Life Events, Depression, and Cognition in Older Age: An Intraindividual Approach

老年生活事件、抑郁和认知：个体方法

• 批准号: 8782527
• 负责人: Robert Steven Stawski
• 金额: $ 6.91万
• 依托单位: OREGON STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-30 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8782527
• 关键词: Life; Events; Depression; Cognition; Older

DESCRIPTION (provided by applicant): Decades of research have linked stressful life events to adverse mental health (e.g., depression) and cognitive outcomes. While research has documented the adverse effects of life events depressive symptoms and cognitive function, less research has explicitly examined such links among older adults, and from an intraindividual (within-person) perspective. Understanding the distribution, occurrence, and timing of life events among older adults, and how these events predict depressive symptoms and cognitive function over time represents a critical challenge for research on stress in aging. Knowing the types, frequency, and timing of life events that older adults experience as they age will provide better insight into their lives and the contextual factors that influence their mental and cognitive healt. Furthermore, longitudinal investigations will provide insight into links between life events, depressive symptoms, and cognitive function within-persons over time, and aging-related vulnerability to the influence of life events. Our project draws on longitudinal data from the Health and Retirement Study (HRS), a nationally-representative study of older adults (age 50+). Specifically, we will use data from the initial HRS cohort (ages 50-60, born 1921-1941) and Assets and Health Dynamics among the Oldest Old (AHEAD) cohort (age 70+, born before 1923), who have provided up to 18-years of biannual longitudinal data through 2010. The design of HRS will allow tracking of life events among older adults longitudinally, as well as modeling associations among life events, depressive symptoms, and cognitive function within-persons over time, to examine concurrent and lagged effects of life events. This study will address three aims: Aim 1 examines the occurrence and timing of life events among older adults; Aim 2 examines the proximal, prospective, and cumulative effects of life events on depressive symptoms and cognitive function; and Aim 3 examines aging-related vulnerability to the effect of life events on depressive symptoms and cognitive function. The significance of this study lies in understanding: 1) the occurrence and timing of life events throughout old age; 2) the proximal, prospective and cumulative effects of life events on depressive symptoms and cognitive function; and 3) aging-related vulnerability to life events. Areas of innovation include: 1) a novel use of large-scale nationally representative survey data to track the experience of life events; 2) the use of longitudinal data to elucidate proximal, prospective, and cumulative effects of life events on depressive symptoms and cognitive function in old age; and 3) the use of analytic techniques for explicitly examining intraindividual associations among life events, depressive symptoms and cognitive function within-person associations over time. PUBLIC HEALTH RELEVANCE: The impact of the proposed research derives from improving our understanding of the life events experienced by older adults and their effects on mental and cognitive health. Identifying the types and timing of life events older adults experience will directly inform intervention and prevention strategies to promote healthy aging. PUBLIC HEALTH RELEVANCE: Using data from the Health and Retirement Study, a nationally representative longitudinal study of the population over 50, this project will examine issues related to experienced life events and their effects on depressive symptoms and cognitive function in a large survey of older adults. This research will help understand the occurrence and timing of life events over the course of aging, and how these life events influence depressive symptoms and cognitive function in the context of aging. It will also contribute to understanding population trends in life event occurrence and their impact on mental and cognitive health, and the identification of high risk individuals/groups.

描述（由申请人提供）：数十年的研究已经将压力生活事件与不良心理健康（如抑郁症）和认知结果联系起来。虽然研究记录了生活事件的负面影响，抑郁症状和认知功能，但很少有研究明确地从个体（个人）的角度检查老年人之间的这种联系。了解老年人生活事件的分布、发生和时间，以及这些事件如何随着时间的推移预测抑郁症状和认知功能，是衰老压力研究的一个关键挑战。了解老年人随着年龄增长所经历的生活事件的类型、频率和时间，将有助于更好地了解他们的生活以及影响他们心理和认知健康的环境因素。此外，纵向调查将深入了解生活事件、抑郁症状和人随着时间的推移的认知功能之间的联系，以及与年龄相关的易受生活事件影响的脆弱性。我们的项目利用了健康与退休研究（HRS）的纵向数据，这是一项具有全国代表性的老年人（50岁以上）研究。具体来说，我们将使用最初HRS队列（年龄50-60岁，1921-1941年出生）和最老（AHEAD）队列（年龄70岁以上，1923年之前出生）的资产和健康动态数据，这些数据提供了截至2010年长达18年的两年一次的纵向数据。HRS的设计将允许对老年人的生活事件进行纵向跟踪，并对生活事件、抑郁症状和人的认知功能之间的关联进行建模，以检查生活事件的并发效应和滞后效应。本研究将有三个目的：目的1检查老年人生活事件的发生和时间；目的2检查生活事件对抑郁症状和认知功能的近端、前瞻性和累积效应；目的3研究与年龄相关的脆弱性对生活事件对抑郁症状和认知功能的影响。本研究的意义在于：1)老年期生活事件的发生与发生时间；2)生活事件对抑郁症状和认知功能的近端效应、预期效应和累积效应；3)与年龄相关的生活事件脆弱性。创新领域包括：

项目成果

Linking widowhood and later-life depressive symptoms: Do childhood socioeconomic circumstances matter?

联系寡妇和后来的抑郁症状：儿童期社会经济环境至关重要吗？

• DOI: 10.1080/13607863.2021.1972930
• 发表时间: 2022-11
• 期刊: Aging & mental health
• 影响因子: 3.4
• 作者: Recksiedler C;Cheval B;Sieber S;Orsholits D;Stawski RS;Cullati S
• 通讯作者: Cullati S