Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)"

到2030年，美国总人口的大约五分之一将超过65岁。 阿尔茨海默病和相关痴呆(ADRD)和多发性共病需要新的循证证据 临床护理策略。凭借他们将医学知识与流行病学工具相结合的能力， 基础科学和社会科学，内科科学家在确定床边的问题方面发挥着关键作用 以及开发预防、诊断、治疗和管理ADRD的新方法。尽管有独一无二的技能 以及内科科学家的观点，这类受训人员的数量一直在下降。这表示一个 准备为ADRD研究做出贡献的内科科学家的发展存在重大差距。的使命 杜克大学为下一代培养ADRD研究人员--在 住院医师(CARE-STAR)计划是培养生物医学研究方面的内科科学家 将领导新的翻译和临床研究的开发、实施和评估的研究人员 应对ADRD的方式。CARE-STAR将培训三个临床学科的常驻研究员： 家庭医学、精神病学和神经学集中在三个领域：1)新的联系和预防 战略2)合并症和护理模式，以及3)与ADRD相关的健康差距。该计划将包括 四个培训组成部分：1)全面的教学，涵盖基础、翻译和临床研究 专业发展，重点是ADRD方面的研究；2)开发和完成 ADRD研究项目和个性化的职业发展计划；3)成就记录 在ADRD领域的学术活动；以及4)获得家庭医学、精神病学或 神经学，以及在专科或研究员中继续临床和研究培训。关爱--明星 将由医学硕士Anthony Viera、公共卫生硕士(家庭医学)和Heather组成的执行委员会(EC)领导 惠特森，医学博士，MHS(杜克大学老龄化和人类发展研究中心)，关怀明星 来自医生-科学家发展办公室的副项目主任，以及扩展的EC 派驻计划主任和计划协调员，利用一系列强大的资源和 由42名多学科、资金充足且经验丰富的教师组成的团队在 ADRD及相关字段。此应用程序每年请求为三名驻地调查员提供支持 每个受训者在他们的住院期间支持为期12个月的研究。完成后， 这些人将准备在研究密集的奖学金中接受进一步培训，竞争校外奖学金。 资助，并成为下一代领导和指导临床实习生的内科科学家- 以ADRD为重点的研究。方案目标的实现将满足以下方面的迫切需求：1) 更多全职学术内科医生-科学家和全国各地医学院的导师和2) 创新和临床翻译新的战略，以改善ADRD患者的健康和护理。

In 2030, roughly a fifth of the total population in the US will be over age 65.The rising number of seniors with Alzheimer’s disease and related dementias (ADRDs) and multiple comorbidities requires new evidence-based clinical care strategies. With their ability to combine their medical knowledge with the tools of epidemiology, basic science, and social science, physician-scientists play a critical role in identifying questions at the bedside and developing novel approaches to prevent, diagnose, treat, and manage ADRD. Despite the unique skills and perspectives of physician-scientists, the pipeline of such trainees has been in decline. This represents a major gap in the development of physician-scientists prepared to contribute to ADRD research. The mission of the Duke University Creating ADRD Researchers for the Next Generation-Stimulating Access to Research in Residency (CARiNG-StARR) Program is to train physician-scientists in biomedical research to cultivate investigators who will lead the development, implementation, and evaluation of new translational and clinical modalities to address ADRD. CARiNG-StARR will train resident-investigators across three clinical disciplines: Family Medicine, Psychiatry, and Neurology focusing on three areas: 1) novel links and prevention strategies 2) comorbidities and care models, and 3) ADRD-related health disparities. The program will consist of four training components: 1) comprehensive didactics covering basic, translational, and clinical research and professional development with emphasis placed on research in ADRD; 2) development and completion of an ADRD research project and an individualized career development plan; 3) a record of accomplishment of scholarly activity in the field of ADRD; and 4) eligibility for board certification in Family Medicine, Psychiatry, or Neurology, and continuation of clinical and research training in a sub-specialty or fellowship. CARiNG-StARR will be led by an Executive Committee (EC) of MPIs Anthony Viera, MD, MPH (Family Medicine) and Heather Whitson, MD, MHS (Duke Center for the Study of Aging and Human Development), and a CARiNG-StARR Associate Program Director from the Office of Physician-Scientist Development, along with an Expanded EC of Residency Program Directors and a Program Coordinator, capitalizing on a robust array of resources and a team of 42 multi-disciplinary, well-funded, and experienced faculty preceptors/mentors working in ADRD and relevant fields. This application requests support for three resident-Investigators each year with each trainee supported for 12-months of research during the duration of their residency. Upon completion, these individuals will be prepared for further training in a research-intense fellowship, competing for extramural funding, and becoming the next generation of physician-scientists leading and mentoring trainees in clinically- oriented research focusing on ADRD. Achievement of the program's objectives will fulfill urgent needs for: 1) more full-time academic physician-scientists and mentors in medical schools throughout the country and 2) innovations and clinical translation of novel strategies to improve the health and care of people with ADRD.