Administrative Supplement for Gulf Coast Center for Precision Environmental Health

摘要：总体 休斯顿-加尔维斯顿地区是十几个超级基金网站的所在地，也是这家石化公司的枢纽 该行业拥有500家化工厂、10家炼油厂和6000英里长的石油、天然气和化工管道 成为该国最大的能源走廊。该地区也是世界上最大的医疗中心所在地， 德克萨斯医疗中心。因此，NIEHS环境健康的需求和机会的大小 科学(EHS)核心中心(EHS-CC)在这个地区很棒。作为德克萨斯医疗中心的EHS-CC， 墨西哥湾沿岸精准环境健康中心(GC-CPEH)将成为 有影响力的EHS研究，与当地社区和利益相关者的多方向沟通，以及 发动机驱动翻译的精准环境健康研究进展，以改善人类健康。这个 GC-CPEH的目标是：整合和催化跨学科和有影响力的EHS研究 德克萨斯医学中心的机构，并促进下一代EHS研究人员；2：提供 机构获取资源和尖端技术，以加速翻译和逆转 翻译，改善人类环境健康的研究进展；3：支持和增强能力 通过将社区利益相关者和调查人员联系起来，在墨西哥湾沿岸地区开展社区参与 为GC-CPEH研究提供信息的多方向交流活动；4：实现快速反应研究 墨西哥湾沿岸地区环境灾难期间和之后的活动。GC-CPEH有34个满载 成员，其中17人拥有NIEHS资助的积极赠款支持，每年直接资助基数为500万美元。 该中心将通过其主题重点领域：早期生活支持精确的环境健康研究 遗传和表观遗传环境的相互作用；人类环境中的机制和干预 疾病；以及灾害研究应对。GC-CPEH还将通过其试点项目促进研究 计划，通过管道无缝访问下一代技术，加快研究进展 设施核心和将促进翻译研究的IHSFC；由导航员和 配套资金核心利用计划。管理核心，由经验丰富的EHS组成 领导者，为初级教员提供组织基础设施和指导，包括职业生涯 发展领袖培训计划，以促进研究和专业领导力的发展 技能。一个经验丰富、充满活力的CEC将促进与社区和 利益攸关方，并为墨西哥湾沿岸地区的环境卫生政策提供信息。

ABSTRACT: OVERALL The Houston-Galveston area is home to over a dozen Superfund sites, and is a hub for the petrochemical industry with 500 chemical plants, 10 refineries and >6000 miles of oil, gas and chemical pipelines in what has become the country’s largest energy corridor. The area is also home to the largest medical center in the world, the Texas Medical Center. Thus, both the need, and size of the opportunity, for an NIEHS Environmental Health Sciences (EHS) Core Center (EHS-CC) in this region is great. As the EHS-CC for the Texas Medical Center, the Gulf Coast Center for Precision Environmental Health (GC-CPEH) will be the focal point and catalyst for impactful EHS research, multi-directional communication with local communities and stakeholders, and the engine driving translation of precision environmental health research advances to improve human health. The Goals for the GC-CPEH are to 1: Integrate and catalyze impactful EHS research across disciplines and institutions of the Texas Medical Center, and promote the next-generation of EHS researchers; 2: Provide inter- institutional access to resources and cutting-edge technologies to accelerate translation, and reverse translation, of research advances to improve human environmental health; 3: Support and empower community engagement across the Gulf Coast region by linking community stakeholders and investigators in multi-directional communication activities that inform GC-CPEH research; 4: Enable rapid response research activities during and after environmental disasters in the Gulf Coast region. The GC-CPEH has 34 Full members, 17 of whom have active NIEHS-funded grant support with an annual direct funding base >$5 million. The Center will support precision environmental health research through its Thematic Focus Areas: Early Life Genetic and Epigenetic Environment Interactions; Mechanisms and Interventions in Human Environmental Disease; and Disaster Research Response. The GC-CPEH will also promote research through its Pilot Project Program, accelerate research advances with seamless access to Next-gen technologies via the PIPELINE Facility Core and an IHSFC that will promote translational research; activities facilitated by Navigators and the Matching Funds Core Utilization Program. The Administrative Core, composed of highly seasoned EHS leaders, provides organizational infrastructure, and mentoring for junior faculty that includes a Career Development Leaders-in-Training program to promote development of research and professional leadership skills. An experienced and vibrant CEC will foster multi-directional communication with communities and stakeholders, and inform environmental health policy for the Gulf Coast Region.