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中文摘要
翻译
NEI的组织学核心致力于支持患者护理,视力研究以及NEI和NIH其他合作机构的使命。这包括处理手术中取出的人体组织(主要是眼部组织)和尸检时收集的组织。Core对组织、切片和染色载玻片进行大体检查,以进行光学和/或透射电子显微镜检查。组织学核心服务于临床分支和NEI校内研究计划下的所有NEI实验室,以及其他NIH研究所,这些研究所进行涉及眼部和相关组织的研究。此外,该中心还接收NIH以外(美国和国外)的临床医生和研究人员提交的临床和实验标本,以进行咨询或合作。在2013财年,组织学核心收到并处理了约5076份标本,并产生了超过6153张染色切片。此外,实验室还处理了送往超微结构的病例材料,产生了4208张电子显微镜图像。本财政年度还收到并处理了91个临床病例。患者标本产生2113个组织学切片和173个电子显微镜图像。有20多份出版物收录了核心小组开展的工作。 虽然我们95%的工作是致力于NEI的职责,但组织学核心也为NIH内外的研究项目提供服务。核心遵循NIH内部研究计划的研究指导方针和NIH制定的其他标准。
英文摘要
The Histopathology Core of the NEI is devoted to supporting the patient care, vision research, and mission of the NEI and other collaborative institutes at the NIH. This consists of processing human tissues (mainly ocular tissues) removed in surgeries and collected at autopsies. The Core grosses the tissues, sections and stains slides for light and/or transmission electron microscopy. The Histopathology Core serves the Clinical Branch and all NEI laboratories under the NEI Intramural Research Program, as well as other NIH institutes, which perform research involving ocular and related tissues. In addition, the Core receives clinical and experimental specimens submitted by clinicians and investigators outside NIH (USA and abroad) for consultation or collaboration. During FY13, the Histopathology Core received and processed approximately 5076 specimens and yielded over 6153 slides stained. Additionally, the laboratory processed case materials sent for ultrastructure, which produced 4208 electron microscopic images. This fiscal year, 91 clinical cases were also received and processed. The patient specimens produced 2113 histological slides and 173 electronic microscopic images. There are over 20 publications that include work performed by the Core. Although about 95% of our effort is devoted to NEI duties, the Histopathology Core also performs services for research projects inside and outside the NIH. The core follows the guidelines for the conduct of research in the intramural research program at the NIH and other standards set by the NIH.
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Molecular And Immunopathology Of Experimental And Clinical Ocular Diseases
  • 批准号:
    8938289
  • 项目类别:
  • 资助金额:
    $87.77万
  • 财政年份:
    --
  • 负责人:
    Chi-Chao Chan
  • 依托单位:
IMMUNOPATHOLOGY IN EYES WITH EXPERIMENTAL AND CLINICAL OCULAR DISEASES
  • 批准号:
    6106829
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    Chi-Chao Chan
  • 依托单位:
Histopathology Core
  • 批准号:
    8938505
  • 项目类别:
  • 资助金额:
    $53.92万
  • 财政年份:
    --
  • 负责人:
    Chi-Chao Chan
  • 依托单位:
Histology Core
  • 批准号:
    7734659
  • 项目类别:
  • 资助金额:
    $41.58万
  • 财政年份:
    --
  • 负责人:
    Chi-Chao Chan
  • 依托单位:
国内基金
海外基金
分化肌细胞脱细胞ECM-cells sheet 3D 支架构建及其促进容积性肌组织缺损再 生修复应用及机制研究
库否细胞(Kupffer cells)受体PirB/LILRB2在非酒精性脂肪性肝炎中的作用及机制研究
  • 批准号:
    82470907
  • 项目类别:
    面上项目
  • 资助金额:
    48.00万元
  • 批准年份:
    2024
  • 负责人:
    余学锋
  • 依托单位:
CAFs-TAMs-tumor cells调控在HRHPV感染致癌中的作用机制研究及AI可追溯预测模型建立
  • 批准号:
    82072862
  • 项目类别:
    面上项目
  • 资助金额:
    56.0万元
  • 批准年份:
    2020
  • 负责人:
    徐云升
  • 依托单位:
S100A8/A9--Myeloid cells特异性可溶性表氧化物水解酶(sEH)基因敲除改善胰岛素抵抗的新靶点
  • 批准号:
    82070825
  • 项目类别:
    面上项目
  • 资助金额:
    53.0万元
  • 批准年份:
    2020
  • 负责人:
    徐西振
  • 依托单位: