Genome-wide Association Study for Genes That Determine Environmental Sensitivity in Cardiovascular Disease Risk

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There are many known lifestyle and environmental influences for the development of cardiovascular disease. But are there genes that control how susceptible an individual is to these environmental influences? Discovery of such genes could have far greater implications for the prevention and treatment of disease than genes which simply affect levels of the trait. This project will identify genes that affect the environmental susceptibility for cardiovascular disease risk factors.