Molecular Basis of Infectious Diseases

描述(由申请者提供)：传染病的分子基础(MBID)研究培训计划以来自三个休斯顿教育机构的16名教师导师为中心：休斯顿的德克萨斯大学健康科学中心、贝勒医学院和德克萨斯A&M大学生物科学与技术研究所。在这份续签申请中，要求为三名博士生和八名本科生暑期研究提供继续培训支持。MBID培训计划的总体目的是为学员提供1)培训新科学家掌握微生物研究的最新概念和技术的最佳环境；2)更好地了解临床传染病的当前挑战；3)基础研究和临床应用之间“弥合差距”的知识和工具。这笔培训赠款的基础是传染病分子基础小组，该小组成立于1996年。MBID已经发展成为由来自休斯顿地区的400多名教师、博士后研究员、研究生和工作人员组成的高度互动的小组，他们的主要兴趣是细菌感染的分子发病机制。构成这项培训拨款核心的16名教职员工都有很高的研究生产率和广泛的合作记录。在过去的十年中，他们已经指导了178名博士后和博士后实习生，目前正在指导22名博士生和25名博士后研究员。该培训计划以强大的核心课程、密集和互动的研究经验、每月MBID会议、年度务虚会、每周研讨会和期刊俱乐部以及翻译研究和临床传染病培训为基础。已经建立了一个暑期研究计划，以帮助招募有前途的本科生(特别是代表不足的少数族裔受训人员)进入传染病研究的职业生涯。在最初的资助期间，7名博士前实习生中有3名和31名夏季本科生中有10名是大学管理学院的学生，因此有望在即将到来的资助期间继续在这一目标上取得成功。 相关性：这一持续、成功的培训赠款的主要目标是向微生物学学员提供临床传染病和翻译研究方面的额外知识，从而指导研究更快地解决重要的传染病问题。此外，该项目将继续招收高素质的代表性不足的少数族裔学生，增加在微生物学/传染病界面的前沿进行研究的代表性不足的少数族裔科学家的比例。

DESCRIPTION (provided by applicant): The Molecular Basis of Infectious Disease (MBID) research training program is centered on 16 faculty mentors from three Houston educational institutions: the University, of Texas Health Science Center at Houston, Baylor College of Medicine, and the Texas A&M University Institute for Biosciences and Technology. In this renewal application, continued training support is requested for three Ph.D. students and eight undergraduate summer research students. The overall purpose of the MBID training program is to provide trainees 1) an optimal environment for training new scientists in the latest concepts and techniques in microbiological research; 2) a better understanding of current challenges in clinical infectious diseases; and 3) the knowledge and tools to 'bridge the gap' between basic research and clinical applications. The basis of this training grant is the Molecular Basis of Infectious Disease group, which was first formed in 1996. MBID has developed into highly interactive group of over 400 faculty, postdoctoral fellows, graduate students, and staff from the Houston area whose primary interest is in the molecular pathogenesis of bacterial infections. The 16 faculty members that form the core of this training grant have a record of high research productivity and extensive collaborations. They have mentored 178 predoctoral and postdoctoral trainees during the past ten years, and currently are mentoring 22 Ph.D. students and 25 postdoctoral fellows. The training program is based on a strong core curriculum, intensive and interactive research experiences, monthly MBID meetings, annual retreats, weekly seminars and journal clubs, and training in translational research and clinical infectious diseases. A summer research program has been established to aid in the recruitment of promising undergraduate students (and in particular underrepresented minority [URM] trainees) into careers in infectious disease research. During the initial grant period, 3 of 7 predoctoral trainees and 10 of 31 summer undergraduate trainees were URM students, thus promising continued success in this objective during the coming grant period. RELEVANCE: The major goal of this ongoing, successful training grant is to provide microbiology trainees additional knowledge in clinical infectious diseases and translational research, thereby directing research toward the more rapid resolution of important infectious disease problems. In addition, the program will continue to recruit highly qualified underrepresented minority students, increasing the proportion of underrepresented minority scientists performing research at the cutting edge of the microbiology/infectious disease interface.