Genome-wide Association Study for Genes That Determine Environmental Sensitivity in Cardiovascular Disease Risk

决定心血管疾病风险环境敏感性的基因的全基因组关联研究

• 批准号: nhmrc : 496719
• 负责人: Dr Allan Mcrae
• 金额: $ 19.16万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/genome-wide-association-disease-risk/115492
• 关键词: Genome; wide; Association; Study; Genes

There are many known lifestyle and environmental influences for the development of cardiovascular disease. But are there genes that control how susceptible an individual is to these environmental influences? Discovery of such genes could have far greater implications for the prevention and treatment of disease than genes which simply affect levels of the trait. This project will identify genes that affect the environmental susceptibility for cardiovascular disease risk factors.

有许多已知的生活方式和环境影响心血管疾病的发展。但是，是否有基因控制着个体对这些环境影响的敏感程度？这些基因的发现对于疾病的预防和治疗可能比仅仅影响性状水平的基因具有更大的意义。该项目将确定影响心血管疾病风险因素环境易感性的基因。