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Inheritance of DNA methylation state in humans

Inheritance of DNA methylation state in humans
人类DNA甲基化状态的遗传
批准号:
nhmrc : 1010374
负责人:
Dr Allan Mcrae
金额:
$48.17万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2014-12-31

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中文摘要
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英文摘要
In the study of common disease, it is becoming apparent that it is not only an individual's DNA sequence that can encode susceptibility to disease, but also chemical modifications to that sequence. Despite the importance of these chemical modifications in the development of disease, there has been no comprehensive survey of the extent which they are transmitted across generations in humans. This proposal will investigate how one of those modifications, DNA methylation, is inherited.
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