A Stage I Study of Computer Based Training in CBT for Alcohol Use Disorders

基于计算机的酒精使用障碍 CBT 培训的第一阶段研究

基本信息

  • 批准号:
    8353004
  • 负责人:
  • 金额:
    $ 16.85万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2012
  • 资助国家:
    美国
  • 起止时间:
    2012-07-05 至 2014-06-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Computer-assisted treatments have tremendous potential for making evidence based therapies more widely available to those who may benefit from them, standardizing treatment delivery, extending and freeing up the time of busy clinicians, and reducing the costs of treatment. Despite their enormous promise, however, well- controlled randomized clinical trials of computer-assisted therapies remain rare, and there are fewer still that would meet established methodological standards for the evaluation of clinician-delivered behavioral therapies. We have developed a computer-assisted version of CBT (CBT4CBT) and have demonstrated its efficacy, durability, and specificity as an adjunct to outpatient treatment for illicit drug dependence. In 2009, we were approached by NIAAA to develop a web-based version of CBT4CBT specifically for individuals with alcohol use disorders, as there are no existing full-scale computer-assisted CBT programs for alcohol use disorders with demonstrated efficacy. Funded through ARRA, development of the web based CBT4CBT alcohol program was completed in 2011, within our specified timeline. We now propose an exploratory, Stage I study to evaluate the program's feasibility and preliminary efficacy with treatment-seeking alcohol dependent individuals. We propose to conduct an 8-week randomized clinical trial with 90 treatment-seeking individuals meeting current criteria for alcoho dependence. Participants will be randomized to one of three conditions: (1) standard outpatient counseling, (2) counseling plus CBT4CBT (the website delivered as an add-on to standard counseling, or (3) web-based CBT4CBT as a virtual standalone (CBT4CBT plus minimal clinical monitoring). This design is novel for a Stage 1 study in that it will allow evaluation of the program in two of the forms in which it is most likely to be implemented clinically (add-on and stand alone). The primary outcome measures will be reduction in alcohol use (percent days abstinent, heavy drinking days by week). Measures of treatment utilization and other secondary outcomes will be used to evaluate whether web-based CBT4CBT retains key characteristics of traditional clinician-delivered CBT (e.g., acquisition of coping skills, use of change strategies). PUBLIC HEALTH RELEVANCE: This project proposes to conduct an exploratory, Stage 1 study to evaluate the feasibility and preliminary efficacy of a web-based version of Cognitive Behavioral Therapy (CBT4CBT) adapted for use by individuals with alcohol use disorders. The availability of an effective computer-assisted treatment for alcohol dependence could greatly broaden the availability of treatment and hence have a major impact on public health through making treatment more available to underserved populations.
描述(由申请人提供):计算机辅助治疗具有巨大的潜力,可以使基于证据的治疗更广泛地提供给那些可能从中受益的人,标准化治疗交付,延长和解放忙碌的临床医生的时间,并降低治疗成本。然而,尽管计算机辅助疗法有着巨大的前景,但控制良好的随机临床试验仍然很少,而且更少的是能够满足临床医生提供的行为疗法评估的既定方法标准。我们开发了一种计算机辅助CBT (CBT4CBT),并证明了其作为非法药物依赖门诊辅助治疗的有效性、持久性和特异性。2009年,NIAAA与我们接洽,专门为酒精使用障碍患者开发一种基于网络的CBT4CBT版本,因为目前还没有针对酒精使用障碍的全面计算机辅助CBT项目被证明有效。在ARRA的资助下,基于网络的CBT4CBT酒精项目的开发于2011年在我们指定的时间内完成。我们现在提出一项探索性的第一阶段研究,以评估该计划对寻求治疗的酒精依赖个体的可行性和初步疗效。我们建议对90名符合当前酒精依赖标准的寻求治疗的个体进行为期8周的随机临床试验。参与者将被随机分配到以下三种情况之一:(1)标准门诊咨询,(2)咨询加CBT4CBT(网站作为标准咨询的附加内容提供),或(3)基于网络的CBT4CBT作为虚拟独立(CBT4CBT加最小临床监测)。这种设计对于第一阶段的研究来说是新颖的,因为它允许以两种最有可能在临床实施的形式(附加和独立)对项目进行评估。主要结果测量将是减少酒精使用(戒酒天数百分比,每周酗酒天数百分比)。治疗利用和其他次要结果的测量将用于评估基于网络的CBT4CBT是否保留了传统临床提供的CBT的关键特征(例如,获得应对技能,使用改变策略)。

项目成果

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KATHLEEN M. CARROLL其他文献

KATHLEEN M. CARROLL的其他文献

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{{ truncateString('KATHLEEN M. CARROLL', 18)}}的其他基金

Identification of a Meaningful Cocaine Use Outcome Measure
确定有意义的可卡因使用结果衡量标准
  • 批准号:
    9750045
  • 财政年份:
    2016
  • 资助金额:
    $ 16.85万
  • 项目类别:
Research Core Psychotherapy Devleopment Research Center
研究核心 心理治疗发展研究中心
  • 批准号:
    8742765
  • 财政年份:
    2014
  • 资助金额:
    $ 16.85万
  • 项目类别:
Administrative Core Psychotherapy Development Research Center
行政核心心理治疗发展研究中心
  • 批准号:
    8742764
  • 财政年份:
    2014
  • 资助金额:
    $ 16.85万
  • 项目类别:
Project#1: Cognitive Control Training to Enhance CBT4CBT
项目
  • 批准号:
    8742766
  • 财政年份:
    2014
  • 资助金额:
    $ 16.85万
  • 项目类别:
Neural mechanisms of CBT in cocaine dependence
可卡因依赖中 CBT 的神经机制
  • 批准号:
    8914560
  • 财政年份:
    2013
  • 资助金额:
    $ 16.85万
  • 项目类别:
Neural mechanisms of CBT in cocaine dependence (Gender Differences Supplement)
可卡因依赖中 CBT 的神经机制(性别差异补充)
  • 批准号:
    8803086
  • 财政年份:
    2013
  • 资助金额:
    $ 16.85万
  • 项目类别:
Neural mechanisms of CBT in cocaine dependence
可卡因依赖中 CBT 的神经机制
  • 批准号:
    8731378
  • 财政年份:
    2013
  • 资助金额:
    $ 16.85万
  • 项目类别:
Neural mechanisms of CBT in cocaine dependence
可卡因依赖中 CBT 的神经机制
  • 批准号:
    8708818
  • 财政年份:
    2013
  • 资助金额:
    $ 16.85万
  • 项目类别:
Neural mechanisms of CBT in cocaine dependence
可卡因依赖中 CBT 的神经机制
  • 批准号:
    8534513
  • 财政年份:
    2013
  • 资助金额:
    $ 16.85万
  • 项目类别:
Computer Based Training in CBT for Spanish-Speaking Substance Users
为西班牙语药物使用者提供基于计算机的 CBT 培训
  • 批准号:
    9231403
  • 财政年份:
    2012
  • 资助金额:
    $ 16.85万
  • 项目类别:

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