作和多机构研究；以及与临床医生和管理人员的联系，以促进研究成果转化为实践。我们计划在几个领域加强 CRN，包括： 建立一个信息学核心，重点关注通过实施分布式查询工具不断改进 VDW，以促进研究准备和协作研究，以及改进现有的和实施与癌症研究相关的新 VDW 领域；确定和促进 CRN 独特定位的战略领域的研究（即预防和筛查；治疗和结果；生物样本和分子应用；沟通和决策；医疗保健质量和成本；以及传播和实施）；将 CRN 学者指导的初级研究者职业发展计划制度化；继续开展发展和试点研究计划，以支持试点研究并加强基础设施；实施外展和外部合作核心以促进研究合作。这种持续的基础设施支持将使研究人员能够继续访问大型集成交付系统，并促进其作为国家首要学习医疗保健系统的持续发展。