BD2K Consortium Activities

来自大数据的生物医学知识因果建模和发现中心（CCMD）的联盟活动组件（CAC）将确保匹兹堡中心参与并融入BD 2K中心联盟的所有活动。与生物医学信息学，计算和系统生物学，哲学，计算机科学，超级计算，统计遗传学，癌症研究，功能磁共振成像和肺部疾病领域的高度合作领导者，我们的CCMD团队将成为数据科学，生物医学等许多学科的广泛接口。作为联盟的一部分，CCMD将为实现以下BD 2K目标做出贡献：1）通过联盟传播CCMD开发的数据和工具; 2）通过与其他联盟网站的合作，扩展数据和软件共享政策和实践; 3）开发新的方法来分析与其他联盟网站集成的大数据，例如与哈佛合作的联盟内项目1中提出的方法; 4）使用基于标准的元数据来描述CCMD工具所使用的数据，例如与斯坦福大学合作的联盟内项目2中提出的那些。我们实现这些目标的方法之一是部署一个技术催化剂，其主要职责是花时间与其他受资助的联盟网站进行学习。该人员的主要职责是编制CCMD技术更新，描述在对其他受资助的BD 2K中心进行季度轮换现场访问期间进行仔细研究后，如何实现CCMD集成和互操作性。作为我们对BD 2K联盟承诺的一部分，CCMD将参与所有联盟会议和联盟的所有小组委员会，如数据共享、出版、监管、评估和指导委员会创建的其他委员会。我们将参与制定并遵守这些委员会制定的所有政策。通过这个CCMD组件，我们将有助于在研究文化的变化，BD 2K已作为其中心目标。

The Consortium Activities Component (CAC) of the Center for Causal Modeling and Discovery (CCMD) of Biomedical Knowledge from Big Data will ensure the Pittsburgh Center's participation and integration into all of the BD2K Center Consortium Activities. With highly collaborative leaders in the fields biomedical informatics, computational and systems biology, philosophy, computer science, supercomputing, statistical genetics, cancer research, fMRI, and lung disease, our CCMD team will serve as a broad interface into many disciplines in data science, biomedicine, and beyond. As part of the Consortium, CCMD will contribute to the achievement of the following BD2K goals: 1) Disseminate data and tools developed by the CCMD through the Consortium; 2) Extend data- and software-sharing policies and practices through collaboration with other Consortium sites; 3) Develop new methods to analyze big data that integrate with other Consortium sites, such as those proposed in Intra-Consortium Project 1 with Harvard; and 4) Use standards-based metadata to describe the data consumed by the tools of CCMD, such as those proposed in Intra-Consortium Project 2 with Stanford. Part of our approach to achieving these goals will be the deployment of a Technical Catalyst whose main responsibility will be to spend time learning with and from the other funded consortium sites. A key responsibility for this individual will be the production of CCMD technical updates describing how CCMD integration and interoperability will be accomplished after careful study during quarterly, rotating site visits of the other funded BD2K Centers. As part of our commitment to the BD2K Consortium, the CCMD will participate in all Consortium meetings and in all of the Consortium subcommittees, such as data sharing, publication, regulatory, evaluation, and others created by the Steering Committee. We will participate in the development of and abide by all policies set by these committees. Through this CCMD component, we will contribute to the change in research culture that BD2K has as its central goal.