Molecular Basis of Infectious Diseases

描述（由申请人提供）：传染病的分子基础（MBID）研究培训计划以来自三个休斯顿教育机构的16名教师导师为中心：德克萨斯大学休斯顿健康科学中心，贝勒医学院和德克萨斯A&M大学生物科学与技术研究所。在此更新申请中，要求为三名博士提供继续培训支持。学生和八名本科暑期研究生。MBID培训计划的总体目的是为学员提供：1）培养新科学家的最新概念和微生物学研究技术的最佳环境; 2）更好地了解临床传染病当前的挑战; 3）基础研究和临床应用之间“弥合差距”的知识和工具。这一培训补助金的基础是传染病分子基础小组，该小组于1996年首次成立。MBID已经发展成为一个由400多名来自休斯顿地区的教师、博士后研究员、研究生和工作人员组成的高度互动的小组，他们的主要兴趣是细菌感染的分子发病机制。构成该培训补助金核心的16名教师拥有高研究生产力和广泛合作的记录。在过去的十年里，他们指导了178名博士前和博士后学员，目前正在指导22名博士。学生和25名博士后。该培训计划基于强大的核心课程，密集和互动的研究经验，每月MBID会议，年度务虚会，每周研讨会和期刊俱乐部，以及转化研究和临床传染病培训。已经建立了一个夏季研究计划，以帮助招聘有前途的本科生（特别是代表性不足的少数民族[URM]学员）进入传染病研究的职业生涯。在最初的赠款期间，7名博士前学员中有3名，31名暑期本科学员中有10名是URM学生，因此有希望在即将到来的赠款期间继续取得成功。 相关性：这一持续的、成功的培训补助金的主要目标是为微生物学学员提供临床传染病和转化研究方面的额外知识，从而指导研究更快地解决重要的传染病问题。此外，该计划将继续招收高素质的少数民族学生，增加代表性不足的少数民族科学家在微生物学/传染病接口的前沿进行研究的比例。

DESCRIPTION (provided by applicant): The Molecular Basis of Infectious Disease (MBID) research training program is centered on 16 faculty mentors from three Houston educational institutions: the University, of Texas Health Science Center at Houston, Baylor College of Medicine, and the Texas A&M University Institute for Biosciences and Technology. In this renewal application, continued training support is requested for three Ph.D. students and eight undergraduate summer research students. The overall purpose of the MBID training program is to provide trainees 1) an optimal environment for training new scientists in the latest concepts and techniques in microbiological research; 2) a better understanding of current challenges in clinical infectious diseases; and 3) the knowledge and tools to 'bridge the gap' between basic research and clinical applications. The basis of this training grant is the Molecular Basis of Infectious Disease group, which was first formed in 1996. MBID has developed into highly interactive group of over 400 faculty, postdoctoral fellows, graduate students, and staff from the Houston area whose primary interest is in the molecular pathogenesis of bacterial infections. The 16 faculty members that form the core of this training grant have a record of high research productivity and extensive collaborations. They have mentored 178 predoctoral and postdoctoral trainees during the past ten years, and currently are mentoring 22 Ph.D. students and 25 postdoctoral fellows. The training program is based on a strong core curriculum, intensive and interactive research experiences, monthly MBID meetings, annual retreats, weekly seminars and journal clubs, and training in translational research and clinical infectious diseases. A summer research program has been established to aid in the recruitment of promising undergraduate students (and in particular underrepresented minority [URM] trainees) into careers in infectious disease research. During the initial grant period, 3 of 7 predoctoral trainees and 10 of 31 summer undergraduate trainees were URM students, thus promising continued success in this objective during the coming grant period. RELEVANCE: The major goal of this ongoing, successful training grant is to provide microbiology trainees additional knowledge in clinical infectious diseases and translational research, thereby directing research toward the more rapid resolution of important infectious disease problems. In addition, the program will continue to recruit highly qualified underrepresented minority students, increasing the proportion of underrepresented minority scientists performing research at the cutting edge of the microbiology/infectious disease interface.