IGF::OT::IGFTitle: Multiplexed Biosensor for Detecting Low Abundance Cancer-rel

IGF::OT::IGFTTitle：用于检测低丰度癌症相关的多重生物传感器

• 批准号: 8761949
• 负责人: KUMAR SUBRAMANIAN
• 金额: $ 99.98万
• 依托单位: PHOENIX BIOSYSTEM, INC.
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-25 至 2015-09-24
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8761949
• 关键词: Biological Assay; Biological Markers; Biosensor; Cancer Detection; Cancer Patient; Communities; Disease; Goals; Individual; Malignant Neoplasms; Patients; Protein Analysis; Research; System; Training; design; flexibility; outcome forecast; programs; prototype; sensor; technology development

Phoenix Biosystem has successfully designed, developed and demonstrated the feasibility of a sensitive, versatile, multiplexed biosensor prototype system for protein analysis during PHASE I. The proposed sensor array will support flexible configuration to assay for several tens of biomarkers in a small footpoint. The goal of the proposed PHASE II research will be to expand the assay menu to include additional cancer biomarkers and develop a fully functional, field deployable prototype to complete the technology development to be done in coordination with the CPTC community to integrate the platform into the techology assessment programs and into the greater scientific community.

Phoenix Biosystem已成功设计、开发并证明了一种灵敏、多功能、多路复用的生物传感器原型系统的可行性，该原型系统用于第一阶段的蛋白质分析。所提出的传感器阵列将支持灵活的配置，以在一个小的足迹中检测几十个生物标志物。拟议的第二阶段研究的目标将是扩大检测菜单，以包括其他癌症生物标志物，并开发一个功能齐全的、可现场部署的原型，以完成与CPTC社区协调完成的技术开发，将平台整合到技术评估计划和更大的科学界。