Accommodation and Defocus in the Infant Visual System

描述(申请人提供)：视觉和神经视觉系统的后天发育都依赖于视觉体验。视觉体验可以由两只眼睛的视网膜图像中提供的信息来定义。这项拟议研究的目标是了解在正常发育、弱视和斜视时，视觉系统如何通过调节和收敛运动反应来控制这种视觉体验。有四个相互关联的项目：i)了解运动在较长时间内的表现，检验与当前关于整合经验对活动依赖过程的影响的理论相关的假设。Ii)确定在发育过程中用于产生调节和收敛运动反应的线索，检验与线索冗余以及斜视和弱视发展相关的假说。Iii)确定调节和屈光在斜视治疗中的作用，并检验有关术后控制这些运动反应的假说。了解弱视治疗过程中的视网膜视觉体验及其在成功治疗中的作用。

DESCRIPTION (provided by applicant): The postnatal development of both the optical and neural visual systems is dependent on visual experience. Visual experience can be defined by the information available in the retinal images in the two eyes. The goal of the proposed research is to understand how the visual system controls this visual experience with accommodation and vergence motor responses, in normal development, amblyopia and strabismus. There are four interrelated projects: i) To understand motor performance over extended periods of time, to test hypotheses related to current theories of the effects of integrated experience on activity-dependent processes. ii) To determine the cues used in generating accommodation and vergence motor responses during development, to test hypotheses related to cue redundancy and the development of strabismus and amblyopia. iii) To determine the role of accommodation and vergence in the management of strabismus and test hypotheses about the control of these motor responses after surgery. iv) To understand retinal visual experience during amblyopia therapy and its role in successful treatments.