Elizabeth City State University Minority International Research Training Program

伊丽莎白城市州立大学少数族裔国际研究培训计划

• 批准号: 8403393
• 负责人: Ephraim Tobela Gwebu
• 金额: $ 16.29万
• 依托单位: ELIZABETH CITY STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-08 至 2014-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8403393
• 关键词: Affect; Africa; African; Behavioral Research; Bioethics; Biology; Botswana; Caribbean region; Chemistry; Cities; Communities; Data; Diabetes Mellitus; Disease; Educational workshop; Goals; International; Malignant neoplasm of prostate; Medical; Mentors; Minority; Minority Groups; Minority Health and Health Disparities International Research Training; Modality; Morbidity - disease rate; Non-Insulin-Dependent Diabetes Mellitus; Physics; Population; Psychology; Research; Research Personnel; Research Training; Risk Factors; Rural; Series; Site; Social Work; Sociology; South Africa; Students; Training Programs; Travel; Universities; behavioral/social science; combat; drug discovery; experience; health disparity; medically underserved population; meetings; member; minority health; programs; psychosocial; racial and ethnic; symposium; undergraduate student

DESCRIPTION (provided by applicant): The Elizabeth City State University Minority Health and Health Disparities International Research Training (E-MHIRT) Program provides opportunities for undergraduate students from US health disparities populations to conduct research in (i) drug discovery to combat such health disparity diseases as prostate cancer and diabetes and (ii) psycho-socio-behavioral research to identify risk factors for type II diabetes, a disease that disproportionately affects minorities in the USA. Selected honor students are members of US health disparities populations, majoring in biology, chemistry, physics, psychology, sociology and social work. They will spend 10 weeks receiving research training under the tutelage of prominent US and African (foreign) mentors at University of Botswana in Botswana and University of Zululand in South Africa. The E- MHIRT Program is an effort to contribute to the goal of the National Center for Minority Health and Health Disparities of building a diverse, culturally-competent research workforce to promote minority health and eliminate health disparities experienced by racial and ethnic minority, poor, and medically underserved populations in rural and urban communities. E-MHIRT Program components are (1) Pre-Travel Health- Disparities Workshops and Seminar Series to inform trainees about the problems of heath disparities in US and global contexts and related bioethics; (2) Research Training at Foreign Sites in (a) drug discovery with a goal of introducing treatment modalities, derived from Africa's rich traditional medical practice, (b) search for psychosocial risk factors for type 2 diabetes for comparison with data from the USA and Caribbean's in an effort to identify causes of excess diabetes morbidity among health disparities populations; (3) E-MHIRT Symposium at one of the foreign sites where trainees orally present their research findings; (4) Post-travel Activities that include (a) continuation of some of the research in the USA, and (b) Presentations at scientific meetings in the USA. It is hoped that these trainees will be part of a cadre of biomedical/behavioral/ social science researchers that understands health disparities populations and will resolve to contribute to the 7eduction and ultimate elimination of health disparities among US racial and ethnic minority groups.

描述(由申请者提供)：伊丽莎白城市州立大学少数民族健康和健康差异国际研究培训(E-MHIRT)计划为来自美国健康差异人群的本科生提供机会进行以下方面的研究：(I)抗击前列腺癌和糖尿病等健康差异疾病的药物发现；(Ii)心理社会行为研究，以确定II型糖尿病的风险因素，II型糖尿病是一种在美国对少数族裔影响不成比例的疾病。被选中的优等生是美国健康差距人群中的一员，主修生物、化学、物理、心理学、社会学和社会工作。他们将在博茨瓦纳的博茨瓦纳大学和南非的祖鲁兰大学接受为期10周的研究培训，接受美国和非洲(外国)杰出导师的指导。E-MHIRT计划是为了促进国家少数民族健康和健康差距中心的目标，即建立一支多元化的、有文化能力的研究队伍，以促进少数民族健康，消除农村和城市社区中种族和少数民族、贫困人口和医疗服务不足的人群所经历的健康差距。E-MHIRT计划的组成部分是(1)旅行前健康差异讲习班和研讨会系列，向学员介绍美国和全球范围内的健康差异问题和相关的生物伦理；(2)在外国网站的研究培训，目的是介绍来自非洲丰富的传统医疗实践的治疗方式，(B)寻找2型糖尿病的心理社会风险因素，以便与美国和加勒比地区的数据进行比较，以努力确定健康差异人群中糖尿病发病率过高的原因；(3)在一个外国网站举行E-MHIRT研讨会，学员在那里口头介绍他们的研究成果；(4)旅行后活动，包括(A)继续在美国进行一些研究，以及(B)在美国的科学会议上作报告。希望这些受训人员将成为了解健康差距人群的生物医学/行为/社会科学研究队伍的一部分，并决心为美国种族和少数民族群体的教育和最终消除健康差距做出贡献。

项目成果

Semi-synthesis of nitrogen derivatives of oleanolic acid and effect on breast carcinoma MCF-7 cells.

齐墩果酸氮衍生物的半合成及其对乳腺癌MCF-7细胞的影响。

• 发表时间: 2014
• 期刊: Anticancer research
• 影响因子: 2
• 作者: Oyedeji,OpeoluwaO;Shode,FrancisO;Oyedeji,AdebolaO;Songca,SandileP;Gwebu,EphraimT;Hill,GabrielleM;Setzer,WilliamN
• 通讯作者: Setzer,WilliamN

Composition and biological potential of essential oil from Thelechitonia trilobata growing in South Africa.

生长于南非的三裂叶石莲精油的成分和生物潜力。

• 发表时间: 2011
• 期刊: Natural product communications
• 影响因子: 1.8
• 作者: Peebles,Jamie;Gwebu,Ephraim;Oyedeji,Opeoluwa;Nanyonga,Sarah;Kunene,Nokuthula;Jackson,David;Setzer,William;Oyedeji,Adebola
• 通讯作者: Oyedeji,Adebola

Assessment of the analgesic, anti-inflammatory and sedative effects of the dichloromethanol extract of Schinus molle.

毛茛二氯甲醇提取物的镇痛、抗炎和镇静作用的评估。

• 发表时间: 2016
• 期刊: European review for medical and pharmacological sciences
• 影响因子: 3.3
• 作者: Taylor,A;Oyedeji,OO;Aremu,O;Oyemitan,I;Gwebu,ET;Oyedeji,AO;Nkeh-Chungag,BN
• 通讯作者: Nkeh-Chungag,BN

Antihypertensive effects of the hydro-ethanol extract of Senecio serratuloides DC in rats.

锯齿千里光 DC 氢乙醇提取物对大鼠的抗高血压作用。

• DOI: 10.1186/s12906-019-2463-2
• 发表时间: 2019
• 期刊: BMC complementary and alternative medicine
• 作者: Tata,CharlotteMungho;Sewani-Rusike,ConstanceRufaro;Oyedeji,OpeoluwaOyehan;Gwebu,EphraimTobela;Mahlakata,Fikile;Nkeh-Chungag,BenedictaNgwenchi
• 通讯作者: Nkeh-Chungag,BenedictaNgwenchi