Short-Term Training to Increase the Diversity Pipeline in Heart/Lung/Blood Resear

短期培训以增加心/肺/血液研究的多样性管道

• 批准号: 8475502
• 负责人: MARLYS Hearst WITTE
• 金额: $ 23.69万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8475502
• 关键词: Area; Arizona; Attitude; Basic Science; Biocompatible Materials; Bioinformatics; Biology; Biomedical Engineering; Biomedical Research; Blood; Brain; Cardiovascular system; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Communication; Communities; Complex; Computer Simulation; Curiosities; Databases; Development; Development Plans; Disadvantaged; Educational Curriculum; Educational workshop; Effectiveness; Equilibrium; Esapent; Evaluation; Faculty; Fostering; Future; Genomics; Goals; Health; Health Professional; Heart; Heart Diseases; Hematological Disease; Hematopoietic Neoplasms; Hypertrophy; Image; In Situ; In Vitro; Individual; Institutes; Institution; Interdisciplinary Study; International; Knowledge; Laboratories; Leadership; Link; Lung; Malignant Neoplasms; Medical; Medical Research; Medical Students; Medicine; Mentors; Modeling; Molecular Medicine; Monitor; Multimedia; Nature; Neurosciences; Participant; Physicians; Physiology; Population; Productivity; Prosthesis; Proteomics; Ramp; Reaction; Recruitment Activity; Registries; Research; Research Infrastructure; Research Methodology; Research Personnel; Science; Scientist; Specialized Center; Students; Thinking; Time; Training; Training Programs; Translating; Translation Process; Translations; Underrepresented Minority; United States National Institutes of Health; Universities; Visit; base; bench to bedside; career; college; design; experience; high school; in vivo; innovation; interest; lymphology; peer; professor; programs; role model; skills; undergraduate student; virtual

The University of Arizona (UA) College of Medicine Diverse Student Medical Research Program (DSMRP) will introduce, train, and nurture inquiring medical and undergraduate students [including under-represented minorities (URM)] in health-related basic/clinical biomedical research (emphasizing cardiovascular, pulmonary, blood); and encourage subsequent intensive/extensive research experiences to retain and strengthen the diverse student researcher pipeline. We will build on the infrastructure, high level of student and faculty mentor participation, esprit-de-corps, and outstanding trainee productivity of our current medical student and disad- vantaged high school student programs to bridge the discontinuous diversity pipeline of entering and exiting students as they advance in training and strive for professional/academic careers. Full-time summer-vacation laboratory/clinical investigations will be integrated into an innovative Curriculum on Medical Ignorance (CMI) concentrated in a Summer Institute (SIMI) and sustained through year-round trainee-related enrichment activities. These include topical workshops, clinical correlations, advanced extracurricular research in a Research Honors Distinction Track, Introduction to Molecular Medicine laboratory practicum, a new progres- sive "Translating Translation" face-to-face/online curriculum interweaving the known and unknown from bench to bedside to community, research methodology/communications/leadership/responsible conduct seminars, visiting professors, and career advising. CMI fosters attitudes and questioning skills to recognize and deal with the vast shifting world of medical ignorance ["what we know we don't know (research), don't know we don't know(discovery), and think we know but don't (error)"]. A unique Virtual Clinical Research Center with Questionarium forms a centerpiece for training and national/international networking. Organized around expanding UA Specialized Centers of Excellence and departments and overseen by Program Director, Basic- Clinical Science Advisors, and faculty-elected Medical Student Research Committee, research encompasses cross-cutting themes and in vivo, in vitro, in situ, in silico, and modeling approaches to the cardiovascular (CV) system and its disorders (cardiac contractility, hypertrophy, development; genomics/proteomics, imaging, biomaterials, prosthetics; endothelial biology, microcirculatory physiology, lymphology, bioengineering); and interdigitating research in cancer, neurosciences, bioinformatics, and other topics of interest to students. Based on our ~30-year track record and access to diverse/disadvantaged populations reflected in 729 medical students and 474 high school students trained to date, we anticipate that DSMRP will cultivate many diverse scientific physician contributors to the research enterprise and a growing cadre of medical scientist leaders to energize the scanty diversity pipeline of healthcare professionals and translational researchers. Detailed S/T and L/T formative/summative program and participant evaluation including database registry, individual development plans, and career portfolios, will document effectiveness and promote networking.

亚利桑那大学（UA）医学院多样化学生医学研究计划（DSMRP）将 介绍、培训和培养有探究精神的医学生和本科生[包括代表性不足的学生 少数民族（URM）]在与健康有关的基础/临床生物医学研究（重点是心血管，肺， 血液）;并鼓励随后的深入/广泛的研究经验，以保持和加强 多样化的学生研究人员管道。我们将建立在基础设施，高水平的学生和教师导师 参与，团队精神，和我们目前的医学生和disad优秀的实习生生产力- 先进的高中学生计划，以弥合进入和退出的不连续的多样性管道 学生，因为他们在培训和争取专业/学术生涯的进步。全日制暑假 实验室/临床研究将被整合到一个创新的课程医学无知（CMI） 集中在一个夏季研究所（SIMI），并通过全年与受训者相关的充实来维持 活动这些包括专题研讨会，临床相关性，高级课外研究， 科研荣誉优异奖，分子医学实验室实习介绍，新进展- sive“翻译翻译”面对面/在线课程交织已知和未知的板凳 床边社区，研究方法/通信/领导/负责任的行为研讨会， 客座教授和职业顾问CMI培养态度和提问技巧，以识别和处理 医学无知的巨大变化世界[“我们知道我们不知道（研究），不知道我们不知道 我们知道（发现），以为我们知道但不知道（错误）。独特的虚拟临床研究中心， 博物馆是培训和国家/国际网络的中心。围绕着 扩大UA专业卓越中心和部门，并由项目总监监督，基础- 临床科学顾问和学院选出的医学生研究委员会，研究包括 心血管（CV）的交叉主题和体内、体外、原位、计算机模拟和建模方法 系统及其疾病（心肌收缩力，肥大，发育;基因组学/蛋白质组学，成像， 生物材料、修复术;内皮生物学、微循环生理学、淋巴学、生物工程）;以及 在癌症，神经科学，生物信息学和学生感兴趣的其他主题的交叉研究。 基于我们约30年的跟踪记录和729项医疗报告中反映的对不同/弱势群体的接触， 学生和474名高中学生接受了培训，我们预计，DSMRP将培养许多不同的 科学医生对研究事业的贡献和越来越多的医学科学家领导干部， 激励医疗保健专业人员和翻译研究人员的稀缺多样性管道。详细S/T 和L/T形成性/总结性计划和参与者评估，包括数据库登记，个人 发展计划和职业组合将记录成效并促进网络联系。