Capacity Building for Lifespan Focused Substance Use Disorder Research in Ukraine

乌克兰以寿命为中心的药物使用障碍研究能力建设

• 批准号: 8507820
• 负责人: ROBERT ALPERT ZUCKER
• 金额: $ 21.79万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-09 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8507820
• 关键词: 21 year old; Academy; Address; Alcohol consumption; Area; Chronic; Clinical Trials; Collaborations; Communities; Consult; Country; Development; Discipline; Disease; Drug usage; Early Intervention; Educational workshop; Etiology; European; Faculty; Fellowship; Forensic Psychiatry; Future; Glean; Goals; Home environment; Illicit Drugs; Intervention; Knowledge; Learning; Life Cycle Stages; Longevity; Mentors; Michigan; Physicians; Postdoctoral Fellow; Prevention strategy; Psychiatry; Psychopathology; Research; Research Infrastructure; Research Institute; Research Methodology; Research Personnel; Research Project Grants; Research Training; Resources; Science; Scientist; Site; Societies; Specificity; Staging; Substance Use Disorder; Substance abuse problem; Techniques; Testing; Time; Training; Ukraine; United States National Institutes of Health; Universities; Work; addiction; base; career; cost; design; disorder prevention; experience; infrastructure development; interest; intervention program; programs; screening; social; working group

DESCRIPTION (provided by applicant): Substance use disorders (SUDs) are chronic, recurring disorders of major cost to society at all stages of the life cycle. They are of particula concern in Ukraine, whose rate of alcohol use is 5th highest in the world and whose lifetime rate of illicit drug use is already 21% by age 16 (WHO, 2011). At the same time, because of long periods of political turmoil and limited national resources, intervention programming to address these issues is primarily focused on chronic, end stage disorder, and concomitant professional training and addiction science have a similar focus. Both developmental/etiologic science and the intervention programming derivative from that are absent, although a small subset of researchers familiar with developments over the past decade in western countries have been appreciative of this changed perspective, and have been looking for ways to import it. Working in collaboration with two nationally visible physician scientists (MD/PhDs) from this cadre, and drawing on the experience gleaned from a successful program of substance abuse research infrastructure development in other Eastern European countries over the last 10 years, this project would implement a set of substance abuse research training experiences at several different levels of specificity, duration, and focus. The content goal is for transfer of knowledge pertaining to the developmental etiology of SUDs and implementation of intervention techniques that build upon that scientific base. In the latter years of the program, we would mentor and collaborate in design and pilot testing of an early screening and intervention program that ultimately will have the potential for national dissemination. The proposed program involves collaboration among faculty from 16 disciplines at the University of Michigan (UM), Department of Psychiatry (Addiction Research Center), at the Ukrainian Scientific Research Institute of Social, Forensic Psychiatry and Narcology (USRISFPN), and at the National University of Kyiv- Mohyla Academy (NUKMA). A set of interlocking training experiences at different levels of intensity and career status will include the following: (a) Yearly workshops (~ 35 attendees) held in various sites in Ukraine, for all levels of post-doctoral substance abuse scientists interested n the developmental psychopathology of SUD, research methodology, and SUD prevention and intervention strategies in non-clinical or community-based settings. (b) Year-long fellowships at UM, for 5 early-career post-doctoral fellows to learn more research methodology and work with mentors in areas of common interest, (c) Home-country research projects that these fellows develop while in the U.S., (d) 3 intermediate-term fellowships at UM for mid-career substance abuse researchers. (e) 3 short-term fellowships for senior research faculty to consult at UM and NIH about future program directions. (f) Creation of a Research/Intervention Program working group to develop a clinical trial on SUD screening and early intervention in targeted communities; and (g) Support of increased scientific collaboration between Ukrainian substance abuse researchers and other Eastern European researchers.

描述(由申请人提供)：物质使用障碍(SODS)是一种慢性、复发性疾病，在生命周期的所有阶段都会给社会带来重大损失。他们在乌克兰尤其令人担忧，该国的酒精使用率在世界上排名第五，到16岁时，该国的终身非法吸毒率已经达到21%(世卫组织，2011年)。与此同时，由于长期的政治动荡和有限的国家资源，解决这些问题的干预方案主要侧重于慢性终末期障碍，伴随而来的专业培训和成瘾科学也有类似的重点。发育/病因学和由此衍生的干预规划都没有，尽管一小部分熟悉西方国家过去十年发展的研究人员对这种改变的观点表示赞赏，并一直在寻找方法将其引入。该项目与这一干部中的两名全国可见的内科科学家(医学博士/博士)合作，并借鉴过去10年从其他东欧国家药物滥用研究基础设施发展的成功方案中收集的经验，将在几个不同的具体、持续时间和重点水平上实施一套药物滥用研究培训经验。内容的目标是知识的转移 关于肥胖症的发育性病因学和建立在此科学基础上的干预技术的实施。在该计划的最后几年，我们将指导和合作设计和试点测试一项早期筛查和干预计划，该计划最终将具有在全国传播的潜力。拟议的计划涉及密歇根大学(UM)、精神病学系(成瘾研究中心)、乌克兰社会、法医精神病学和精神病学科学研究所(USRISFPN)以及基辅-莫希拉国立大学(NUKMA)16个学科的教职员工之间的合作。一套针对不同强度和职业状况的连锁培训经验将包括：(A)在乌克兰的不同地点为所有级别的博士后药物滥用科学家举办年度讲习班(约35人)，这些科学家对非临床或社区环境中的SUD发展精神病理学、研究方法以及SUD预防和干预战略感兴趣。(B)在密歇根大学为5名职业生涯早期的博士后研究员提供为期一年的奖学金，以学习更多的研究方法，并在共同感兴趣的领域与导师合作；(C)这些研究员在美国期间开发的母国研究项目；(D)在密歇根大学为职业生涯中期的药物滥用研究人员提供的3个中期奖学金。(E)提供3个短期研究金，供高级研究人员在密歇根大学和国立卫生研究院就未来的方案方向进行咨询。(F)设立一个研究/干预方案工作组，以便在目标社区开展关于严重急性呼吸窘迫综合征筛查和早期干预的临床试验；(G)支持加强乌克兰药物滥用研究人员与其他东欧研究人员之间的科学合作。