Cardiovascular Phenotyping Core B
心血管表型分析核心 B
基本信息
- 批准号:10555123
- 负责人:
- 金额:$ 24.01万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-02-15 至 2028-01-31
- 项目状态:未结题
- 来源:
- 关键词:AliquotAmbulatory Blood Pressure MonitoringAnimal ModelAreaBlood PressureBlood VesselsBlood specimenCardiovascular PhysiologyCardiovascular systemCellsChronicClinicComputer softwareDataData AnalysesData Storage and RetrievalElectronic MailEnsureFrequenciesGoalsGuidelinesHealthHeart RateHourHumanHuman ResourcesIndividualLifeMeasurementMeasuresMethodsMonitorMotor ActivityOutcomeParticipantPatternPeriodicityPeripheral Blood Mononuclear CellPhasePhenotypePhysiciansPhysiologic pulsePlasmaPlayProceduresQuality ControlReproducibilityResearch PersonnelResourcesRodentRodent ModelRoleRural CommunitySamplingScientistServicesStatistical Data InterpretationStressStructureSupervisionTelemetryTemperatureTimeTrainingValidationWorkbiobankblood pressure variabilitycardiovascular disorder riskcardiovascular risk factorcircadiandata acquisitionearly life stressexperienceheart rate variabilityhuman subjectin vivomeetingsmonocytemultiple omicsperipheral bloodprogramsremote locationresiliencesynergismultrasound
项目摘要
CARDIOVASCULAR PHENOTYPING CORE B SUMMARY
The primary goal and function of Core B is to provide services to the individual projects within the Program
Project related to measures of cardiovascular function. The objective of Core B is to serve basic support
services separated into three functional areas: 1) 24-hour blood pressure analysis in rodent models; 2)
ambulatory and clinic blood pressure measurements and validation in human participants; and 3) pulse wave
velocity and pulse wave analysis assessments in human subjects. We will also monitor quality control and
reproducibility in cardiovascular measurements in both animal models and human subjects for maximum
efficiency and rigor. Core B is structured to provide the highest degree of quality control and allow for
consistency across all of the individual projects of the Program Project. This involves very closely coordinated
efforts and sharing of expertise between the projects. Drs. David Pollock and Eric Judd will oversee Core B.
Dr. Pollock has many years of experience coordinating large scale in vivo studies in rodents with over 20 years
of conducting chronic blood pressure measurements by telemetry. Dr. Judd has directed a wide range of
cardiovascular phenotyping studies in human subjects for over 10 years. This includes ambulatory blood
pressure monitoring, vascular stiffness measurements via pulse wave velocity and pulse wave analysis. Core
services will be tightly maintained with weekly contacts by email and monthly meetings to discuss how well
Core B is functioning to meet the needs of the PPG and any issues that may have developed. The aims of
Core B are: 1) Provide circadian analysis of 24-hour telemetry data in rodent models, 2) Provide frequency and
time domain analysis for assessment of autonomic function in rodent models, 3) Provide supervision of clinic
and ambulatory blood pressure measurements and consistent data acquisition and analysis, 4) Perform pulse
wave velocity assessments, 5) Liaison with Core C to provide statistical analysis of cardiovascular data, and 6)
Liaison with Core A to facilitate data storage.
心血管表型分析核心 B 总结
核心 B 的主要目标和功能是为计划内的各个项目提供服务
与心血管功能测量相关的项目。核心B的目标是提供基础支持
服务分为三个功能领域:1)啮齿动物模型的 24 小时血压分析; 2)
人类参与者的动态和临床血压测量和验证; 3) 脉搏波
对人体进行速度和脉搏波分析评估。我们还将监控质量控制和
动物模型和人类受试者的心血管测量的再现性最大化
效率和严谨。核心 B 的结构可提供最高程度的质量控制并允许
计划项目的所有单个项目的一致性。这涉及非常密切的协调
项目之间的努力和专业知识共享。博士。 David Pollock 和 Eric Judd 将监督 Core B。
Pollock 博士拥有 20 多年协调啮齿动物大规模体内研究的经验
通过遥测进行慢性血压测量。贾德博士指导了广泛的
对人类受试者的心血管表型研究已有 10 多年的历史。这包括动态血液
压力监测、通过脉搏波速度和脉搏波分析测量血管硬度。核
服务将得到严格维护,每周通过电子邮件进行联系,每月举行一次会议来讨论服务质量
核心 B 的作用是满足 PPG 的需求以及可能出现的任何问题。的目标
核心 B 是:1) 提供啮齿动物模型中 24 小时遥测数据的昼夜节律分析,2) 提供频率和
用于评估啮齿动物模型自主神经功能的时域分析,3) 提供临床监督
和动态血压测量以及一致的数据采集和分析,4) 执行脉搏测量
波速评估,5) 与 Core C 联络以提供心血管数据的统计分析,以及 6)
与Core A联络以方便数据存储。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
DAVID M POLLOCK其他文献
DAVID M POLLOCK的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('DAVID M POLLOCK', 18)}}的其他基金
Deep South KUH Premier Research - Interdisciplinary Mentored Education (PRIME) Training Core
深南 KUH Premier Research - 跨学科指导教育 (PRIME) 培训核心
- 批准号:
10889499 - 财政年份:2023
- 资助金额:
$ 24.01万 - 项目类别:
Timing of Diet and Kidney Pathophysiology in Diet-Induced Obesity
饮食引起的肥胖的饮食时机和肾脏病理生理学
- 批准号:
10735631 - 财政年份:2023
- 资助金额:
$ 24.01万 - 项目类别:
Integrating novel mechanisms controlling sodium excretion and blood pressure
整合控制钠排泄和血压的新机制
- 批准号:
9922350 - 财政年份:2017
- 资助金额:
$ 24.01万 - 项目类别:
Integrating novel mechanisms controlling sodium excretion and blood pressure
整合控制钠排泄和血压的新机制
- 批准号:
10267370 - 财政年份:2017
- 资助金额:
$ 24.01万 - 项目类别:
FASEB SRC on Renal Hemodynamics: Integrating with the nephron and beyond
FASEB SRC 肾血流动力学:与肾单位及其他领域的整合
- 批准号:
8528300 - 财政年份:2013
- 资助金额:
$ 24.01万 - 项目类别:
ENDOTHELIN CONTROL OF RENAL HEMODYNAMIC AND EXCRETORY FUNCTION
内皮素对肾脏血流动力学和排泄功能的控制
- 批准号:
8464198 - 财政年份:2010
- 资助金额:
$ 24.01万 - 项目类别:
ENDOTHELIN CONTROL OF RENAL HEMODYNAMIC AND EXCRETORY FUNCTION
内皮素对肾脏血流动力学和排泄功能的控制
- 批准号:
8125044 - 财政年份:2010
- 资助金额:
$ 24.01万 - 项目类别:
ENDOTHELIN CONTROL OF RENAL HEMODYNAMIC AND EXCRETORY FUNCTION
内皮素对肾脏血流动力学和排泄功能的控制
- 批准号:
8661220 - 财政年份:2010
- 资助金额:
$ 24.01万 - 项目类别:
ENDOTHELIN CONTROL OF RENAL HEMODYNAMIC AND EXCRETORY FUNCTION
内皮素对肾脏血流动力学和排泄功能的控制
- 批准号:
8266432 - 财政年份:2010
- 资助金额:
$ 24.01万 - 项目类别:
相似海外基金
Wearable Micro-Structured Tonometric Sensor Patches for 24-Hour Ambulatory Blood Pressure Monitoring
用于 24 小时动态血压监测的可穿戴微结构张力传感器贴片
- 批准号:
10680575 - 财政年份:2022
- 资助金额:
$ 24.01万 - 项目类别:
Wearable Micro-Structured Tonometric Sensor Patches for 24-Hour Ambulatory Blood Pressure Monitoring
用于 24 小时动态血压监测的可穿戴微结构张力传感器贴片
- 批准号:
10509575 - 财政年份:2022
- 资助金额:
$ 24.01万 - 项目类别:
Deriving 24-hour Ambulatory Blood Pressure Monitoring reference values for SouTh AsiaN Children (ABPM-STANCE)
得出南亚儿童 24 小时动态血压监测参考值 (ABPM-STANCE)
- 批准号:
445882 - 财政年份:2021
- 资助金额:
$ 24.01万 - 项目类别:
Operating Grants
Evaluation of Pathophysiology in Heart Failure Patients Using New ICT-based Multisensor Ambulatory Blood Pressure Monitoring
使用基于 ICT 的新型多传感器动态血压监测评估心力衰竭患者的病理生理学
- 批准号:
21K20910 - 财政年份:2021
- 资助金额:
$ 24.01万 - 项目类别:
Grant-in-Aid for Research Activity Start-up
Ambulatory blood pressure monitoring during hot-water bathing in winter using radial pulse wave acquisition device
利用径向脉搏波采集装置监测冬季热水洗澡时的动态血压
- 批准号:
18K15899 - 财政年份:2018
- 资助金额:
$ 24.01万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Association between 24 hour ambulatory blood pressure monitoring and postoperative cardiac function in patients with sleep apnea syndrome
睡眠呼吸暂停综合征患者24小时动态血压监测与术后心功能的关系
- 批准号:
26670679 - 财政年份:2014
- 资助金额:
$ 24.01万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Exercise program for the patients with cardiovascular disease using ambulatory blood pressure monitoring equipped with actigraphy
使用体动记录仪动态血压监测对心血管疾病患者进行运动计划
- 批准号:
25461065 - 财政年份:2013
- 资助金额:
$ 24.01万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
To clarify the new factors affecting change in blood pressure in acute stroke patients using ambulatory blood pressure monitoring and actigraphy
利用动态血压监测和体动记录仪阐明影响急性脑卒中患者血压变化的新因素
- 批准号:
24790894 - 财政年份:2012
- 资助金额:
$ 24.01万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
IMPACT OF AMBULATORY BLOOD PRESSURE MONITORING ON LIVING KIDNEY DONATION
动态血压监测对活体肾捐献的影响
- 批准号:
7953663 - 财政年份:2009
- 资助金额:
$ 24.01万 - 项目类别:
COMPARISON OF 24-HOUR AMBULATORY BLOOD PRESSURE MONITORING BETWEEN DIFFERENT
不同设备之间24小时动态血压监测的比较
- 批准号:
7950895 - 财政年份:2008
- 资助金额:
$ 24.01万 - 项目类别: