Methods and software tool for complex trait analyses using multi-omics data

使用多组学数据进行复杂性状分析的方法和软件工具

• 批准号: nhmrc : 1107258
• 负责人: Dr Allan Mcrae
• 金额: $ 39.57万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/methods-software-tool-multi-omics/662969
• 关键词: Methods; software; tool; complex; trait

This project aims to develop methods to disentangle the contribution of people’s difference in DNA sequence, DNA methylation, and gene expression to their difference in characteristics (including risks to diseases), and to utilise these information to predict disease risks of different people. This project also aims to develop a versatile and efficient computer software to implement the methods being proposed in this project, as well as all other commonly used methods in the research community.

该项目旨在开发各种方法，以找出人们在DNA序列、DNA甲基化和基因表达上的差异对他们特征差异(包括对疾病的风险)的影响，并利用这些信息来预测不同人的疾病风险。该项目还旨在开发一种通用和高效的计算机软件，以实施该项目中提出的方法以及研究界所有其他常用的方法。