FASEB SRC on Renal Hemodynamics: Integrating with the nephron and beyond

描述(由申请者提供)：2013年FASEB夏季研究会议主题为“肾血流动力学：与肾单位的整合及超越”，将于2013年6月30日至7月5日在佛蒙特州萨克斯顿河的佛蒙特学院举行。这次会议非常成功，以前有很多人参加，每三年举行一次，将为多学科科学家提供一个论坛，在非正式、随意和轻松的气氛中会面并公开讨论他们目前对肾脏相关疾病的最新创新、翻译和基础研究。我们为会议开发了一种新的高度互动的形式，以增加讨论和海报会议的时间，这将促进更深入的互动，特别是在成熟的和职业生涯早期的调查人员之间。这包括两次“数据利尿”会议，在海报会议之前，海报以快速格式口头展示。这在其他会议上也得到了应用，并成功地激发了人们对海报的兴趣。此外，在集体聚餐期间，高级调查员将被要求与初级调查员坐在一起。 不是来自他们自己的机构。这种非正式的环境允许更多的思想交流 以及职业发展。会议的目标是：1)召集一个国际公认的多学科研究小组，介绍和讨论肾脏血流动力学机制领域的最新研究成果，这些机制是高血压、糖尿病、肥胖症、代谢综合征、肾小球硬化和肾病等疾病的原因或结果；2)促进职业生涯早期研究人员的参与；以及3)促进妇女和代表性不足的少数群体的参与。我们将通过有针对性的招聘和旅行奖励，启动早期职业调查人员、妇女和少数族裔的参与。为此目的，我们大大增加了这些群体作为受邀发言者和会议主持人的参与度，在以往的会议上，至少有一半的受邀发言者以前没有发言或至少12年没有发言。此外，所有的数据利尿会议将是新的调查人员。具体内容包括：高血压和糖尿病的肾血管功能障碍；钠处理的新机制；导致高血压和肾脏疾病的肾脏炎症；自我调节和肾小管-血管沟通机制；高血压和肾功能的性别差异；血管紧张素系统功能的新机制；表观遗传学和妊娠高血压综合征和肾功能障碍；活性氧物种；缺氧和缺血性损伤；以及肾脏髓质血流动力学。

DESCRIPTION (provided by applicant): The 2013 FASEB Summer Research Conference on "Renal Hemodynamics: Integrating with the nephron and beyond" will take place on June 30 through July 5, 2013 at Vermont Academy, Saxtons River, VT. This highly successful, previously well-attended, recurring meeting, held once every three years, will provide a forum for multidisciplinary scientists to meet and openly discuss their most current innovative, translational and basic research on kidney-related diseases in an informal, casual, relaxed atmosphere. We have developed a new, highly interactive format for the meeting to increase the amount of time for discussion and poster sessions which will foster more in-depth interactions especially between established and early career investigators. This includes two "data diuresis" sessions where posters are presented orally in a rapid-fire format prior to the poster session. This has been used at other conferences and successfully stimulates interest in the posters. Also, during the group dinners, senior investigators will be asked to sit with junior investigators that are not from their own institution. This informal setting allows for greater exchange of ideas as well as professional development. Conference aims are: 1) to convene an internationally recognized multidisciplinary group of investigators to present and discuss current research findings in the area of renal hemodynamic mechanisms that are the cause or consequence of diseases including hypertension, diabetes, obesity, metabolic syndrome, glomerular sclerosis and nephropathy; 2) to promote the participation of early career investigators; and 3) to promote the participation of women and under-represented minorities. We will initiate participation of early career investigators, women and minorities through targeted recruitment and travel awards. To this end, we have significantly increased participation by these groups as invited speakers and session moderators over previous conferences, at least half of the invited speakers have not presented before or have not presented in at least 12 years. Furthermore, all of the data diuresis sessions will be new investigators. Specific areas to be covered include: renal vascular dysfunction in hypertension and diabetes; novel mechanisms of sodium handling; renal inflammation as a cause of hypertension and renal disease; mechanisms of autoregulation and tubular-vascular communication; sex differences in hypertension and renal function; novel mechanisms of angiotensin system function; epigenetics and pregnancy induced hypertension and renal dysfunction; reactive oxygen species; hypoxia and ischemic injury; and renal medullary hemodynamics.