Home-Based Lithium Level Testing for Bipolar Patients
Home-Based Lithium Level Testing for Bipolar Patients
批准号:
7922943
负责人:
KUMAR SUBRAMANIAN
金额:
$18.36万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-30 至 2011-09-29
关键词:
Biological AssayBiosensorBipolar DisorderBlood BanksBlood specimenBody FluidsBuffersCaringCharacteristicsChronic DiseaseCollaborationsComplexDetectionDevelopmentDisadvantagedDoseDrug MonitoringFamilyFeedbackGlucoseGoalsHealth ProfessionalHome environmentIon-Selective ElectrodesLaboratoriesLaboratory ProceduresLiquid substanceLithiumLithium CarbonateLithonateManicMicrofluidicsModelingMonitorNamesPatientsPerformancePhasePhotometryPlasmaReagentReproducibilityResearchRunningSamplingScheduleSelf ManagementSerumSpecificitySpecimenSpectrum AnalysisSystemTestingTherapeuticTimeUrineValidationWeightabsorptionbasedesignmetermethod developmentperformance testsprototyperesearch studyresponsetoolusability
中文摘要
项目概要
锂,其专有名称包括Eskalith、Lithane、Lithonate、Lithobid和
其他的以碳酸锂的形式给药,用于治疗双相情感障碍。
疾病(BD)、躁狂和躁狂抑郁症。锂的缺点是
治疗范围窄(0.4 - 1.2 mmol/L),需要治疗药物
监测.血清、血浆、尿液或其他体液中锂的浓度
采用火焰发射光度法、原子吸收光谱法、
或使用离子选择性电极进行电化学。血清分析,最有用的
用于锂监测的样品最常通过自动化的
分光光度测定然而,实验室程序复杂且耗时
消耗。随着慢性病自我管理模式的发展,
需要为患者提供监测和管理其护理的工具。一个家
基于锂水平测试将为BD患者及其家属提供工具,
定期监测他们的锂水平,并相应地调整治疗,
由他们的健康专家指导。
Y&ijjf- Of
项目叙述
随着慢性病自我管理模式的发展,越来越需要
为患者提供监测和管理其护理的工具。一种家用锂电池
水平测试将为BD患者及其家属提供监测其
锂水平,并根据他们的指导相应地调整治疗。
健康专业人士。
五^^*7
英文摘要
PROJECT SUMIVIARY
Lithium whose proprietary names include Eskalith, Lithane, Lithonate, Lithobid and
others, is administered as lithium carbonate and used for treatment of the bipolar
disorders (BD), mania, and manic-depressive illness. A disadvantage of lithium is the
narrow therapeutic range (0.4 -1.2 mmol/L), which necessitates therapeutic drug
monitoring. The concentration of lithium in serum, plasma, urine, or other body fluids
have been determined by flame emission photometry, atomic absorption spectroscopy
or electrochemically using ion-selective electrode. Serum analysis, the most useful
specimen for lithium monitoring is most commonly quantified by automated
spectrophotometric assay. However, the laboratory procedures are complex and time
consuming. As chronic disease self-management models evolve, there is an increasing
need to provide patients with the tools to monitor and manage their care. A home-
based lithium level test would provide BD patients and their families with the tools to
monitor their lithium levels on a regular basis and adjust treatment accordingly as
directed by their health professional.
Y&ijjf- Of
PROJECT NARRATIVE
As chronic disease self-management models evolve, there is an increasing need to
provide patients with the tools to monitor and manage their care. A home-based lithium
level test would provide BD patients and their families with the tools to monitor their
lithium levels on a regular basis and adjust treatment accordingly as directed by their
health professional.
V^^*7
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
RAPID POINT OF CARE DIAGNOSTICS FOR HCV
-
批准号:10497110
-
项目类别:
-
资助金额:$30.0万
-
财政年份:2021
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
Low cost, automated smartphone based assay for semen analysis
-
批准号:10028296
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2020
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
Multiplexed Point Of Care Nucleic Acid Assay for STI
-
批准号:9074908
-
项目类别:
-
资助金额:$19.79万
-
财政年份:2016
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
IGF::OT::IGFTitle: Multiplexed Biosensor for Detecting Low Abundance Cancer-rel
-
批准号:8761949
-
项目类别:
-
资助金额:$99.98万
-
财政年份:2013
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
RAPID AND SENSITIVE IDENTIFICATION OF HIV ANTIGEN AT THE POINT OF USE
-
批准号:8603499
-
项目类别:
-
资助金额:$19.62万
-
财政年份:2013
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
Improved methodologies to measure novel alcohol biomarkers in whole blood
-
批准号:8183977
-
项目类别:
-
资助金额:$21.05万
-
财政年份:2012
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
High throughput Point-of-Care assays for diabetes auto-antibody detection
-
批准号:8402736
-
项目类别:
-
资助金额:$28.05万
-
财政年份:2012
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
POINT OF CARE DIAGNOSTICS FOR URINARY TRACT INFECTION
-
批准号:8394577
-
项目类别:
-
资助金额:$29.49万
-
财政年份:2012
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
Multiplexed Biomarkers for staging Alzheimer???s Disease
-
批准号:8371247
-
项目类别:
-
资助金额:$17.08万
-
财政年份:2012
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
High throughput Point-of-Care assays for diabetes auto-antibody detection
-
批准号:8546380
-
项目类别:
-
资助金额:$15.91万
-
财政年份:2012
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
MULTIPLEXED BIOSENSOR FOR DETECTING LOW ABUNDANCE CANCER
-
批准号:8356444
-
项目类别:
-
资助金额:$19.65万
-
财政年份:2011
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
Low-Cost, Onsite Biomarker Test Kits for Alcohol-Associated Disorders (Phoenix)
-
批准号:7947218
-
项目类别:
-
资助金额:$18.25万
-
财政年份:2009
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
BIOMEDICAL (APPLIED/EXPLORATORY)
-
批准号:8039750
-
项目类别:
-
资助金额:$14.56万
-
财政年份:2009
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
Real Time Monitoring of Environmental Exposure To Pesticides
-
批准号:7497426
-
项目类别:
-
资助金额:$29.72万
-
财政年份:2007
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
Real Time Monitoring of Environmental Exposure To Pesticides
-
批准号:7362895
-
项目类别:
-
资助金额:$24.08万
-
财政年份:2007
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
MEMS Based Sternal Skin Conductance Monitoring
-
批准号:7012102
-
项目类别:
-
资助金额:$25.0万
-
财政年份:2005
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
Nanoliter Glucose Assay For Diabetics
-
批准号:6643891
-
项目类别:
-
资助金额:$9.98万
-
财政年份:2003
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
MEMS Based Continuous Alcohol Monitoring Device
-
批准号:6589580
-
项目类别:
-
资助金额:$19.99万
-
财政年份:2002
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
MEMS Based Continuous Alcohol Monitoring Device
-
批准号:7414517
-
项目类别:
-
资助金额:$41.7万
-
财政年份:2002
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
MEMS Based Continuous Alcohol Monitoring Device
-
批准号:7234717
-
项目类别:
-
资助金额:$40.72万
-
财政年份:2002
-
负责人:KUMAR SUBRAMANIAN
-
依托单位:
国内基金
海外基金
NAD+/NADH Biosensor “智能”调控好氧/厌氧耦合供给NADH产氢研究
-
批准号:31970038
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2019
-
负责人:赵洪新
-
依托单位: