The Maya Angelou Center for Health Equity

在美国，糖尿病是导致死亡和残疾的主要原因。2011年公布的最新估计显示，约有2600万美国人患有糖尿病，约占美国总人口的8.3%。另有7900万美国人患有糖尿病前期，这使得他们患2型糖尿病的风险很高。糖尿病的公共卫生负担在大多数种族和少数民族群体中更加明显。非洲裔美国人和西班牙裔美国人是北卡罗来纳州和美国最大的种族/少数民族群体，2型糖尿病及其相关并发症(包括死亡率)的患病率更高。尽管国家糖尿病预防和控制研究取得了成功，但对于如何在“现实世界”环境中充分实施和采用这些研究和其他研究的结果，以造福于最易患这种常见且代价高昂的疾病的人群，仍明显缺乏了解。最近在联邦一级强调以社区为基础的研究和转化性研究，特别是强调将科学知识转化为对社区有影响的“T4”研究，这可能是解决这些差异的一个关键方面。这一方法需要经过充分培训的科学家和社区内的代表共同努力进行文化上适当的研究。对于拟议的COE，玛雅·安杰卢健康公平中心将开发和实施多管齐下的方法，总体重点是转化基于证据的生活方式战略，以消除糖尿病预防和控制方面的健康差距。MACH COE将实现与将生活方式方法转化为消除糖尿病差异的总体目标相关的以下目标：(1)设计和实施两项以社区为基础的干预研究，重点是糖尿病的预防和控制。

Diabetes mellitus is a leading cause of death and disability in the United States (US). Recent estimates published in 2011 indicate that about 26 million Americans have diabetes, or about 8.3% of the US population. An additional 79 million Americans have pre-diabetes, placing them at high risk for developing type 2 diabetes. The public health burden of diabetes is even more pronounced in most racial and ethnic minority groups. The prevalence of type 2 diabetes and its associated complications, including mortality, are higher for African Americans and Hispanics, the largest racial/ethnic minority groups in North Carolina and the US. Despite the successes seen in national diabetes prevention and control studies, there is a glaring lack of understanding in the ways in which the findings of these and other studies can be adequately implemented and adopted in "real world" settings to provide benefit to the populations that are most vulnerable to this common and costly disease. The recent emphasis on community-based and translational research at the federal level, especially "T4" research, which emphasizes the translation of scientific knowledge to impact the community, can be a key aspect to addressing these disparities. This approach requires a concerted effort between scientists adequately trained in conducting culturally appropriate research and representatives within the community. For the proposed COE, the Maya Angelou Center for Health Equity will develop and implement a multi-pronged approach with the overall focus on translating evidence-based, lifestyle strategies to eliminate health disparities In diabetes prevention and control. The MACHE COE will achieve the following aims pertinent to the overall goal of translating lifestyle approaches for eliminating diabetes disparities: (1) Design and conduct two community-based intervention studies focusing on diabetes prevention and control.