Molecular Basis of Infectious Disease

描述（由申请人提供）：传染病分子基础（MBID）是一项研究培训计划，由来自休斯顿四所教育机构的18名教师导师组成：德克萨斯大学休斯顿健康科学中心，贝勒医学院，德克萨斯A&M大学生物科学与技术研究所和休斯顿大学学院公园。在这个初步申请中，要求为四名博士生和四名本科生暑期研究生提供培训支持。MBID培训计划的总体目的是为学员提供1)在微生物研究的最新概念和技术方面培养新科学家的最佳环境；2)更好地了解当前临床传染病面临的挑战；3)在基础研究和临床应用之间“弥合差距”的知识和工具。这项培训赠款的基础是传染病分子基础小组，该小组于1996年首次成立。MBID已经发展成为一个高度互动的小组，有100多名教师、博士后、研究生和来自休斯顿地区的工作人员，他们的主要兴趣是细菌感染的分子发病机制。16名教师组成了这项培训基金的核心，他们有着很高的研究效率和广泛的合作记录。近十年来，共培养博士生、博士后200余人，博士生25人，博士后29人。目前有19名博士预科学员有资格申请NRSA。培训计划将以强大的核心课程、10门发病机理高级课程、密集和互动的研究经验、每月的MBID会议和务静会、研讨会和期刊俱乐部、转化研究和临床传染病的经验为基础。一个为少数族裔服务的大学网络已经建立起来，以帮助招募有前途的本科生参加夏季研究项目和MBID博士项目。这项培训补助金支持的计划活动的一个目标是为博士前微生物学候选人提供临床传染病和转化研究方面的额外知识，从而促进研究转向更迅速地解决重要传染病问题。

DESCRIPTION (provided by applicant): The Molecular Basis of Infectious Disease (MBID) is a research training program consisting of 18 faculty mentors from four Houston educational institutions: the University of Texas Health Science Center at Houston, Baylor College of Medicine, the Texas A&M University Institute for Biosciences and Technology, and the University of Houston, College Park. In this initial application, training support is requested for four Ph.D. students and four undergraduate summer research students. The overall purpose of the MBID training program is to provide the trainees 1) an optimal environment for training new scientists in the latest concepts and techniques in microbiological research; 2) a better understanding of current challenges in clinical infectious diseases; and 3) the knowledge and tools to 'bridge the gap' between basic research and clinical applications. The basis of this training grant is the Molecular Basis of Infectious Disease group, which was first formed in 1996. MBID has developed into highly interactive group of over 100 faculty, postdoctoral fellows, graduate students, and staff from the Houston area whose primary interest is in the molecular pathogenesis of bacterial infections. The 16 faculty members that form the core of this training grant have a record of high research productivity and extensive collaborations. They have mentored over 200 predoctoral and postdoctoral trainees over the past ten years and currently are mentoring 25 Ph.D. students and 29 postdoctoral fellows. Nineteen current predoctoral trainees are eligible for an NRSA. The training program will be based on strong core curricula, 10 advanced courses in pathogenesis, an intensive and interactive research experience, monthly MBID meetings and retreats, seminars and journal clubs, and experience in translational research and clinical infectious diseases. A network of universities serving underrepresented minorities has been established to aid in the recruitment of promising undergraduate students into the summer research program and the MBID Ph.D. program. A goal of the planned activities supported by this training grant is to provide predoctoral microbiology candidates additional knowledge in clinical infectious diseases and translational research, thereby promoting the redirection of research toward the more rapid resolution of important infectious disease problems.