Macromolecular Crystallography

高分子晶体学

• 批准号: 8377150
• 负责人: ALAN M FRIEDMAN
• 金额: $ 7.9万
• 依托单位: PURDUE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8377150
• 关键词: Address; Administrator; Award; Biological Process; Cancer Center Support Grant; Chemicals; Computer Systems; Crystallization; Crystallography; Data; Diagnosis; Electronics; Ensure; Equipment; Funding; Individual; Left; Malignant Neoplasms; Measures; Minor; Molecular Structure; NCI Center for Cancer Research; Pain; Peer Review; Prevention; Process; Reporting; Research; Research Personnel; Resource Sharing; Role; Services; Source; United States National Institutes of Health; Universities; Wages; X-Ray Crystallography; computer network; cost; instrumentation; macromolecule; member; novel strategies; operation; programs; repaired; structural biology

The analysis of macromolecular structures by X ray crystallography provides data critical for understanding the beneficial and adverse functions of biological macromolecules and assemblies associated with cancer, which is a research focus of the Purdue University Center for Cancer Research's Chemical and Structural Biology Scientific Program. The Macromolecular Crystallography Shared Resource was established in 1998 and promotes cancer-related crystallographic research by ensuring the continuous availability of advanced facilities for crystallization and x-ray diffraction as well as the technical guidance necessary for their optimal use. The Macromolecular Crystallography Shared Resource provides essential services to the Chemical and Structural Biology Scientific Program in the Purdue University Center for Cancer Research and provides local, continuously available support to the internationally acclaimed research by Center for Cancer research crystallographers.

X射线结晶学对大分子结构的分析为理解 与癌症相关的生物大分子和组装体的有益和不利功能， 这是普渡大学癌症研究中心化学和结构研究的研究重点 生物科学计划。1998年建立了大分子结晶学共享资源 并通过确保持续提供先进的 结晶和x射线衍射设备以及使其达到最佳状态所需的技术指导 使用。大分子结晶学共享资源为化工和化工企业提供必要的服务 普渡大学癌症研究中心的结构生物学科学计划并提供 为癌症研究中心在国际上享有盛誉的研究提供本地、持续的支持 结晶学家。