Administration, Bioinformatics and Biostatistics Core
管理、生物信息学和生物统计学核心
基本信息
- 批准号:8744925
- 负责人:
- 金额:$ 13.61万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2014
- 资助国家:美国
- 起止时间:2014-08-19 至
- 项目状态:未结题
- 来源:
- 关键词:Advisory CommitteesAnnual ReportsBiochemicalBiochemical PathwayBiochemistryBioinformaticsBiometryBiostatistics CoreBudgetsCessation of lifeCollaborationsDataData AnalysesData QualityData SetDevelopmentDiseaseDoctor of MedicineDoctor of PhilosophyEarly DiagnosisEnsureExperimental DesignsHuman ResourcesIceImageryInformaticsInstructionKnowledgeLaboratoriesMalignant NeoplasmsMalignant neoplasm of lungModelingNon-Small-Cell Lung CarcinomaNorth AmericaPathway AnalysisPreparationProtocols documentationQuality ControlReportingResearch PersonnelRoleServicesSystemTranslational ResearchUniversitiesValidationbasecostdata managementimprovedinteroperabilitymeetingsnovel strategiesoperationoutcome forecastprogramsreconstruction
项目摘要
In this Program Project "Systems Biochemistry in Lung Cancer: toward a mechanistic understanding of
NSCLC" we aim to achieve a better understanding of the basic biochemistry of lung cancers as a
prerequisite to mechanism-based reliable early detection of the disease, and to improved approaches to
treatment. The role of the Administrative, Bioinformatics and Biostatistics Core is to provide overall
administration and oversight to the project directors and core leaders (T. W-M. Fan, Ph.D., Project 1; J. Yan,
M.D., Ph.D., Project 2; A. N. Lane, Ph.D., Project 3; R. M, Higashi, Ph.D., Core B, Analytical) on this
Program Project. In addition, Biostatistics and Informatics support (leaders S. N. Rai, Ph.D. and H. N. B
Moseley, Ph.D.) for the Projects will be provided through this Core. To ensure smooth interoperability of the
program, the administrative core will be responsible for maintaining the budgets and cost reporting of the
projects and cores as well as coordinating annual reports, regular meetings among the project personnel and
the internal and external advisory committees. The primary objective of the Bioinformatics / Biostatistics
portion of this core is to provide support for investigators performing translational research and Informatics
for biochemical pathway reconstruction and flux modeling. The core services are matched to the needs of
each project and cover a full range of services from collaboration and routine service; protocol preparation
and review; development of informatics approaches to ensure interoperability; and biochemical network
analysis.
在这个项目中,“肺癌中的系统生物化学:从机理上理解”
我们的目标是更好地了解肺癌的基本生物化学。
以机制为基础的可靠早期发现疾病的先决条件,以及改进的方法
治疗。行政、生物信息学和生物统计核心的作用是全面提供
管理和监督项目主任和核心领导(TW-M)。范军,博士,项目1;严军,
M.D.,Ph.D.,Project 2;A.N.Lane,Ph.D.,Project 3;R.M.,Higashi,Ph.D.,Core B,Analytical)
计划项目。此外,生物统计学和信息学支持(领导S.N.Rai、博士和H.N.B
莫斯利博士)这些项目将通过这一核心提供。为确保
方案,行政核心将负责维持预算和成本报告
项目和核心以及协调年度报告、项目人员定期会议和
内部和外部咨询委员会。生物信息学/生物统计学的主要目标
这一核心的一部分是为执行翻译研究和信息学的调查人员提供支持
用于生化途径重建和通量建模。核心服务与以下需求相匹配
每个项目并涵盖从协作到日常服务的全方位服务;协议准备
和审查;发展信息学方法以确保互操作性;以及生化网络
分析。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Teresa Whei-Mei Fan其他文献
Teresa Whei-Mei Fan的其他文献
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{{ truncateString('Teresa Whei-Mei Fan', 18)}}的其他基金
Mitochondrial Metabolic Reprogramming and DNA Damage in Arsenic Carcinogenesis
砷致癌过程中的线粒体代谢重编程和 DNA 损伤
- 批准号:
9090111 - 财政年份:2015
- 资助金额:
$ 13.61万 - 项目类别:
Mitochondrial Metabolic Reprogramming and DNA Damage in Arsenic Carcinogenesis
砷致癌过程中的线粒体代谢重编程和 DNA 损伤
- 批准号:
8927921 - 财政年份:2015
- 资助金额:
$ 13.61万 - 项目类别:
Determining Tumor Metabolism and Biochemical Mechanism of beta-glucan Action in
确定肿瘤代谢和 β-葡聚糖作用的生化机制
- 批准号:
8744923 - 财政年份:2014
- 资助金额:
$ 13.61万 - 项目类别:
Integrated Chemoselective and Informatic Platform for Large-Scale Metabolomics
用于大规模代谢组学的集成化学选择性和信息平台
- 批准号:
8914844 - 财政年份:2014
- 资助金额:
$ 13.61万 - 项目类别:
Integrated Chemoselective and Informatic Platform for Large-Scale Metabolomics
用于大规模代谢组学的集成化学选择性和信息平台
- 批准号:
8916721 - 财政年份:2014
- 资助金额:
$ 13.61万 - 项目类别:
Systems Biochemistry in Lung Cancer: Toward a Mechanistic Understanding of NSCLC
肺癌的系统生物化学:了解非小细胞肺癌的机制
- 批准号:
9025455 - 财政年份:2014
- 资助金额:
$ 13.61万 - 项目类别:
Microenvironmental Nutrient Availability and Immunomodulation in Lung Cancer Cel
肺癌细胞的微环境营养素利用率和免疫调节
- 批准号:
8744921 - 财政年份:2014
- 资助金额:
$ 13.61万 - 项目类别:
Determining Molecular Mechanisms of NSCLC and Response to beta-glucan
确定 NSCLC 的分子机制和对 β-葡聚糖的反应
- 批准号:
8744924 - 财政年份:2014
- 资助金额:
$ 13.61万 - 项目类别:
Stable Isotope Resolved Metabolomics Analytical Shared Core
稳定同位素解析代谢组学分析共享核心
- 批准号:
8744926 - 财政年份:2014
- 资助金额:
$ 13.61万 - 项目类别:
Integrated Chemoselective and Informatic Platform for Large-Scale Metabolomics
用于大规模代谢组学的集成化学选择性和信息平台
- 批准号:
8687656 - 财政年份:2014
- 资助金额:
$ 13.61万 - 项目类别:
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