Pre-doctoral Training Program in Integrative Vascular Biology

综合血管生物学博士前培训项目

• 批准号: 8451389
• 负责人: NOBUYO MAEDA
• 金额: $ 38.38万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8451389
• 关键词: Biology; Blood Vessels; Training Programs; pre-doctoral

DESCRIPTION (provided by applicant): The pathogenesis of cardiovascular diseases is complex. Accordingly, we propose to train future vascular biologists capable of implementing integrated approaches combining "cellular", "whole animal" and "human" systems through multidisciplinary collaborations that begin during pre-doctoral training. The interdisciplinary pre doctoral training program in Integrative Vascular Biology (IVB) at the University of North Carolina was established in 2002 and has effectively united graduate students who are working in broad disciplines of vascular biology. The success of the IVB Program is clearly demonstrated by the fact that 18 of the 42 trainees received individual fellowships while they were/are in training, and that 22 of 27 past trainees who completed their PhDs are continuing research in academic settings or are residents/students at Medical Schools. The program aims (1) To connect graduate students in broad areas of research related to vascular biology and to cultivate their communication and collaboration skills; (2) To facilitate collaborations through co mentors in different Departments, and thereby integrate a broad knowledge base and skill set relevant to the trainee's thesis research. This renewal application requests funding to continue our IVB Program with support for 12 trainees per year, each up to three years. A new approach in this renewal is to identify outstanding students from under-represented minority backgrounds and guide their vascular biology interest during their first year; one of the trainee positions wil be specifically assigned to support this Fellow. Other trainees will be selected among those who are already in departmental graduate programs at UNC and have chosen thesis projects/mentors in areas related to vascular biology at the end of their first or second year. To encourage a multi-disciplinary approach, we require each trainee to have a collaborating advisor(s) in addition to their conventional primary mentor. The IVB Program is administered by the campus-wide Program for Molecular Biology and Biotechnology. Dr. Nobuyo Maeda, Prof. of Pathology and Laboratory Medicine, is the Director, and Drs. Kathleen Caron, Assoc. Prof. of Cell and Molecular Physiology, and Leslie Parise, Prof. and Chair of Biochemistry and Biophysics, are the Associate Directors. The primary mentors are faculty members at UNC from 13 Departments in four Schools and one College, all of which have a strong commitment to predoctoral training through vascular biology-related research. To form a body of complementing faculty with whom the trainees can choose to collaborate, the primary training faculty are joined by clinical faculty and investigators at UNC who maintain active laboratories staffed primarily with postdoctoral fellows. Support for the IVB community is also provided through the McAlister Heart Institute which offers a seminar series and Core facilities to study vascular biology. With its outstanding history and breadth in vascular biology research, its strong group of investigators, and its strength in animal model studies, the IVB Program at UNC offers an ideal environment for the multidisciplinary training of pre-doctoral students. (End of Abstract)

描述（申请人提供）：心血管疾病的发病机制复杂。因此，我们建议培养未来的血管生物学家，能够通过多学科合作，开始在博士前培训实施综合方法相结合的“细胞”，“整个动物”和“人类”系统。跨学科预 北卡罗来纳州大学的综合血管生物学（IVB）博士培训项目成立于2002年，有效地团结了在血管生物学广泛学科工作的研究生。IVB计划的成功清楚地证明了这一事实，即42名学员中有18人在培训期间获得了个人奖学金，27名完成博士学位的学员中有22人继续在学术环境中进行研究，或者是医学院的住院医生/学生。该项目旨在（1）将血管生物学相关广泛研究领域的研究生联系起来，培养他们的沟通和协作技能;（2）通过合作促进合作 导师在不同的部门，从而整合了广泛的知识基础和技能相关的学员的论文研究。这一更新申请要求提供资金，以继续我们的IVB计划，每年支持12名学员，每名学员最多三年。这次更新的一个新方法是从代表性不足的少数民族背景中识别优秀学生，并在第一年指导他们的血管生物学兴趣;其中一个实习生职位将专门用于支持该研究员。其他学员将从那些已经在斯坦福大学攻读研究生课程，并在第一年或第二年结束时选择了与血管生物学相关的论文项目/导师的人中挑选。为了鼓励多学科的方法，我们要求每个学员除了传统的主要导师外，还要有一个合作顾问。IVB计划由全校分子生物学和生物技术计划管理。病理学和实验室医学教授Nobuyo Maeda博士是主任，细胞和分子生理学副教授Kathleen Caron博士和生物化学和生物物理学教授兼主席Leslie Parise博士是副主任。主要导师是来自四所学校和一所学院的13个部门的教员，所有这些部门都致力于通过血管生物学相关研究进行博士前培训。为了形成一个补充教师的机构，受训者可以选择与之合作，初级培训教师加入了临床教师和研究人员，他们主要由博士后研究员组成的活跃实验室。还通过McAlister心脏研究所为IVB社区提供支持，该研究所提供了一系列研讨会和研究血管生物学的核心设施。凭借其在血管生物学研究方面的杰出历史和广度，其强大的研究人员团队以及其在动物模型研究方面的实力，IVB计划为博士前学生的多学科培训提供了理想的环境。(End摘要）