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Noninvasive Evaluation of Pediatric CNS Tumors

Noninvasive Evaluation of Pediatric CNS Tumors
儿童中枢神经系统肿瘤的无创评估
批准号：
8763439
负责人：
Katherine e Warren
金额：
$10.27万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8763439
关键词：
AdultAngiogenesis InhibitionAngiogenesis InhibitorsAntineoplastic AgentsBiologicalBiopsyBrain NeoplasmsCentral Nervous System NeoplasmsChildChildhood Central Nervous System NeoplasmCytostaticsDiagnostic radiologic examinationDiffusionDiffusion Magnetic Resonance ImagingDiscipline of Nuclear MedicineDiseaseDoseEdemaEvaluationFailureFlareGadoliniumGoalsGoldImageLaboratoriesLife ExpectancyMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaximum Tolerated DoseMeasurementMeasuresModalityNew AgentsOutcomePatientsPerfusionPhase I Clinical TrialsPhase II Clinical TrialsPhysiologyPositron-Emission TomographyPrognostic FactorProgression-Free SurvivalsResearchSpectrum AnalysisSurrogate MarkersTimeToxic effectVascular Endothelial Growth FactorsVascular PermeabilitiesWorkantitumor agentbevacizumabdrug efficacyexperiencegadolinium oxideimaging modalityneuro-oncologyresponsesuccesstumortumor progressiontwo-dimensional

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中文摘要
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英文摘要
There are several sections of this project involving different aspects of imaging. 1. MR sequences: We are currently working in the Laboratory of Diagnostic Radiology Research evaluating multiple MR sequences on children with brain tumors, longitudinally, to assess outcome to tehrapy and prognostic factors. These imaging modalities include spectroscopy (single voxel, CSI and multislice multivoxel), perfusion studies (DEMRI, DSC-MRI) and diffusion tenor imaging. 2. Results from NMRS are being compared to the "gold standard" in adult neuro-oncology, i.e. FDG-PET, to determine the correlation between results of each modality.
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Establishment of an International DIPG Registry
  • 批准号：
    8763499
  • 项目类别：
  • 资助金额：
    $5.14万
  • 财政年份：
    --
  • 负责人：
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  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
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  • 批准号：
    8763182
  • 项目类别：
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    $10.27万
  • 财政年份：
    --
  • 负责人：
    Katherine e Warren
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
Imaging as a Biomarker for Diffuse Intrinsic Brainstem Gliomas
  • 批准号：
    8763142
  • 项目类别：
  • 资助金额：
    $1.03万
  • 财政年份：
    --
  • 负责人：
    Katherine e Warren
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
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  • 批准号：
    7292865
  • 项目类别：
  • 资助金额：
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  • 财政年份：
    --
  • 负责人：
    Katherine e Warren
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
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