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中文摘要
翻译
描述(由申请人提供):本提案响应慢性非传染性疾病和终生失调(CNCD)福格蒂倡议,重点关注印度三个正在遭受城市化严重有害影响的地区:印度东北部(阿萨姆邦和锡金)和印度中南部(卡纳塔克邦)。这份福格蒂报告的目标与福格蒂战略计划的目标一致,即缩小培训差距和提高非传染性疾病的研究能力,并将重点放在那些尽管在中低收入国家日益加重疾病负担却很少受到关注的行为状况上。该方案涉及接触暴力、成瘾(处方药和非法药物、酒精和尼古丁)以及最具破坏性的精神症状(精神病、自杀意念和痴呆)。它还强调在整个生命周期中对疾病的社会决定因素(环境和社会因素)以及表观遗传决定因素进行培训。这个新项目将加强和扩大Fogarty ICOHRTA项目所开展的工作。Fogarty ICOHRTA项目于2001年开始资助,由华盛顿大学的Linda Cottler博士和主要外国合作者印度卡纳塔克邦邦班加罗尔国家精神卫生和神经科学研究所(NIMHANS)的Sanjeev Jain博士指导。根据疾病控制和预防机制,我们正在增加两个新机构,具体来说,是阿萨姆邦提斯普尔Lokopriya Gopinath Bordoloi (LGBRIMH)地区精神卫生研究所和锡金甘托克志愿卫生协会。增加这些项目是为了增加我们与主要非政府组织机构合作培训的公共卫生和政策重点。印度-美国团队已经在建立研究能力方面取得了相当大的进展,由班加罗尔NIMHANS培训的精神卫生专业人员与吴的精神病学部门合作;这个新的Fogarty项目使WU和NIMHANS有机会继续建设所需的公共卫生相关研究能力,同时也与锡金东北部地区和阿萨姆邦地区建立联系,这些地区迫切需要可持续的研究能力建设和外联指导。我们计划在5年内每年培养4名长期实习生,其中2名博士预科生,2名博士后。培训咨询小组(TAG)将对学员的选择和进展进行评估,该小组将就与印度培训讲习班的重点有关的问题以及各机构之间和各机构之间更多合作赠款的想法向主任和主要外国合作者提供反馈。这个项目的学员将有机会参加正式课程,参加研讨会和辅导,并与他们的导师一起以学徒的方式工作。培训负责任的研究行为是该计划的主要重点。通过我们扩大的项目,我们将在印度的三个地点(其中一个能力有所提高,另外两个急需基础设施建设)和我们新的重点网络建立可持续的伙伴关系,对世界上一些负担最重的疾病进行干预。
英文摘要
DESCRIPTION (provided by applicant): This proposal, responding to the Chronic Non-Communicable Diseases and Disorders Across the Lifespan (CNCD) Fogarty initiative, focuses on three locations in India that are experiencing acute, detrimental effects of urbanization: Northeast India (Assam and Sikkim) and South Central India (Karnataka). The goals of this Fogarty submission align with the Fogarty Strategic Plan to reduce the training gap and increase research capacity for CNCDs, and focuses on behavioral conditions that receive little attention even though they are increasingly contributing to the burden of disease in Lower and Middle Income Countries (LMICs). This program addresses exposure to violence, addiction (prescribed and illicit drugs, alcohol and nicotine), and the most impairing mental symptoms (psychosis, suicidal ideation and dementia). It also emphasizes training in the social determinants of illness (environmental and social factors), as well as epigenetic determinants, across the lifespan. This new program will enhance and expand the work conducted through a sunsetted Fogarty ICOHRTA Program, funded since 2001, directed by Dr. Linda Cottler from Washington University and Major Foreign Collaborator Dr. Sanjeev Jain from the National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, Karnataka, India. Under the CNCD mechanism, we are adding two new institutions, specifically, Lokopriya Gopinath Bordoloi (LGBRIMH) Regional Institute of Mental Health in Tezpur, Assam and the Voluntary Health Association of Gangtok, Sikkim (VHAS). These programs are added to increase the public health and policy emphasis of our training collaborating with premier NGO institutions. The INDO-US team has already made considerable progress building research capacity with mental health professionals trained by NIMHANS in Bangalore paired with WU's Department of Psychiatry; this new Fogarty gives WU and NIMHANS the opportunity to continue building needed public health relevant research capacity while also bridging to Northeast areas of Sikkim and Assam-areas that have critical need for sustainable research capacity building and outreach mentoring. We propose to train 4 long term trainees-2 pre docs and 2 post docs-every year for 5 years. Trainee selection and progress will be evaluated by the Training Advisory Group (TAG), who will give feedback to the Director and Major Foreign Collaborator on issues relating to the focus of training workshops in India and ideas for more collaborative grants between and across the institutions. Trainees in this program will have the opportunity to take formal courses, attend seminars and tutorials and work with their mentors apprenticeship- style. Training in the responsible conduct of research is a major emphasis of this program. Through our expanded program with three Indian sites, one with increased capacity, and two in critical need of infrastructure building, and our new networks of focus, we will develop sustainable partnerships to intervene with some of the most burdensome CNCDs in the world.
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Patterns and neurocognitive consequences of opioid-alcohol polysubstance use
  • 批准号:
    10659347
  • 项目类别:
  • 资助金额:
    $44.78万
  • 财政年份:
    2023
  • 负责人:
    Linda B. Cottler
  • 依托单位:
All of Us Consortium of CTSA Community Engagement Programs
  • 批准号:
    10799349
  • 项目类别:
  • 资助金额:
    $186.3万
  • 财政年份:
    2022
  • 负责人:
    Linda B. Cottler
  • 依托单位:
All of Us Consortium of CTSA Community Engagement Programs
  • 批准号:
    10307020
  • 项目类别:
  • 资助金额:
    $186.3万
  • 财政年份:
    2022
  • 负责人:
    Linda B. Cottler
  • 依托单位:
Integrating Wastewater-Based Epidemiology into the National Drug Early Warning System Coordinating Center to Track Community Health Trends
  • 批准号:
    10375878
  • 项目类别:
  • 资助金额:
    $15.25万
  • 财政年份:
    2021
  • 负责人:
    Linda B. Cottler
  • 依托单位:
海外基金