Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)"

到2030年，美国总人口中约有五分之一将超过65岁。 阿尔茨海默病和相关痴呆（ADRD）以及多种合并症需要新的循证医学证据。 临床护理策略。他们有能力将自己的医学知识与流行病学工具联合收割机结合起来， 在基础科学和社会科学中，医生科学家在确定床边问题方面发挥着关键作用 并开发新的方法来预防，诊断，治疗和管理ADRD。尽管有独特的技能 和医生科学家的观点，这种受训人员的管道一直在下降。这表示 在准备为ADRD研究做出贡献的医生-科学家的发展方面存在重大差距。的使命 杜克大学为下一代创造ADRD研究人员-刺激获得研究 住院医师（CARiNG-StARR）计划是培养生物医学研究的医生科学家， 研究人员将领导新的翻译和临床研究的开发、实施和评估。 治疗ADRD的方法。CARiNG-StARR将培训三个临床学科的住院研究者： 家庭医学、精神病学和神经病学，重点关注三个领域：1）新的联系和预防 策略2）合并症和护理模式，以及3）ADRD相关的健康差异。该方案将包括 四个培训组成部分：1）综合教学法，涵盖基础，转化和临床研究， 专业发展，重点放在ADRD的研究上; 2）开发和完成一个 ADRD研究项目和个性化的职业发展计划; 3） 在ADRD领域的学术活动;和4）在家庭医学，精神病学，或 神经病学，并继续临床和研究培训的子专业或奖学金。CARiNG-StARR 将由MPIs Anthony Viera，MD，MPH（家庭医学）和石楠的执行委员会（EC）领导 惠特森，医学博士，MHS（杜克老龄化和人类发展研究中心），和一个CARiNG-StARR 副项目主任从医生科学家发展办公室，沿着与扩大EC的 派驻计划主管和计划协调员，利用强大的资源和 团队42多学科，资金充足，经验丰富的教师导师/导师工作在 ADRD和相关领域。此应用程序要求每年支持三名住院研究员， 每名受训人员在实习期间都得到12个月的研究支助。完成后， 这些人将准备在一个研究密集的奖学金，竞争校外进一步培训 资助，并成为下一代的医生，科学家领导和指导实习生在临床- 以ADRD为重点的研究。实现该方案的目标将满足以下迫切需要：1） 在全国各地的医学院中增加更多的全职学术医生-科学家和导师; 2） 创新和新策略的临床转化，以改善ADRD患者的健康和护理。

In 2030, roughly a fifth of the total population in the US will be over age 65.The rising number of seniors with Alzheimer’s disease and related dementias (ADRDs) and multiple comorbidities requires new evidence-based clinical care strategies. With their ability to combine their medical knowledge with the tools of epidemiology, basic science, and social science, physician-scientists play a critical role in identifying questions at the bedside and developing novel approaches to prevent, diagnose, treat, and manage ADRD. Despite the unique skills and perspectives of physician-scientists, the pipeline of such trainees has been in decline. This represents a major gap in the development of physician-scientists prepared to contribute to ADRD research. The mission of the Duke University Creating ADRD Researchers for the Next Generation-Stimulating Access to Research in Residency (CARiNG-StARR) Program is to train physician-scientists in biomedical research to cultivate investigators who will lead the development, implementation, and evaluation of new translational and clinical modalities to address ADRD. CARiNG-StARR will train resident-investigators across three clinical disciplines: Family Medicine, Psychiatry, and Neurology focusing on three areas: 1) novel links and prevention strategies 2) comorbidities and care models, and 3) ADRD-related health disparities. The program will consist of four training components: 1) comprehensive didactics covering basic, translational, and clinical research and professional development with emphasis placed on research in ADRD; 2) development and completion of an ADRD research project and an individualized career development plan; 3) a record of accomplishment of scholarly activity in the field of ADRD; and 4) eligibility for board certification in Family Medicine, Psychiatry, or Neurology, and continuation of clinical and research training in a sub-specialty or fellowship. CARiNG-StARR will be led by an Executive Committee (EC) of MPIs Anthony Viera, MD, MPH (Family Medicine) and Heather Whitson, MD, MHS (Duke Center for the Study of Aging and Human Development), and a CARiNG-StARR Associate Program Director from the Office of Physician-Scientist Development, along with an Expanded EC of Residency Program Directors and a Program Coordinator, capitalizing on a robust array of resources and a team of 42 multi-disciplinary, well-funded, and experienced faculty preceptors/mentors working in ADRD and relevant fields. This application requests support for three resident-Investigators each year with each trainee supported for 12-months of research during the duration of their residency. Upon completion, these individuals will be prepared for further training in a research-intense fellowship, competing for extramural funding, and becoming the next generation of physician-scientists leading and mentoring trainees in clinically- oriented research focusing on ADRD. Achievement of the program's objectives will fulfill urgent needs for: 1) more full-time academic physician-scientists and mentors in medical schools throughout the country and 2) innovations and clinical translation of novel strategies to improve the health and care of people with ADRD.